39 items (Columba livia) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	A306_00004324	Dimethylaniline monooxygenase [N-oxide-forming]. (543 aa)
	FMO4	Dimethylaniline monooxygenase [N-oxide-forming]. (546 aa)
	CRYZ	Crystallin, zeta (Quinone reductase). (329 aa)
	DPYD	Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (1049 aa)
	DHCR7	7-dehydrocholesterol reductase. (475 aa)
	CAT	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (528 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (327 aa)
	QDPR	Quinoid dihydropteridine reductase. (186 aa)
	HIBADH	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (301 aa)
	TP53I3	Tumor protein p53 inducible protein 3, transcript variant X1. (351 aa)
	DECR1	2,4-dienoyl CoA reductase 1, mitochondrial. (331 aa)
	GMDS	GDP-mannose 4,6-dehydratase. (367 aa)
	MTRR	5-methyltetrahydrofolate-homocysteine methyltransferase reductase. (393 aa)
	A306_00001737	Methionine synthase reductase-like. (91 aa)
	GRHPR	Glyoxylate reductase/hydroxypyruvate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (264 aa)
	A306_00000347	Aldo_ket_red domain-containing protein. (173 aa)
	A306_00014490	Nitric oxide synthase, endothelial. (507 aa)
	DHFR	Dihydrofolate reductase. (153 aa)
	A306_00013618	Putative 2-ketogluconate reductase, transcript variant X1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (433 aa)
	A306_00013619	Putative 2-ketogluconate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (327 aa)
	CBR4	Carbonyl reductase 4. (237 aa)
	A306_00000217	Uncharacterized protein. (429 aa)
	GSR	Glutathione reductase. (459 aa)
	H6PD	Hexose-6-phosphate dehydrogenase (Glucose 1-dehydrogenase). (767 aa)
	POR	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (677 aa)
	KCNAB1	Potassium channel, voltage gated subfamily A regulatory beta subunit 1, transcript variant X1. (418 aa)
	HMGCR	3-hydroxy-3-methylglutaryl coenzyme A reductase. (882 aa)
	ME3	Malic enzyme. (542 aa)
	HSD11B1	Corticosteroid 11-beta-dehydrogenase isozyme 1-like. (229 aa)
	A306_00007422	Corticosteroid 11-beta-dehydrogenase isozyme 1. (422 aa)
	NOS1	Nitric oxide synthase 1 (Neuronal). (1438 aa)
	NOS2	Nitric oxide synthase 2, inducible. (944 aa)
	GLYR1	PWWP domain-containing protein. (576 aa)
	CRYM	Crystallin, mu. (351 aa)
	PGD	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (470 aa)
	LBR	Lamin B receptor. (608 aa)
	DUS2	Dihydrouridine synthase 2. (443 aa)
	A306_00004325	Dimethylaniline monooxygenase [N-oxide-forming]. (580 aa)
	FMO1	Dimethylaniline monooxygenase [N-oxide-forming]. (530 aa)

Your Current Organism:

Columba livia

NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A306_00000217	A306_00014490	A0A2I0LMD7	A0A2I0LJM0	Uncharacterized protein.	Nitric oxide synthase, endothelial.	0.464
A306_00001737	CAT	A0A2I0MXH7	A0A2I0MHZ3	Methionine synthase reductase-like.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	0.423
A306_00001737	MTRR	A0A2I0MXH7	A0A2I0MXH1	Methionine synthase reductase-like.	5-methyltetrahydrofolate-homocysteine methyltransferase reductase.	0.899
A306_00004324	FMO1	A0A2I0MC12	A0A2I0MC24	Dimethylaniline monooxygenase [N-oxide-forming].	Dimethylaniline monooxygenase [N-oxide-forming].	0.902
A306_00004324	FMO4	A0A2I0MC12	A0A2I0MC26	Dimethylaniline monooxygenase [N-oxide-forming].	Dimethylaniline monooxygenase [N-oxide-forming].	0.902
A306_00007422	H6PD	A0A2I0M001	A0A2I0M2Z4	Corticosteroid 11-beta-dehydrogenase isozyme 1.	Hexose-6-phosphate dehydrogenase (Glucose 1-dehydrogenase).	0.500
A306_00007422	HSD11B1	A0A2I0M001	A0A2I0M006	Corticosteroid 11-beta-dehydrogenase isozyme 1.	Corticosteroid 11-beta-dehydrogenase isozyme 1-like.	0.901
A306_00013618	GAPDH	A0A2I0LSX8	A0A2I0MLP3	Putative 2-ketogluconate reductase, transcript variant X1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.741
A306_00013618	GSR	A0A2I0LSX8	A0A2I0LMD6	Putative 2-ketogluconate reductase, transcript variant X1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Glutathione reductase.	0.430
A306_00013618	H6PD	A0A2I0LSX8	A0A2I0M2Z4	Putative 2-ketogluconate reductase, transcript variant X1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Hexose-6-phosphate dehydrogenase (Glucose 1-dehydrogenase).	0.731
A306_00013619	GAPDH	A0A2I0LSW4	A0A2I0MLP3	Putative 2-ketogluconate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.741
A306_00013619	GSR	A0A2I0LSW4	A0A2I0LMD6	Putative 2-ketogluconate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Glutathione reductase.	0.430
A306_00013619	H6PD	A0A2I0LSW4	A0A2I0M2Z4	Putative 2-ketogluconate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Hexose-6-phosphate dehydrogenase (Glucose 1-dehydrogenase).	0.731
A306_00014490	A306_00000217	A0A2I0LJM0	A0A2I0LMD7	Nitric oxide synthase, endothelial.	Uncharacterized protein.	0.464
A306_00014490	CAT	A0A2I0LJM0	A0A2I0MHZ3	Nitric oxide synthase, endothelial.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	0.423
A306_00014490	MTRR	A0A2I0LJM0	A0A2I0MXH1	Nitric oxide synthase, endothelial.	5-methyltetrahydrofolate-homocysteine methyltransferase reductase.	0.500
CAT	A306_00001737	A0A2I0MHZ3	A0A2I0MXH7	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Methionine synthase reductase-like.	0.423
CAT	A306_00014490	A0A2I0MHZ3	A0A2I0LJM0	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Nitric oxide synthase, endothelial.	0.423
CAT	GSR	A0A2I0MHZ3	A0A2I0LMD6	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Glutathione reductase.	0.727
CAT	H6PD	A0A2I0MHZ3	A0A2I0M2Z4	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Hexose-6-phosphate dehydrogenase (Glucose 1-dehydrogenase).	0.751