116 items (Columba livia) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3. (254 aa)
	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta. (200 aa)
	NKIRAS2	NFKB inhibitor interacting Ras-like 2, transcript variant X1. (191 aa)
	CUNH15orf62	Uncharacterized protein. (176 aa)
	RAB9A	RAB9A, member RAS oncogene family. (201 aa)
	CDC42EP1	CDC42 effector protein (Rho GTPase binding) 1, transcript variant X1. (417 aa)
	CTNNAL1	Catenin (Cadherin-associated protein), alpha-like 1. (722 aa)
	RAB12	RAB12, member RAS oncogene family. (186 aa)
	ROCK1	Rho-associated, coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1408 aa)
	RAB4A	RAB4A, member RAS oncogene family. (208 aa)
	RHOU	Ras homolog family member U. (308 aa)
	ROCK2	Rho-associated, coiled-coil containing protein kinase 2, transcript variant X1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1356 aa)
	WASF1	WAS protein family, member 1. (507 aa)
	RB1	Retinoblastoma 1. (901 aa)
	NKIRAS1	NFKB inhibitor interacting Ras-like 1. (191 aa)
	RAPGEF5	Rap guanine nucleotide exchange factor (GEF) 5. (425 aa)
	RASGRP1	RAS guanyl releasing protein 1 (Calcium and DAG-regulated). (840 aa)
	RHOV	Ras homolog family member V. (256 aa)
	ARHGAP5	Rho GTPase activating protein 5. (1505 aa)
	A306_00002009	Synaptojanin-2-binding protein. (209 aa)
	RHOH	Ras homolog family member H. (191 aa)
	CYFIP1	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
	KRAS	Uncharacterized protein. (197 aa)
	RAP1B	RAP1B, member of RAS oncogene family. (184 aa)
	SGSM3	Small G protein signaling modulator 3. (753 aa)
	RAPGEF4	Rap guanine nucleotide exchange factor (GEF) 4, transcript variant X1. (1026 aa)
	RRAS2	Uncharacterized protein. (275 aa)
	HRAS	Uncharacterized protein. (189 aa)
	RAB33B	RAB33B, member RAS oncogene family. (156 aa)
	RASGEF1B	RasGEF domain family, member 1B. (458 aa)
	CCNA2	Cyclin A2; Belongs to the cyclin family. (288 aa)
	RALB	V-ral simian leukemia viral oncogene homolog B, transcript variant X1. (206 aa)
	MRAS	Muscle RAS oncogene homolog, transcript variant X1. (208 aa)
	RASGEF1A	RasGEF domain family, member 1A. (483 aa)
	SHTN1	Shootin 1. (597 aa)
	GPSM2	G-protein signaling modulator 2. (663 aa)
	RASGRF1	Ras protein-specific guanine nucleotide-releasing factor 1. (1257 aa)
	USP8	Ubiquitin specific peptidase 8, transcript variant X3; Belongs to the peptidase C19 family. (1121 aa)
	USP50	Ubiquitin carboxyl-terminal hydrolase. (420 aa)
	RAB39A	RAB39A, member RAS oncogene family. (198 aa)
	RALGPS2	Ral GEF with PH domain and SH3 binding motif 2. (584 aa)
	JUN	Jun proto-oncogene; Belongs to the bZIP family. (338 aa)
	AGTR1	Angiotensin II receptor, type 1; Belongs to the G-protein coupled receptor 1 family. (359 aa)
	A306_00007489	Rho-related GTP-binding protein RhoG, transcript variant X1. (191 aa)
	RAPGEF6	Rap guanine nucleotide exchange factor (GEF) 6. (1659 aa)
	RASGEF1C	RasGEF domain family, member 1C. (449 aa)
	MAPKAPK5	Mitogen-activated protein kinase-activated protein kinase 5, transcript variant X1. (407 aa)
	BRAP	BRCA1 associated protein. (561 aa)
	A306_00009325	KIAA0355 ortholog. (1031 aa)
	ADGRG1	Adhesion G protein-coupled receptor G1; Belongs to the G-protein coupled receptor 2 family. (748 aa)
	CDC42EP4	CDC42 effector protein (Rho GTPase binding) 4. (289 aa)
	GNA13	Guanine nucleotide binding protein (G protein), alpha 13. (371 aa)
	RAP2C	RAP2C, member of RAS oncogene family. (185 aa)
