STRINGSTRING
RUSC2 RUSC2 HMGCS1 HMGCS1 RDH10 RDH10 FDFT1 FDFT1 RBP1 RBP1 LSS LSS HMGCR HMGCR ALDH1A2 ALDH1A2 MVK MVK RPE65 RPE65 ALDH1A3 ALDH1A3 HMGCS2 HMGCS2 COQ2 COQ2 A306_00002460 A306_00002460 PDSS1 PDSS1 ISPD ISPD PDSS2 PDSS2 ALDH8A1 ALDH8A1 GGPS1 GGPS1 NUS1 NUS1 DHDDS DHDDS MVD MVD FDPS FDPS RUSC1 RUSC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RUSC2RUN and SH3 domain containing 2, transcript variant X1. (1614 aa)
HMGCS13-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (522 aa)
RDH10Retinol dehydrogenase 10 (All-trans); Belongs to the short-chain dehydrogenases/reductases (SDR) family. (245 aa)
FDFT1Farnesyl-diphosphate farnesyltransferase 1. (390 aa)
RBP1Retinol binding protein 1, cellular; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa)
LSSTerpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (634 aa)
HMGCR3-hydroxy-3-methylglutaryl coenzyme A reductase. (882 aa)
ALDH1A2Aldehyde dehydrogenase 1 family, member A2; Belongs to the aldehyde dehydrogenase family. (549 aa)
MVKMevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (397 aa)
RPE65Retinal pigment epithelium-specific protein 65kDa. (530 aa)
ALDH1A3Aldehyde dehydrogenase 1 family, member A3; Belongs to the aldehyde dehydrogenase family. (475 aa)
HMGCS23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (403 aa)
COQ24-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (258 aa)
A306_00002460Isopentenyl-diphosphate Delta-isomerase 1. (227 aa)
PDSS1Prenyl (Decaprenyl) diphosphate synthase, subunit 1; Belongs to the FPP/GGPP synthase family. (339 aa)
ISPDIsoprenoid synthase domain containing. (325 aa)
PDSS2Prenyl (Decaprenyl) diphosphate synthase, subunit 2; Belongs to the FPP/GGPP synthase family. (334 aa)
ALDH8A1Aldehyde dehydrogenase 8 family, member A1; Belongs to the aldehyde dehydrogenase family. (487 aa)
GGPS1Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. (299 aa)
NUS1NUS1 dehydrodolichyl diphosphate synthase subunit. (145 aa)
DHDDSAlkyl transferase; Belongs to the UPP synthase family. (333 aa)
MVDDiphosphomevalonate decarboxylase. (356 aa)
FDPSFarnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. (304 aa)
RUSC1RUN and SH3 domain containing 1. (859 aa)
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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