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TDO2 TDO2 PPCS PPCS DLST DLST A306_00002125 A306_00002125 PDHX PDHX MPC2 MPC2 PDHA1 PDHA1 AASS AASS HMGCS2 HMGCS2 ACAT1 ACAT1 PDHB PDHB MVK MVK A306_00009351 A306_00009351 ACSS2 ACSS2 MLYCD MLYCD DIP2A DIP2A ACSS1 ACSS1 HMGCS1 HMGCS1 DLAT DLAT AADAT AADAT ACLY ACLY PIPOX PIPOX MVD MVD NUDT8 NUDT8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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TDO2Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (406 aa)
PPCSPhosphopantothenoylcysteine synthetase, transcript variant X1. (138 aa)
DLSTDihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex). (446 aa)
A306_00002125Acetyl-coenzyme A synthetase. (686 aa)
PDHXDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (503 aa)
MPC2Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (79 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (422 aa)
AASSAminoadipate-semialdehyde synthase, transcript variant X1. (950 aa)
HMGCS23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (403 aa)
ACAT1Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (422 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (331 aa)
MVKMevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (397 aa)
A306_00009351Peroxisomal coenzyme A diphosphatase NUDT7. (259 aa)
ACSS2Acyl-CoA synthetase short-chain family member 2. (464 aa)
MLYCDMalonyl-CoA decarboxylase. (474 aa)
DIP2ADisco-interacting protein 2 homolog A. (1207 aa)
ACSS1Acetyl-coenzyme A synthetase. (599 aa)
HMGCS13-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (522 aa)
DLATAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (548 aa)
AADATAminoadipate aminotransferase. (425 aa)
ACLYATP citrate lyase. (1068 aa)
PIPOXPipecolic acid oxidase. (392 aa)
MVDDiphosphomevalonate decarboxylase. (356 aa)
NUDT8Nudix (Nucleoside diphosphate linked moiety X)-type motif 8. (140 aa)
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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