STRINGSTRING
IGF2 IGF2 TBX21 TBX21 MZB1 MZB1 CUNH20orf196 CUNH20orf196 FBXO38 FBXO38 NDFIP1 NDFIP1 GFER GFER TFRC TFRC MASP1 MASP1 BCL6 BCL6 APPL1 APPL1 NLRX1 NLRX1 MSH2 MSH2 PANX1 PANX1 A306_00015283 A306_00015283 A306_00011800 A306_00011800 ZPBP2 ZPBP2 BLK BLK A306_00010686 A306_00010686 HSPD1 HSPD1 A306_00010010 A306_00010010 CUEDC2 CUEDC2 ADORA2B ADORA2B MLH1 MLH1 IL10 IL10 MAPKAPK2 MAPKAPK2 A306_00007333 A306_00007333 CD46 CD46 CR1 CR1 A306_00009652 A306_00009652 SMAD7 SMAD7 IL12A IL12A DHX36 DHX36 C1QBP C1QBP NCF1 NCF1 RABGEF1 RABGEF1 CD40 CD40 A306_00006194 A306_00006194 TNFRSF1B TNFRSF1B TNFRSF4 TNFRSF4 MASP2 MASP2 CARD9 CARD9 RC3H2 RC3H2 IL20RB IL20RB A306_00008815 A306_00008815 A306_00008814 A306_00008814 HLX HLX DUSP10 DUSP10 SUSD4 SUSD4 TGFB2 TGFB2 DDX58 DDX58 SYK SYK A306_00006774 A306_00006774 A306_00006842 A306_00006842 SEMA7A SEMA7A TP53BP1 TP53BP1 ATAD5 ATAD5 GPI GPI XBP1 XBP1 FER FER CD74 CD74 IL12B IL12B SOCS5 SOCS5 SH2D1A SH2D1A DENND1B DENND1B PTPRC PTPRC RC3H1 RC3H1 SIRT1 SIRT1 A306_00005221 A306_00005221 A306_00005222 A306_00005222 EXOSC3 EXOSC3 FAM35A FAM35A A306_00007934 A306_00007934 A306_00007935 A306_00007935 SNX4 SNX4 RIF1 RIF1 IL21 IL21 ANKRD17 ANKRD17 GATA3 GATA3 FGL2 FGL2 CRTAM CRTAM CADM1 CADM1 KMT5B KMT5B CD59 CD59 FADD FADD A306_00004086 A306_00004086 A306_00004087 A306_00004087 DNAJB9 DNAJB9 CUNH12orf4 CUNH12orf4 APPL2 APPL2 SH2D1B SH2D1B CD86 CD86 PTPN6 PTPN6 CD96 CD96 MAVS MAVS KIT KIT TLR3 TLR3 WHSC1 WHSC1 SPON2 SPON2 ZBTB1 ZBTB1 TGFB3 TGFB3 RASGRP1 RASGRP1 IL6 IL6 AHR AHR TGFBR2 TGFBR2 TRIL TRIL LAMP1 LAMP1 IL18R1 IL18R1 IL18RAP IL18RAP LACC1 LACC1 NFKBIZ NFKBIZ ATG5 ATG5 PRAM1 PRAM1 UBE2J1 UBE2J1 MYB MYB MB21D1 MB21D1 MAP3K7 MAP3K7 A306_00001142 A306_00001142 A306_00001143 A306_00001143 COLEC11 COLEC11 RSAD2 RSAD2 LYN LYN COLEC10 COLEC10 THOC1 THOC1 FAM49B FAM49B RIPK2 RIPK2 VAMP8 VAMP8 CX3CR1 CX3CR1 NOD1 NOD1 IL1B IL1B SERPING1 SERPING1 HMCES HMCES A306_00000498 A306_00000498 A306_00015133 A306_00015133 A306_00013655 A306_00013655 GRN GRN A306_00013682 A306_00013682 ARID5A ARID5A MALT1 MALT1 DHX58 DHX58 SUPT6H SUPT6H A306_00014370 A306_00014370 TRAF6 TRAF6 A306_00000392 A306_00000392 A306_00000459 A306_00000459 A306_00000373 A306_00000373 APOA1 APOA1 IL7R IL7R A306_00012732 A306_00012732 ZC3H12A ZC3H12A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IGF2Insulin-like growth factor 2. (146 aa)
TBX21T-box 21. (168 aa)
MZB1Marginal zone B and B1 cell-specific protein. (193 aa)
CUNH20orf196Uncharacterized protein. (227 aa)
FBXO38F-box protein 38. (1181 aa)
NDFIP1Nedd4 family interacting protein 1. (203 aa)
GFERSulfhydryl oxidase. (93 aa)
TFRCTransferrin receptor, transcript variant X1. (777 aa)
MASP1Mannan-binding lectin serine protease 1 isoform X1; Belongs to the peptidase S1 family. (802 aa)
BCL6B-cell CLL/lymphoma 6. (709 aa)
APPL1Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1. (704 aa)
NLRX1NLR family member X1. (602 aa)
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1021 aa)
PANX1Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family. (370 aa)
A306_00015283Protein C12orf4 homolog. (168 aa)
A306_00011800Angiopoietin-related protein 7. (444 aa)
ZPBP2Zona pellucida binding protein 2. (315 aa)
BLKTyrosine-protein kinase. (526 aa)
A306_00010686Serine protease inhibitor Kazal-type 5-like. (255 aa)
HSPD1Heat shock 60kDa protein 1 (Chaperonin); Belongs to the chaperonin (HSP60) family. (567 aa)
A306_00010010Killer cell lectin-like receptor subfamily G member 1. (189 aa)
CUEDC2CUE domain containing 2. (284 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (352 aa)
MLH1MutL homolog 1. (688 aa)
IL10Interleukin 10. (176 aa)
