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PIPOX PIPOX ACLY ACLY GPAT4 GPAT4 DCAKD DCAKD AADAT AADAT DLAT DLAT HMGCS1 HMGCS1 ACSL4 ACSL4 ACSS1 ACSS1 ACOT12 ACOT12 ACSM3 ACSM3 A306_00008415 A306_00008415 A306_00008414 A306_00008414 PAPSS2 PAPSS2 DIP2A DIP2A PANK1 PANK1 ACACA ACACA MLYCD MLYCD HMGCR HMGCR FITM2 FITM2 ACSS2 ACSS2 PANK4 PANK4 ELOVL7 ELOVL7 MCCC2 MCCC2 MCEE MCEE A306_00009351 A306_00009351 NUDT19 NUDT19 MVK MVK ACACB ACACB HSD17B4 HSD17B4 SUCLG2 SUCLG2 RPP14 RPP14 PDHB PDHB PANK3 PANK3 ACSL6 ACSL6 ACSL3 ACSL3 ACOT11 ACOT11 ELOVL1 ELOVL1 ACAT1 ACAT1 HMGCS2 HMGCS2 ACSL5 ACSL5 GPAM GPAM FAR1 FAR1 AASS AASS A306_00004420 A306_00004420 FAR2 FAR2 PDHA1 PDHA1 ACOT9 ACOT9 MPC2 MPC2 PANK2 PANK2 ACSL1 ACSL1 PDHX PDHX A306_00001992 A306_00001992 A306_00002125 A306_00002125 A306_00001991 A306_00001991 DLST DLST A306_00001962 A306_00001962 CROT CROT OXSM OXSM ELOVL4 ELOVL4 ELOVL5 ELOVL5 ELOVL2 ELOVL2 TDO2 TDO2 PPCS PPCS PPCDC PPCDC PAPSS1 PAPSS1 ELOVL6 ELOVL6 A306_00015352 A306_00015352 ACOT8 ACOT8 GCDH GCDH A306_00014984 A306_00014984 NUDT8 NUDT8 ACOT7 ACOT7 MVD MVD COASY COASY
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIPOXPipecolic acid oxidase. (392 aa)
ACLYATP citrate lyase. (1068 aa)
GPAT4Glycerol-3-phosphate acyltransferase 4. (455 aa)
DCAKDDephospho-CoA kinase domain containing. (248 aa)
AADATAminoadipate aminotransferase. (425 aa)
DLATAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (548 aa)
HMGCS13-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (522 aa)
ACSL4Acyl-CoA synthetase long-chain family member 4, transcript variant X1. (711 aa)
ACSS1Acetyl-coenzyme A synthetase. (599 aa)
ACOT12Acyl-CoA thioesterase 12, transcript variant X2. (552 aa)
ACSM3Acyl-CoA synthetase medium-chain family member 3, transcript variant X1. (579 aa)
A306_00008415Acyl-coenzyme A synthetase ACSM4, mitochondrial. (579 aa)
A306_00008414Acyl-coenzyme A synthetase ACSM4, mitochondrial, transcript variant X1. (580 aa)
PAPSS23'-phosphoadenosine 5'-phosphosulfate synthase 2. (660 aa)
DIP2ADisco-interacting protein 2 homolog A. (1207 aa)
PANK1Pantothenate kinase 1, transcript variant X1. (374 aa)
ACACAAcetyl-CoA carboxylase alpha. (1676 aa)
MLYCDMalonyl-CoA decarboxylase. (474 aa)
HMGCR3-hydroxy-3-methylglutaryl coenzyme A reductase. (882 aa)
FITM2Fat storage-inducing transmembrane protein 2. (478 aa)
ACSS2Acyl-CoA synthetase short-chain family member 2. (464 aa)
PANK4Pantothenate kinase 4; Belongs to the type II pantothenate kinase family. (750 aa)
ELOVL7Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...] (279 aa)
MCCC2Methylcrotonoyl-CoA carboxylase 2 (Beta). (525 aa)
MCEEMethylmalonyl CoA epimerase. (197 aa)
A306_00009351Peroxisomal coenzyme A diphosphatase NUDT7. (259 aa)
NUDT19Nudix (Nucleoside diphosphate linked moiety X)-type motif 19. (261 aa)
MVKMevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (397 aa)
ACACBAcetyl-CoA carboxylase beta. (1345 aa)
HSD17B4Hydroxysteroid (17-beta) dehydrogenase 4. (737 aa)
SUCLG2Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (384 aa)
RPP14Ribonuclease P/MRP 14kDa subunit. (175 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (331 aa)
PANK3Pantothenate kinase 3. (355 aa)
ACSL6Acyl-CoA synthetase long-chain family member 6. (719 aa)
ACSL3Acyl-CoA synthetase long-chain family member 3, transcript variant X1. (713 aa)
ACOT11Acyl-CoA thioesterase 11. (593 aa)
ELOVL1Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (290 aa)
ACAT1Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (422 aa)
HMGCS23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (403 aa)
ACSL5Acyl-CoA synthetase long-chain family member 5, transcript variant X1. (683 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (796 aa)
FAR1Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (514 aa)
AASSAminoadipate-semialdehyde synthase, transcript variant X1. (950 aa)
A306_00004420Elongation of very long chain fatty acids protein. (265 aa)
FAR2Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (529 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (422 aa)
ACOT9Acyl-CoA thioesterase 9. (426 aa)
MPC2Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (79 aa)
PANK2Pantothenate kinase 2. (382 aa)
ACSL1Acyl-CoA synthetase long-chain family member 1. (698 aa)
PDHXDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (503 aa)
A306_00001992Acyl-coenzyme A thioesterase 1. (529 aa)
A306_00002125Acetyl-coenzyme A synthetase. (686 aa)
A306_00001991Acyl-coenzyme A thioesterase 1. (283 aa)
DLSTDihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex). (446 aa)
A306_00001962Acyl-coenzyme A thioesterase 1-like, transcript variant X2. (418 aa)
CROTCarnitine O-octanoyltransferase, transcript variant X1. (612 aa)
OXSM3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (461 aa)
ELOVL4Elongation of very long chain fatty acids protein. (272 aa)
ELOVL5Elongation of very long chain fatty acids protein. (279 aa)
ELOVL2Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production [...] (280 aa)
TDO2Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (406 aa)
PPCSPhosphopantothenoylcysteine synthetase, transcript variant X1. (138 aa)
PPCDCPhosphopantothenoylcysteine decarboxylase. (210 aa)
PAPSS13'-phosphoadenosine 5'-phosphosulfate synthase 1. (624 aa)
ELOVL6Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (300 aa)
A306_00015352Acyl-coenzyme A thioesterase 1. (181 aa)
ACOT8Uncharacterized protein. (218 aa)
GCDHGlutaryl-CoA dehydrogenase. (222 aa)
A306_00014984Acyl-coenzyme A amino acid N-acyltransferase 1. (450 aa)
NUDT8Nudix (Nucleoside diphosphate linked moiety X)-type motif 8. (140 aa)
ACOT7Acyl-CoA thioesterase 7. (263 aa)
MVDDiphosphomevalonate decarboxylase. (356 aa)
COASYCoA synthase. (303 aa)
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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