16 items (Columba livia) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HSPD1	Heat shock 60kDa protein 1 (Chaperonin); Belongs to the chaperonin (HSP60) family. (567 aa)
	IL12B	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (315 aa)
	IL16	Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. (1477 aa)
	A306_00007179	Mitogen-activated protein kinase 11. (75 aa)
	A306_00007180	Mitogen-activated protein kinase. (221 aa)
	TLR3	Toll-like receptor 3; Belongs to the Toll-like receptor family. (895 aa)
	A306_00001142	Interleukin-17A. (169 aa)
	A306_00014015	Mitogen-activated protein kinase. (167 aa)
	IRF8	Interferon regulatory factor 8. (427 aa)
	TRAF6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa)
	CD40	CD40 molecule, TNF receptor superfamily member 5. (276 aa)
	A306_00000459	SCY domain-containing protein. (126 aa)
	A306_00014013	Mitogen-activated protein kinase. (182 aa)
	CCR7	Chemokine (C-C motif) receptor 7; Belongs to the G-protein coupled receptor 1 family. (373 aa)
	DUSP15-2	Interferon regulatory factor 4. (422 aa)
	TIRAP	Toll-interleukin 1 receptor (TIR) domain containing adaptor protein, transcript variant X1. (207 aa)

Your Current Organism:

Columba livia

NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A306_00000459	CCR7	A0A2I0LGD7	A0A2I0LLZ2	SCY domain-containing protein.	Chemokine (C-C motif) receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.987
A306_00001142	CD40	A0A2I0MV42	A0A2I0M270	Interleukin-17A.	CD40 molecule, TNF receptor superfamily member 5.	0.476
A306_00014013	A306_00014015	A0A2I0LKK4	R7VXR9	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.900
A306_00014015	A306_00014013	R7VXR9	A0A2I0LKK4	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.900
CCR7	A306_00000459	A0A2I0LLZ2	A0A2I0LGD7	Chemokine (C-C motif) receptor 7; Belongs to the G-protein coupled receptor 1 family.	SCY domain-containing protein.	0.987
CCR7	CD40	A0A2I0LLZ2	A0A2I0M270	Chemokine (C-C motif) receptor 7; Belongs to the G-protein coupled receptor 1 family.	CD40 molecule, TNF receptor superfamily member 5.	0.434
CD40	A306_00001142	A0A2I0M270	A0A2I0MV42	CD40 molecule, TNF receptor superfamily member 5.	Interleukin-17A.	0.476
CD40	CCR7	A0A2I0M270	A0A2I0LLZ2	CD40 molecule, TNF receptor superfamily member 5.	Chemokine (C-C motif) receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.434
CD40	TLR3	A0A2I0M270	A0A2I0MMS5	CD40 molecule, TNF receptor superfamily member 5.	Toll-like receptor 3; Belongs to the Toll-like receptor family.	0.487
CD40	TRAF6	A0A2I0M270	A0A172PWX2	CD40 molecule, TNF receptor superfamily member 5.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.930
IRF8	TIRAP	A0A2I0M0G4	A0A2I0LVG4	Interferon regulatory factor 8.	Toll-interleukin 1 receptor (TIR) domain containing adaptor protein, transcript variant X1.	0.417
TIRAP	IRF8	A0A2I0LVG4	A0A2I0M0G4	Toll-interleukin 1 receptor (TIR) domain containing adaptor protein, transcript variant X1.	Interferon regulatory factor 8.	0.417
TIRAP	TLR3	A0A2I0LVG4	A0A2I0MMS5	Toll-interleukin 1 receptor (TIR) domain containing adaptor protein, transcript variant X1.	Toll-like receptor 3; Belongs to the Toll-like receptor family.	0.796
TIRAP	TRAF6	A0A2I0LVG4	A0A172PWX2	Toll-interleukin 1 receptor (TIR) domain containing adaptor protein, transcript variant X1.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.977
TLR3	CD40	A0A2I0MMS5	A0A2I0M270	Toll-like receptor 3; Belongs to the Toll-like receptor family.	CD40 molecule, TNF receptor superfamily member 5.	0.487
TLR3	TIRAP	A0A2I0MMS5	A0A2I0LVG4	Toll-like receptor 3; Belongs to the Toll-like receptor family.	Toll-interleukin 1 receptor (TIR) domain containing adaptor protein, transcript variant X1.	0.796
TLR3	TRAF6	A0A2I0MMS5	A0A172PWX2	Toll-like receptor 3; Belongs to the Toll-like receptor family.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.972
TRAF6	CD40	A0A172PWX2	A0A2I0M270	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	CD40 molecule, TNF receptor superfamily member 5.	0.930
TRAF6	TIRAP	A0A172PWX2	A0A2I0LVG4	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	Toll-interleukin 1 receptor (TIR) domain containing adaptor protein, transcript variant X1.	0.977
TRAF6	TLR3	A0A172PWX2	A0A2I0MMS5	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	Toll-like receptor 3; Belongs to the Toll-like receptor family.	0.972