STRINGSTRING
A306_00015291 A306_00015291 FCHSD1 FCHSD1 A306_00000386 A306_00000386 A306_00000390 A306_00000390 ARFIP2 ARFIP2 A306_00000182 A306_00000182 TESK1 TESK1 A306_00000398 A306_00000398 A306_00000216 A306_00000216 LIMK1 LIMK1 A306_00015009 A306_00015009 A306_00014930 A306_00014930 A306_00000324 A306_00000324 ARPC4 ARPC4 GBA2 GBA2 ARPC2 ARPC2 A306_00015227 A306_00015227 A306_00000103 A306_00000103 A306_00014690 A306_00014690 ARHGAP35 ARHGAP35 RAPGEF3 RAPGEF3 DBNL DBNL CAPG CAPG VIL1 VIL1 WASF2 WASF2 TMOD4 TMOD4 KANK3 KANK3 F11R F11R NF2 NF2 RLTPR RLTPR FHOD1 FHOD1 A306_00014192 A306_00014192 ADD2 ADD2 SSH2 SSH2 BAIAP2 BAIAP2 ASAP3 ASAP3 MYADM MYADM A306_00013140 A306_00013140 ARHGEF18 ARHGEF18 APOA1 APOA1 CDC42 CDC42 A306_00012717 A306_00012717 CAPZA3 CAPZA3 PAK3 PAK3 ESAM ESAM ARF6 ARF6 TWF2 TWF2 PRKCD PRKCD FLII FLII RICTOR RICTOR PTGER4 PTGER4 GMFB GMFB PAK2 PAK2 DSTN DSTN RASA1 RASA1 CYFIP2 CYFIP2 MLST8 MLST8 KANK1 KANK1 ARFIP1 ARFIP1 CDC42EP3 CDC42EP3 A306_00008069 A306_00008069 PPM1E PPM1E CIT CIT A306_00011355 A306_00011355 CLASP2 CLASP2 CAPZA1 CAPZA1 LMOD1 LMOD1 COTL1 COTL1 ARPC1A ARPC1A ARPC1B ARPC1B BAIAP2L1 BAIAP2L1 PFN2 PFN2 INPP5K INPP5K A306_00008521 A306_00008521 HSPB1 HSPB1 SERPINF2 SERPINF2 ARHGAP40 ARHGAP40 WNT11 WNT11 PAK1 PAK1 FCHSD2 FCHSD2 PLEKHB1 PLEKHB1 MTOR MTOR ARHGEF10L ARHGEF10L A306_00006214 A306_00006214 CAPZB CAPZB TSC1 TSC1 SPTAN1 SPTAN1 GSN GSN TMSB15B TMSB15B FRMD7 FRMD7 TGFBR1 TGFBR1 PFN3 PFN3 LPAR1 LPAR1 CUNH9orf72 CUNH9orf72 CGNL1 CGNL1 BBS4 BBS4 CDC42EP4 CDC42EP4 RHPN2 RHPN2 PPM1F PPM1F HIP1R HIP1R ARPC3 ARPC3 SSH1 SSH1 AP1AR AP1AR SPTBN1 SPTBN1 MKKS MKKS LMOD3 LMOD3 A306_00007271 A306_00007271 SYNPO SYNPO PLEKHH2 PLEKHH2 TENM1 TENM1 A306_00007595 A306_00007595 PIK3CA PIK3CA TACSTD2 TACSTD2 ARPC5 ARPC5 KANK4 KANK4 MYOC MYOC WASF3 WASF3 RDX RDX WHAMM WHAMM A306_00005488 A306_00005488 A306_00005489 A306_00005489 WDR63 WDR63 ADD3 ADD3 SYNPO2L SYNPO2L CLASP1 CLASP1 SYNPO2 SYNPO2 PRKCQ PRKCQ TMEFF2 TMEFF2 XIRP2 XIRP2 NCKAP1 NCKAP1 WASL WASL MET MET CAPZA2 CAPZA2 TWF1 TWF1 BAIAP2L2 BAIAP2L2 LMOD2 LMOD2 SH3BP1 SH3BP1 ARHGEF5 ARHGEF5 MTPN MTPN TMSB4X TMSB4X ARHGAP6 ARHGAP6 CYFIP1 CYFIP1 EPHA1 EPHA1 LIMCH1 LIMCH1 A306_00003537 A306_00003537 ADD1 ADD1 WDR1 WDR1 ALMS1 ALMS1 SLIT2 SLIT2 EVL EVL GPR65 GPR65 SPTBN5 SPTBN5 TTC8 TTC8 SCIN SCIN SVIL SVIL VILL VILL TGFBR2 TGFBR2 NCK2 NCK2 ARHGEF10 ARHGEF10 FAM49A FAM49A SNX9 SNX9 PFN4 PFN4 WASF1 WASF1 ROCK2 ROCK2 ITGB1BP1 ITGB1BP1 PRKN PRKN A306_00000615 A306_00000615 LATS1 LATS1 ARHGAP18 ARHGAP18 CTGF CTGF A306_00000762 A306_00000762 A306_00001420 A306_00001420 LRRC16A LRRC16A MTSS1 MTSS1 WASHC5 WASHC5 FAM49B FAM49B FHOD3 FHOD3 ARHGAP28 ARHGAP28 FAM206A FAM206A ARFGEF1 ARFGEF1 RHPN1 RHPN1 CDC42EP1 CDC42EP1 PICK1 PICK1 TMOD1 TMOD1 CUNH15orf62 CUNH15orf62 S100A10 S100A10 PLEK PLEK A306_00013344 A306_00013344
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A306_00015291Rap guanine nucleotide exchange factor 3. (86 aa)
FCHSD1F-BAR domain-containing protein. (338 aa)
A306_00000386Protein kinase domain-containing protein. (155 aa)
A306_00000390Uncharacterized protein. (258 aa)
ARFIP2ADP-ribosylation factor interacting protein 2. (195 aa)
A306_00000182Uncharacterized protein. (826 aa)
TESK1Uncharacterized protein. (416 aa)
A306_00000398Calponin-homology (CH) domain-containing protein. (115 aa)
A306_00000216HP domain-containing protein. (448 aa)
LIMK1Uncharacterized protein. (351 aa)
A306_00015009Spectrin beta chain, non-erythrocytic 4. (933 aa)
A306_00014930Proline-, glutamic acid-and leucine-rich protein 1-like. (141 aa)
A306_00000324PH domain-containing protein. (473 aa)
ARPC4Actin related protein 2/3 complex, subunit 4, 20kDa. (78 aa)
GBA2Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. (820 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (277 aa)
A306_00015227C-C motif chemokine 21. (115 aa)