MAPKAPK2Mitogen-activated protein kinase-activated protein kinase 2. (309 aa)
A306_00007333Uncharacterized protein C1orf106. (266 aa)
CD46CD46 molecule, complement regulatory protein. (444 aa)
CR1Complement component (3b/4b) receptor 1 (Knops blood group). (3200 aa)
A306_00009652Receptor-interacting serine/threonine-protein kinase 2. (541 aa)
SMAD7Mothers against decapentaplegic homolog. (290 aa)
IL12AInterleukin-12 subunit alpha; Belongs to the IL-6 superfamily. (186 aa)
DHX36DEAH (Asp-Glu-Ala-His) box polypeptide 36. (968 aa)
C1QBPComplement component 1, q subcomponent binding protein. (202 aa)
NCF1Neutrophil cytosolic factor 1. (409 aa)
RABGEF1RAB guanine nucleotide exchange factor (GEF) 1, transcript variant X3. (538 aa)
CD40CD40 molecule, TNF receptor superfamily member 5. (276 aa)
A306_00006194Phospholipase A(2). (138 aa)
TNFRSF1BTumor necrosis factor receptor superfamily, member 1B. (475 aa)
TNFRSF4Tumor necrosis factor receptor superfamily, member 4. (337 aa)
MASP2Mannan-binding lectin serine peptidase 2, transcript variant X2. (290 aa)
CARD9Caspase recruitment domain family, member 9. (541 aa)
RC3H2Ring finger and CCCH-type domains 2, transcript variant X3. (1191 aa)
IL20RBInterleukin 20 receptor beta. (266 aa)
A306_00008815Deoxyribonuclease; Belongs to the DNase I family. (278 aa)
A306_00008814Deoxyribonuclease; Belongs to the DNase I family. (285 aa)
HLXH2.0-like homeobox. (301 aa)
DUSP10Dual specificity phosphatase 10. (479 aa)
SUSD4Sushi domain containing 4. (556 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
DDX58DEAD (Asp-Glu-Ala-Asp) box polypeptide 58. (730 aa)
SYKTyrosine-protein kinase. (617 aa)
A306_00006774Zona pellucida sperm-binding protein 3. (434 aa)
A306_00006842Zona pellucida sperm-binding protein 3. (453 aa)
SEMA7ASemaphorin 7A, GPI membrane anchor (John Milton Hagen blood group), transcript variant X1; Belongs to the semaphorin family. (633 aa)
TP53BP1Tumor protein p53 binding protein 1. (1821 aa)
ATAD5ATPase family, AAA domain containing 5. (1851 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (544 aa)
XBP1X-box binding protein 1. (197 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
CD74CD74 molecule, major histocompatibility complex, class II invariant chain, transcript variant X1. (278 aa)
IL12BInterleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (315 aa)
SOCS5Suppressor of cytokine signaling 5. (373 aa)
SH2D1ASH2 domain containing 1A. (127 aa)
DENND1BDENN/MADD domain containing 1B. (847 aa)
PTPRCProtein tyrosine phosphatase, receptor type, C, transcript variant X1. (1247 aa)
RC3H1Ring finger and CCCH-type domains 1, transcript variant X1. (1130 aa)
SIRT1Sirtuin 1, transcript variant X1. (606 aa)
A306_00005221Nucleolar RNA helicase 2-like. (558 aa)
A306_00005222Nucleolar RNA helicase 2-like. (328 aa)
EXOSC3Exosome component 3. (231 aa)
FAM35AFamily with sequence similarity 35, member A. (486 aa)
A306_00007934Annexin. (343 aa)
A306_00007935Annexin. (177 aa)
SNX4Sorting nexin 4. (402 aa)
RIF1Replication timing regulatory factor 1. (2314 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (145 aa)
ANKRD17Ankyrin repeat domain 17. (2543 aa)
GATA3GATA binding protein 3, transcript variant X1. (444 aa)
FGL2Fibrinogen-like 2. (442 aa)
CRTAMCytotoxic and regulatory T cell molecule. (531 aa)
CADM1Cell adhesion molecule 1. (617 aa)
KMT5BSET domain-containing protein. (857 aa)
CD59CD59 molecule, complement regulatory protein. (116 aa)
FADDFas (TNFRSF6)-associated via death domain. (195 aa)
A306_00004086Aryl hydrocarbon receptor-like, transcript variant X1. (894 aa)
A306_00004087Aryl hydrocarbon receptor. (890 aa)
