STRINGSTRING
TTC33 TTC33 NFE2L2 NFE2L2 CXCL8-3 CXCL8-3 CLGN CLGN IL-8 IL-8 UBXN4 UBXN4 ERMP1 ERMP1 NRBF2 NRBF2 ATF6 ATF6 RASGRF1 RASGRF1 FAM214A FAM214A VIMP VIMP PARP16 PARP16 PDX1 PDX1 TMCO1 TMCO1 JUN JUN RHBDD1 RHBDD1 USP13 USP13 ATF3 ATF3 CANX CANX QRICH1 QRICH1 USP19 USP19 EDEM1 EDEM1 SELENOK SELENOK TMX4 TMX4 ERLEC1 ERLEC1 DNAJB14 DNAJB14 XBP1 XBP1 FICD FICD TMED2 TMED2 UFD1 UFD1 ERN1 ERN1 PDIA3 PDIA3 A306_00006777 A306_00006777 A306_00006775 A306_00006775 VAPB VAPB CEBPB CEBPB PTPN1 PTPN1 SRPX SRPX KIAA0368 KIAA0368 PDIA4 PDIA4 PDIA2 PDIA2 HSPA5 HSPA5 UBE2J2 UBE2J2 UBE4B UBE4B FBXO2 FBXO2 FBXO6 FBXO6 RNF186 RNF186 UBXN10 UBXN10 EDEM2 EDEM2 RHBDD2 RHBDD2 DERL2 DERL2 SGTB SGTB BHLHA15 BHLHA15 GET4 GET4 AMFR AMFR YOD1 YOD1 PPP1R15B PPP1R15B RNF185 RNF185 DERL3 DERL3 FAF1 FAF1 EIF2AK2 EIF2AK2 DNAJC10 DNAJC10 DNAJB12 DNAJB12 ERLIN1 ERLIN1 ERN2 ERN2 ANKS4B ANKS4B FAF2 FAF2 TMTC3 TMTC3 RASGRF2 RASGRF2 ATG10 ATG10 UBE2G2 UBE2G2 APAF1 APAF1 HERPUD2 HERPUD2 EP300 EP300 UGGT1 UGGT1 DNAJC18 DNAJC18 CDK5RAP3 CDK5RAP3 FAM129A FAM129A EDEM3 EDEM3 ERLIN2 ERLIN2 UBE4A UBE4A CREB3L3 CREB3L3 HERPUD1 HERPUD1 EIF2B5 EIF2B5 CALR3 CALR3 BAK1 BAK1 CCDC47 CCDC47 MLXIPL MLXIPL P4HB P4HB UBXN6 UBXN6 AIFM1 AIFM1 UFC1 UFC1 MAN1B1 MAN1B1 SGTA SGTA TMEM259 TMEM259 RNF121 RNF121 AUP1 AUP1 CREB3L4 CREB3L4 HM13 HM13 VCP VCP CREB3 CREB3 SYVN1 SYVN1 FAM214B FAM214B A306_00000416 A306_00000416 FOXRED2 FOXRED2 PLA2G6 PLA2G6 TMEM67 TMEM67 DERL1 DERL1 FAM8A1 FAM8A1 MARCH6 MARCH6 RNF139 RNF139 BCL2 BCL2 ERP44 ERP44 SEC61B SEC61B NHLRC1 NHLRC1 A306_00000615 A306_00000615 PRKN PRKN UBE2J1 UBE2J1 UFL1 UFL1 NCK2 NCK2 TMTC4 TMTC4 UGGT2 UGGT2 DNAJC3 DNAJC3 UFM1 UFM1 UBA5 UBA5 STT3B STT3B TMX1 TMX1 SEL1L SEL1L CHAC1 CHAC1 THBS1 THBS1 CREB3L1 CREB3L1 JKAMP JKAMP EIF2AK4 EIF2AK4 PSMC6 PSMC6 ERO1A ERO1A EIF2S1 EIF2S1 WFS1 WFS1 SEL1L3 SEL1L3 DDRGK1 DDRGK1 EIF2AK3 EIF2AK3 CHMP3 CHMP3 RNF103 RNF103 TMEM33 TMEM33 MBTPS2 MBTPS2 HSP90B1 HSP90B1 CREB3L2 CREB3L2 ERP27 ERP27 TMEM117 TMEM117 ATF4 ATF4 DNAJB9 DNAJB9 CFTR CFTR A306_00004891 A306_00004891
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TTC33Tetratricopeptide repeat domain 33. (261 aa)
NFE2L2Nuclear factor, erythroid 2-like 2. (582 aa)
CXCL8-3Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (156 aa)
CLGNCalmegin. (613 aa)
IL-8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (103 aa)
UBXN4UBX domain protein 4. (476 aa)
ERMP1Endoplasmic reticulum metallopeptidase 1. (485 aa)
NRBF2Nuclear receptor binding factor 2. (300 aa)
ATF6Activating transcription factor 6. (477 aa)
RASGRF1Ras protein-specific guanine nucleotide-releasing factor 1. (1257 aa)
FAM214AFamily with sequence similarity 214, member A. (1090 aa)
VIMPVCP-interacting membrane selenoprotein. (119 aa)
PARP16Poly [ADP-ribose] polymerase. (361 aa)
PDX1Pancreatic and duodenal homeobox 1. (358 aa)
TMCO1Calcium load-activated calcium channel; Calcium-selective channel required to prevent calcium stores from overfilling. (188 aa)
JUNJun proto-oncogene; Belongs to the bZIP family. (338 aa)
RHBDD1Rhomboid domain containing 1. (314 aa)
USP13Ubiquitin carboxyl-terminal hydrolase. (801 aa)
ATF3Activating transcription factor 3, transcript variant X1. (218 aa)
CANXCalnexin. (599 aa)
QRICH1Glutamine-rich 1. (771 aa)
USP19Ubiquitin specific peptidase 19; Belongs to the peptidase C19 family. (679 aa)
EDEM1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (456 aa)
SELENOKSelenoprotein K. (100 aa)
TMX4Thioredoxin-related transmembrane protein 4. (290 aa)
ERLEC1Endoplasmic reticulum lectin 1. (479 aa)
DNAJB14DnaJ (Hsp40) homolog, subfamily B, member 14. (330 aa)
XBP1X-box binding protein 1. (197 aa)
FICDFIC domain containing. (455 aa)
TMED2Transmembrane p24 trafficking protein 2, transcript variant X1. (123 aa)