	RAB9B	RAB9B, member RAS oncogene family. (201 aa)
	ARHGDIG	Rho GDP dissociation inhibitor (GDI) gamma. (150 aa)
	RALGPS1	Ral GEF with PH domain and SH3 binding motif 1. (562 aa)
	RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1. (1032 aa)
	PDPN	Podoplanin, transcript variant X1. (147 aa)
	RABGEF1	RAB guanine nucleotide exchange factor (GEF) 1, transcript variant X3. (538 aa)
	RAB30	RAB30, member RAS oncogene family. (203 aa)
	GNA12	Guanine nucleotide binding protein (G protein) alpha 12. (302 aa)
	RIT2	Ras-like without CAAX 2. (217 aa)
	NRAS	Neuroblastoma RAS viral (V-ras) oncogene homolog. (123 aa)
	CSDE1	Cold shock domain containing E1, RNA-binding. (796 aa)
	RAP1A	RAP1A, member of RAS oncogene family. (128 aa)
	RAB21	RAB21, member RAS oncogene family. (199 aa)
	TMEM19	Transmembrane protein 19. (443 aa)
	RAB35	RAB35, member RAS oncogene family. (204 aa)
	KSR2	Kinase suppressor of ras 2. (903 aa)
	KSR1	Kinase suppressor of ras 1. (534 aa)
	TAX1BP3	PDZ domain-containing protein. (121 aa)
	RASGRP3	RAS guanyl releasing protein 3 (Calcium and DAG-regulated), transcript variant X1. (693 aa)
	PLCE1	Phospholipase C, epsilon 1. (1367 aa)
	EPS8	Epidermal growth factor receptor pathway substrate 8. (828 aa)
	RERG	RAS-like, estrogen-regulated, growth inhibitor, transcript variant X1. (199 aa)
	PLEKHG7	Pleckstrin homology domain containing, family G (With RhoGef domain) member 7. (500 aa)
	A306_00013498	Protein phosphatase 1 regulatory subunit 21. (551 aa)
	A306_00013499	Protein phosphatase 1 regulatory subunit 21. (185 aa)
	RASGRF2	Ras protein-specific guanine nucleotide-releasing factor 2. (1238 aa)
	BCL6	B-cell CLL/lymphoma 6. (709 aa)
	RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2, transcript variant X1. (1618 aa)
	RALA	V-ral simian leukemia viral oncogene homolog A (Ras related), transcript variant X1. (206 aa)
	SOS1	Uncharacterized protein. (1323 aa)
	NISCH	Nischarin. (1401 aa)
	RASSF1	Ras association (RalGDS/AF-6) domain family member 1. (264 aa)
	SOS2	Uncharacterized protein. (1183 aa)
	NGFR	Nerve growth factor receptor. (276 aa)
	KPNB1	Karyopherin (Importin) beta 1, transcript variant X2. (842 aa)
	DOK2	Docking protein 2, 56kDa. (474 aa)
	CDC42	Cell division cycle 42, transcript variant X2. (191 aa)
	USP28	Ubiquitin specific peptidase 28; Belongs to the peptidase C19 family. (562 aa)
	EPS8L2	EPS8-like 2. (736 aa)
	RFXANK	Regulatory factor X-associated ankyrin-containing protein. (282 aa)
	RHOG	Ras homolog family member G. (236 aa)
	MYO9B	Myosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1833 aa)
	RACGAP1	Uncharacterized protein. (658 aa)
	NTN1	Netrin 1. (572 aa)
	ITGA3	Integrin, alpha 3 (Antigen CD49C, alpha 3 subunit of VLA-3 receptor). (799 aa)
	A306_00000231	Phosphatase and actin regulator. (476 aa)
	ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha. (200 aa)
	FAM65A	Family with sequence similarity 65, member A. (1059 aa)
	FARP2	FERM, RhoGEF and pleckstrin domain protein 2. (526 aa)
	RAB33A	RAB33A, member RAS oncogene family. (212 aa)
	RIT1	Ras-like without CAAX 1, transcript variant X1. (206 aa)
	SETDB1	SET domain, bifurcated 1. (747 aa)
	RAPGEFL1	Rap guanine nucleotide exchange factor (GEF)-like 1. (500 aa)
	WASF2	WAS protein family, member 2. (252 aa)
	DBNL	Drebrin-like. (537 aa)
	DOK1	Docking protein 1, 62kDa (Downstream of tyrosine kinase 1). (181 aa)
	CNKSR1	Connector enhancer of kinase suppressor of Ras 1. (618 aa)