DNAJB9DnaJ (Hsp40) homolog, subfamily B, member 9, transcript variant X1. (215 aa)
CUNH12orf4Uncharacterized protein. (387 aa)
APPL2Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2. (495 aa)
SH2D1BSH2 domain containing 1B. (134 aa)
CD86CD86 molecule. (283 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (608 aa)
CD96CD96 molecule. (596 aa)
MAVSMitochondrial antiviral signaling protein. (632 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (963 aa)
TLR3Toll-like receptor 3; Belongs to the Toll-like receptor family. (895 aa)
WHSC1Wolf-Hirschhorn syndrome candidate 1. (1394 aa)
SPON2Spondin 2, extracellular matrix protein, transcript variant X1. (387 aa)
ZBTB1Zinc finger and BTB domain containing 1, transcript variant X1. (711 aa)
TGFB3Transforming growth factor, beta 3. (456 aa)
RASGRP1RAS guanyl releasing protein 1 (Calcium and DAG-regulated). (840 aa)
IL6Interleukin 6. (150 aa)
AHRAryl hydrocarbon receptor. (841 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (633 aa)
TRILTLR4 interactor with leucine-rich repeats. (522 aa)
LAMP1Lysosomal-associated membrane protein 1. (419 aa)
IL18R1Interleukin 18 receptor 1. (565 aa)
IL18RAPInterleukin 18 receptor accessory protein. (669 aa)
LACC1Laccase (Multicopper oxidoreductase) domain containing 1. (437 aa)
NFKBIZNuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta. (660 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
PRAM1PML-RARA regulated adaptor molecule 1. (415 aa)
UBE2J1Ubiquitin-conjugating enzyme E2, J1. (315 aa)
MYBV-myb avian myeloblastosis viral oncogene homolog. (750 aa)
MB21D1Mab-21 domain containing 1. (313 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7, transcript variant X1. (194 aa)
A306_00001142Interleukin-17A. (169 aa)
A306_00001143Interleukin-17F. (169 aa)
COLEC11Collectin sub-family member 11, transcript variant X1. (277 aa)
RSAD2Radical S-adenosyl methionine domain containing 2. (329 aa)
LYNTyrosine-protein kinase. (513 aa)
COLEC10Collectin sub-family member 10 (C-type lectin). (277 aa)
THOC1THO complex 1. (649 aa)
FAM49BFamily with sequence similarity 49, member B, transcript variant X1. (324 aa)
RIPK2Receptor-interacting serine-threonine kinase 2. (547 aa)
VAMP8Vesicle-associated membrane protein 8. (136 aa)
CX3CR1Chemokine (C-X3-C motif) receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa)
NOD1Nucleotide-binding oligomerization domain-containing protein 1. (951 aa)
IL1BInterleukin-1; Belongs to the IL-1 family. (269 aa)
SERPING1Serpin peptidase inhibitor, clade G (C1 inhibitor), member 1; Belongs to the serpin family. (342 aa)
HMCESAbasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...] (265 aa)
A306_00000498Ig-like domain-containing protein. (107 aa)
A306_00015133Complement receptor type 2. (275 aa)
A306_00013655Mucosa-associated lymphoid tissue lymphoma translocation protein 1-like. (514 aa)
GRNGranulin. (265 aa)
A306_00013682Signaling lymphocytic activation molecule. (368 aa)
ARID5AAT rich interactive domain 5A (MRF1-like). (169 aa)
MALT1MALT1 paracaspase. (474 aa)
DHX58DEXH (Asp-Glu-X-His) box polypeptide 58. (674 aa)
SUPT6HTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1722 aa)
A306_00014370Ficolin-2. (318 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa)
A306_00000392Uncharacterized protein. (261 aa)
A306_00000459SCY domain-containing protein. (126 aa)
A306_00000373CASPASE_P20 domain-containing protein. (209 aa)
APOA1Apolipoprotein A-I. (264 aa)
IL7RInterleukin 7 receptor. (462 aa)
A306_00012732Putative LOC102087174. (403 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (642 aa)
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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