9 items (Columba livia) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SREBF2	Sterol regulatory element binding transcription factor 2. (448 aa)
	INSIG1	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (265 aa)
	A306_00000138	Uncharacterized protein. (1075 aa)
	ERLIN2	ER lipid raft associated 2. (416 aa)
	SREBF1	Sterol regulatory element binding transcription factor 1. (1025 aa)
	ERLIN1	ER lipid raft associated 1. (294 aa)
	ARHGEF10L	Rho guanine nucleotide exchange factor (GEF) 10-like. (1145 aa)
	A306_00006214	Rho guanine nucleotide exchange factor 10-like protein. (92 aa)
	INSIG2	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa)

Your Current Organism:

Columba livia

NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A306_00000138	INSIG1	A0A2I0LP57	A0A2I0MRN2	Uncharacterized protein.	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	0.827
A306_00000138	INSIG2	A0A2I0LP57	A0A2I0MGB8	Uncharacterized protein.	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	0.827
A306_00000138	SREBF1	A0A2I0LP57	A0A2I0LTK7	Uncharacterized protein.	Sterol regulatory element binding transcription factor 1.	0.951
A306_00000138	SREBF2	A0A2I0LP57	A0A2I0MJP3	Uncharacterized protein.	Sterol regulatory element binding transcription factor 2.	0.951
ERLIN1	ERLIN2	A0A2I0LX66	A0A2I0LQZ7	ER lipid raft associated 1.	ER lipid raft associated 2.	0.591
ERLIN2	ERLIN1	A0A2I0LQZ7	A0A2I0LX66	ER lipid raft associated 2.	ER lipid raft associated 1.	0.591
INSIG1	A306_00000138	A0A2I0MRN2	A0A2I0LP57	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	Uncharacterized protein.	0.827
INSIG2	A306_00000138	A0A2I0MGB8	A0A2I0LP57	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	Uncharacterized protein.	0.827
SREBF1	A306_00000138	A0A2I0LTK7	A0A2I0LP57	Sterol regulatory element binding transcription factor 1.	Uncharacterized protein.	0.951
SREBF1	SREBF2	A0A2I0LTK7	A0A2I0MJP3	Sterol regulatory element binding transcription factor 1.	Sterol regulatory element binding transcription factor 2.	0.443
SREBF2	A306_00000138	A0A2I0MJP3	A0A2I0LP57	Sterol regulatory element binding transcription factor 2.	Uncharacterized protein.	0.951
SREBF2	SREBF1	A0A2I0MJP3	A0A2I0LTK7	Sterol regulatory element binding transcription factor 2.	Sterol regulatory element binding transcription factor 1.	0.443