UFD1Uncharacterized protein. (307 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1, transcript variant X1. (804 aa)
PDIA3Protein disulfide-isomerase. (463 aa)
A306_00006777Protein PML. (739 aa)
A306_00006775Protein PML. (586 aa)
VAPBVAMP (Vesicle-associated membrane protein)-associated protein B and C. (222 aa)
CEBPBCCAAT/enhancer binding protein (C/EBP), beta. (218 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (354 aa)
SRPXSushi-repeat containing protein, X-linked. (494 aa)
KIAA0368KIAA0368 ortholog. (1652 aa)
PDIA4Protein disulfide-isomerase. (615 aa)
PDIA2Protein disulfide isomerase family A, member 2. (512 aa)
HSPA5Heat shock 70kDa protein 5 (Glucose-regulated protein, 78kDa); Belongs to the heat shock protein 70 family. (603 aa)
UBE2J2Ubiquitin-conjugating enzyme E2, J2. (259 aa)
UBE4BUbiquitination factor E4B. (1284 aa)
FBXO2F-box protein 2. (244 aa)
FBXO6F-box protein 6. (254 aa)
RNF186Ring finger protein 186. (337 aa)
UBXN10UBX domain protein 10. (293 aa)
EDEM2alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (534 aa)
RHBDD2Rhomboid domain containing 2. (357 aa)
DERL2Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (255 aa)
SGTBSmall glutamine-rich tetratricopeptide repeat (TPR)-containing, beta. (304 aa)
BHLHA15Basic helix-loop-helix family, member a15, transcript variant X1. (166 aa)
GET4Golgi to ER traffic protein 4, transcript variant X1. (274 aa)
AMFRAutocrine motility factor receptor, E3 ubiquitin protein ligase. (549 aa)
YOD1YOD1 deubiquitinase. (211 aa)
PPP1R15BProtein phosphatase 1, regulatory subunit 15B. (517 aa)
RNF185Ring finger protein 185. (194 aa)
DERL3Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (216 aa)
FAF1Fas (TNFRSF6) associated factor 1. (733 aa)
EIF2AK2Eukaryotic translation initiation factor 2-alpha kinase 2. (609 aa)
DNAJC10DnaJ (Hsp40) homolog, subfamily C, member 10. (832 aa)
DNAJB12DnaJ (Hsp40) homolog, subfamily B, member 12. (346 aa)
ERLIN1ER lipid raft associated 1. (294 aa)
ERN2Endoplasmic reticulum to nucleus signaling 2. (850 aa)
ANKS4BAnkyrin repeat and sterile alpha motif domain containing 4B. (412 aa)
FAF2Fas associated factor family member 2. (425 aa)
TMTC3Transmembrane and tetratricopeptide repeat containing 3. (917 aa)
RASGRF2Ras protein-specific guanine nucleotide-releasing factor 2. (1238 aa)
ATG10Autophagy related 10. (229 aa)
UBE2G2Ubiquitin-conjugating enzyme E2G 2, transcript variant X1; Belongs to the ubiquitin-conjugating enzyme family. (142 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa)
HERPUD2HERPUD family member 2, transcript variant X1. (406 aa)
EP300E1A binding protein p300. (2044 aa)
UGGT1UDP-glucose glycoprotein glucosyltransferase 1, transcript variant X1. (1531 aa)
DNAJC18DnaJ (Hsp40) homolog, subfamily C, member 18. (189 aa)
CDK5RAP3CDK5 regulatory subunit associated protein 3. (199 aa)
FAM129AFamily with sequence similarity 129, member A. (1139 aa)
EDEM3alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (763 aa)
ERLIN2ER lipid raft associated 2. (416 aa)
UBE4AUbiquitination factor E4A. (941 aa)
CREB3L3cAMP responsive element binding protein 3-like 3. (395 aa)
HERPUD1Homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1. (382 aa)
EIF2B5Eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa. (653 aa)
CALR3Calreticulin. (449 aa)
BAK1BCL2-antagonist/killer 1. (217 aa)
CCDC47Coiled-coil domain containing 47. (481 aa)
MLXIPLMLX interacting protein-like. (731 aa)
P4HBProtein disulfide-isomerase. (424 aa)
UBXN6UBX domain protein 6, transcript variant X1. (354 aa)
AIFM1Apoptosis-inducing factor, mitochondrion-associated, 1. (443 aa)
UFC1Ubiquitin-fold modifier conjugating enzyme 1. (91 aa)
MAN1B1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (579 aa)
