24 items (Columba livia) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TERT	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1257 aa)
	SIRT6	Sirtuin 6. (340 aa)
	CAPN10	Calpain 10; Belongs to the peptidase C2 family. (671 aa)
	ASPSCR1	Alveolar soft part sarcoma chromosome region, candidate 1. (496 aa)
	PEA15	Phosphoprotein enriched in astrocytes 15. (158 aa)
	OCLN	Occludin. (375 aa)
	OSTN	Osteocrin, transcript variant X1. (133 aa)
	APPL1	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1. (704 aa)
	ADIPOQ	Adiponectin, C1Q and collagen domain containing. (245 aa)
	OSBPL8	Oxysterol-binding protein; Belongs to the OSBP family. (891 aa)
	FAM132A	Family with sequence similarity 132, member A. (321 aa)
	GPR50	G protein-coupled receptor 50; Belongs to the G-protein coupled receptor 1 family. (299 aa)
	PID1	Phosphotyrosine interaction domain containing 1. (203 aa)
	RNASEL	Ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent). (701 aa)
	MEF2A	Myocyte enhancer factor 2A, transcript variant X1. (541 aa)
	STXBP3	Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (594 aa)
	FGF19	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (170 aa)
	PTH	Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (119 aa)
	NFE2L2	Nuclear factor, erythroid 2-like 2. (582 aa)
	APPL2	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2. (495 aa)
	CREBL2	cAMP responsive element binding protein-like 2, transcript variant X1. (144 aa)
	MTNR1A	Melatonin receptor 1A; Belongs to the G-protein coupled receptor 1 family. (376 aa)
	SLC1A2	Amino acid transporter. (563 aa)
	OPN3	Opsin 3. (395 aa)

Your Current Organism:

Columba livia

NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADIPOQ	APPL1	A0A2I0LW41	A0A2I0LUC8	Adiponectin, C1Q and collagen domain containing.	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.	0.681
ADIPOQ	APPL2	A0A2I0LW41	A0A2I0MK58	Adiponectin, C1Q and collagen domain containing.	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2.	0.681
APPL1	ADIPOQ	A0A2I0LUC8	A0A2I0LW41	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.	Adiponectin, C1Q and collagen domain containing.	0.681
APPL1	APPL2	A0A2I0LUC8	A0A2I0MK58	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2.	0.984
APPL1	PEA15	A0A2I0LUC8	A0A2I0LLT8	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.	Phosphoprotein enriched in astrocytes 15.	0.669
APPL2	ADIPOQ	A0A2I0MK58	A0A2I0LW41	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2.	Adiponectin, C1Q and collagen domain containing.	0.681
APPL2	APPL1	A0A2I0MK58	A0A2I0LUC8	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2.	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.	0.984
APPL2	PEA15	A0A2I0MK58	A0A2I0LLT8	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2.	Phosphoprotein enriched in astrocytes 15.	0.669
FGF19	PTH	A0A2I0MHQ5	A0A2I0MI25	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family.	0.412
GPR50	MTNR1A	A0A2I0MAZ8	A0A2I0MMT6	G protein-coupled receptor 50; Belongs to the G-protein coupled receptor 1 family.	Melatonin receptor 1A; Belongs to the G-protein coupled receptor 1 family.	0.901
MTNR1A	GPR50	A0A2I0MMT6	A0A2I0MAZ8	Melatonin receptor 1A; Belongs to the G-protein coupled receptor 1 family.	G protein-coupled receptor 50; Belongs to the G-protein coupled receptor 1 family.	0.901
NFE2L2	RNASEL	A0A2I0MIX9	A0A2I0MBT5	Nuclear factor, erythroid 2-like 2.	Ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent).	0.401
PEA15	APPL1	A0A2I0LLT8	A0A2I0LUC8	Phosphoprotein enriched in astrocytes 15.	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.	0.669
PEA15	APPL2	A0A2I0LLT8	A0A2I0MK58	Phosphoprotein enriched in astrocytes 15.	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2.	0.669
PTH	FGF19	A0A2I0MI25	A0A2I0MHQ5	Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.412
RNASEL	NFE2L2	A0A2I0MBT5	A0A2I0MIX9	Ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent).	Nuclear factor, erythroid 2-like 2.	0.401