	RAPGEF3	Rap guanine nucleotide exchange factor (GEF) 3. (710 aa)
	ARHGAP35	Rho GTPase activating protein 35. (630 aa)
	DOK3	Docking protein 3. (423 aa)
	A306_00015010	Rac GTPase-activating protein 1. (586 aa)
	RAB4B	RAB4B, member RAS oncogene family. (137 aa)
	A306_00015291	Rap guanine nucleotide exchange factor 3. (86 aa)

Your Current Organism:

Columba livia

NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A306_00007489	A306_00009325	A0A2I0MAY8	A0A2I0M7W9	Rho-related GTP-binding protein RhoG, transcript variant X1.	KIAA0355 ortholog.	0.565
A306_00007489	A306_00015010	A0A2I0MAY8	A0A2I0LGY6	Rho-related GTP-binding protein RhoG, transcript variant X1.	Rac GTPase-activating protein 1.	0.451
A306_00007489	ARHGAP35	A0A2I0MAY8	A0A2I0LIN9	Rho-related GTP-binding protein RhoG, transcript variant X1.	Rho GTPase activating protein 35.	0.452
A306_00007489	ARHGAP5	A0A2I0MAY8	A0A2I0MNN8	Rho-related GTP-binding protein RhoG, transcript variant X1.	Rho GTPase activating protein 5.	0.446
A306_00007489	ARHGDIA	A0A2I0MAY8	A0A2I0LMR7	Rho-related GTP-binding protein RhoG, transcript variant X1.	Rho GDP dissociation inhibitor (GDI) alpha.	0.671
A306_00007489	ARHGDIB	A0A2I0MAY8	R7VVM7	Rho-related GTP-binding protein RhoG, transcript variant X1.	Rho GDP dissociation inhibitor (GDI) beta.	0.671
A306_00007489	ARHGDIG	A0A2I0MAY8	A0A2I0M4C7	Rho-related GTP-binding protein RhoG, transcript variant X1.	Rho GDP dissociation inhibitor (GDI) gamma.	0.671
A306_00007489	CDC42	A0A2I0MAY8	A0A2I0LQU0	Rho-related GTP-binding protein RhoG, transcript variant X1.	Cell division cycle 42, transcript variant X2.	0.565
A306_00007489	CYFIP1	A0A2I0MAY8	A0A2I0MLK0	Rho-related GTP-binding protein RhoG, transcript variant X1.	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.	0.655
A306_00007489	MYO9B	A0A2I0MAY8	A0A2I0LPD2	Rho-related GTP-binding protein RhoG, transcript variant X1.	Myosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.779
A306_00007489	RACGAP1	A0A2I0MAY8	A0A2I0LPA5	Rho-related GTP-binding protein RhoG, transcript variant X1.	Uncharacterized protein.	0.451
A306_00007489	RAPGEF1	A0A2I0MAY8	A0A2I0M3R2	Rho-related GTP-binding protein RhoG, transcript variant X1.	Rap guanine nucleotide exchange factor (GEF) 1.	0.471
A306_00007489	RHOG	A0A2I0MAY8	A0A2I0LPI6	Rho-related GTP-binding protein RhoG, transcript variant X1.	Ras homolog family member G.	0.901
A306_00007489	ROCK1	A0A2I0MAY8	A0A2I0MW50	Rho-related GTP-binding protein RhoG, transcript variant X1.	Rho-associated, coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.447
A306_00007489	ROCK2	A0A2I0MAY8	A0A2I0MUM6	Rho-related GTP-binding protein RhoG, transcript variant X1.	Rho-associated, coiled-coil containing protein kinase 2, transcript variant X1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.425
A306_00007489	SOS1	A0A2I0MAY8	A0A2I0LT24	Rho-related GTP-binding protein RhoG, transcript variant X1.	Uncharacterized protein.	0.418
A306_00007489	SOS2	A0A2I0MAY8	A0A2I0LSI0	Rho-related GTP-binding protein RhoG, transcript variant X1.	Uncharacterized protein.	0.418
A306_00009325	A306_00007489	A0A2I0M7W9	A0A2I0MAY8	KIAA0355 ortholog.	Rho-related GTP-binding protein RhoG, transcript variant X1.	0.565
A306_00009325	CDC42	A0A2I0M7W9	A0A2I0LQU0	KIAA0355 ortholog.	Cell division cycle 42, transcript variant X2.	0.512
A306_00009325	RHOG	A0A2I0M7W9	A0A2I0LPI6	KIAA0355 ortholog.	Ras homolog family member G.	0.565