SGTASmall glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha. (275 aa)
TMEM259Transmembrane protein 259. (531 aa)
RNF121Ring finger protein 121. (266 aa)
AUP1Ancient ubiquitous protein 1. (529 aa)
CREB3L4cAMP responsive element binding protein 3-like 4. (178 aa)
HM13Uncharacterized protein. (268 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (876 aa)
CREB3cAMP responsive element binding protein 3. (438 aa)
SYVN1E3 ubiquitin-protein ligase synoviolin. (269 aa)
FAM214BUncharacterized protein. (424 aa)
A306_00000416Uncharacterized protein. (123 aa)
FOXRED2FAD-dependent oxidoreductase domain-containing protein 2. (685 aa)
PLA2G6Phospholipase A2, group VI (Cytosolic, calcium-independent), transcript variant X1. (805 aa)
TMEM67Transmembrane protein 67. (910 aa)
DERL1Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (214 aa)
FAM8A1Family with sequence similarity 8, member A1. (199 aa)
MARCH6Membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase. (903 aa)
RNF139Ring finger protein 139. (614 aa)
BCL2B-cell CLL/lymphoma 2. (138 aa)
ERP44Endoplasmic reticulum protein 44. (344 aa)
SEC61BSec61 translocon beta subunit. (98 aa)
NHLRC1NHL repeat containing E3 ubiquitin protein ligase 1. (319 aa)
A306_00000615RBR-type E3 ubiquitin transferase. (233 aa)
PRKNE3 ubiquitin-protein ligase parkin. (292 aa)
UBE2J1Ubiquitin-conjugating enzyme E2, J1. (315 aa)
UFL1UFM1-specific ligase 1. (865 aa)
NCK2Cytoplasmic protein. (380 aa)
TMTC4Transmembrane and tetratricopeptide repeat containing 4. (740 aa)
UGGT2UDP-glucose glycoprotein glucosyltransferase 2. (1581 aa)
DNAJC3DnaJ (Hsp40) homolog, subfamily C, member 3. (462 aa)
UFM1Ubiquitin-fold modifier 1; Ubiquitin-like modifier which can be covalently attached to substrate proteins as a monomer or a lysine-linked polymer in a post- translational process called ufmylation. Ufmylation on lysine residues of proteins may play a crucial role in a number of cellular processes. (85 aa)
UBA5Ubiquitin-like modifier activating enzyme 5. (362 aa)
STT3BSTT3B, subunit of the oligosaccharyltransferase complex (Catalytic). (708 aa)
TMX1Thioredoxin-related transmembrane protein 1. (273 aa)
SEL1LFibronectin type-II domain-containing protein. (784 aa)
CHAC1Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (120 aa)
THBS1Thrombospondin 1. (997 aa)
CREB3L1cAMP responsive element binding protein 3-like 1. (458 aa)
JKAMPJNK1/MAPK8-associated membrane protein. (248 aa)
EIF2AK4Eukaryotic translation initiation factor 2 alpha kinase 4. (1683 aa)
PSMC6Proteasome (Prosome, macropain) 26S subunit, ATPase, 6; Belongs to the AAA ATPase family. (369 aa)
ERO1AEndoplasmic reticulum oxidoreductase alpha. (246 aa)
EIF2S1Eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa. (315 aa)
WFS1Wolfram syndrome 1 (Wolframin). (293 aa)
SEL1L3Uncharacterized protein. (1064 aa)
DDRGK1DDRGK domain containing 1. (242 aa)
EIF2AK3Eukaryotic translation initiation factor 2-alpha kinase 3. (1004 aa)
CHMP3Charged multivesicular body protein 3. (192 aa)
RNF103Ring finger protein 103. (479 aa)
TMEM33Transmembrane protein 33. (229 aa)
MBTPS2Membrane-bound transcription factor peptidase, site 2. (481 aa)
HSP90B1Heat shock protein 90kDa beta (Grp94), member 1. (876 aa)
CREB3L2cAMP responsive element binding protein 3-like 2. (456 aa)
ERP27Endoplasmic reticulum protein 27. (280 aa)
TMEM117Transmembrane protein 117. (512 aa)
ATF4Activating transcription factor 4. (354 aa)
DNAJB9DnaJ (Hsp40) homolog, subfamily B, member 9, transcript variant X1. (215 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1485 aa)
A306_00004891Histone acetyltransferase p300-like. (94 aa)
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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