A306_00000103Uncharacterized protein. (409 aa)
A306_00014690Nck-associated protein 1-like. (983 aa)
ARHGAP35Rho GTPase activating protein 35. (630 aa)
RAPGEF3Rap guanine nucleotide exchange factor (GEF) 3. (710 aa)
DBNLDrebrin-like. (537 aa)
CAPGCapping protein (Actin filament), gelsolin-like. (270 aa)
VIL1Villin 1. (839 aa)
WASF2WAS protein family, member 2. (252 aa)
TMOD4Tropomodulin 4 (Muscle). (305 aa)
KANK3KN motif and ankyrin repeat domains 3. (369 aa)
F11RF11 receptor. (267 aa)
NF2Neurofibromin 2 (Merlin). (592 aa)
RLTPRRGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing. (1545 aa)
FHOD1Uncharacterized protein. (916 aa)
A306_00014192Hematopoietic lineage cell-specific protein. (331 aa)
ADD2Adducin 2 (Beta). (566 aa)
SSH2Slingshot protein phosphatase 2. (1418 aa)
BAIAP2BAI1-associated protein 2. (493 aa)
ASAP3ArfGAP with SH3 domain, ankyrin repeat and PH domain 3. (430 aa)
MYADMMyeloid-associated differentiation marker. (299 aa)
A306_00013140LIM domain and actin-binding protein 1. (624 aa)
ARHGEF18Rho/Rac guanine nucleotide exchange factor (GEF) 18. (812 aa)
APOA1Apolipoprotein A-I. (264 aa)
CDC42Cell division cycle 42, transcript variant X2. (191 aa)
A306_00012717Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (297 aa)
CAPZA3F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (291 aa)
PAK3Non-specific serine/threonine protein kinase. (543 aa)
ESAMEndothelial cell-selective adhesion molecule. (335 aa)
ARF6ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (216 aa)
TWF2Twinfilin actin binding protein 2. (351 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (685 aa)
FLIIFlightless I actin binding protein. (1248 aa)
RICTORRPTOR independent companion of MTOR, complex 2. (1676 aa)
PTGER4Prostaglandin E receptor 4 (Subtype EP4); Belongs to the G-protein coupled receptor 1 family. (505 aa)
GMFBGlia maturation factor, beta. (83 aa)
PAK2Non-specific serine/threonine protein kinase. (525 aa)
DSTNDestrin (Actin depolymerizing factor), transcript variant X1; Belongs to the actin-binding proteins ADF family. (165 aa)
RASA1RAS p21 protein activator (GTPase activating protein) 1. (982 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
MLST8MTOR associated protein, LST8 homolog. (271 aa)
KANK1KN motif and ankyrin repeat domains 1. (692 aa)
ARFIP1ADP-ribosylation factor interacting protein 1, transcript variant X1. (413 aa)
CDC42EP3CDC42 effector protein (Rho GTPase binding) 3. (254 aa)
A306_00008069Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (322 aa)
PPM1EProtein phosphatase, Mg2+/Mn2+ dependent, 1E. (652 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2070 aa)
A306_00011355CLIP-associating protein 1-like. (193 aa)
CLASP2Cytoplasmic linker associated protein 2, transcript variant X1. (1276 aa)
CAPZA1F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (139 aa)
LMOD1Leiomodin 1 (Smooth muscle). (626 aa)
COTL1Coactosin-like F-actin binding protein 1. (142 aa)
ARPC1AActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (370 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (369 aa)
BAIAP2L1BAI1-associated protein 2-like 1. (504 aa)
PFN2Profilin; Belongs to the profilin family. (245 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (417 aa)
A306_00008521Merlin. (647 aa)
HSPB1Heat shock 27kDa protein 1; Belongs to the small heat shock protein (HSP20) family. (189 aa)
SERPINF2Alpha-2-antiplasmin isoform X1; Belongs to the serpin family. (526 aa)
ARHGAP40Rho GTPase activating protein 40. (666 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
FCHSD2FCH and double SH3 domains 2. (694 aa)
PLEKHB1Pleckstrin homology domain containing, family B (Evectins) member 1. (243 aa)
MTORSerine/threonine-protein kinase TOR. (1875 aa)
ARHGEF10LRho guanine nucleotide exchange factor (GEF) 10-like. (1145 aa)
A306_00006214Rho guanine nucleotide exchange factor 10-like protein. (92 aa)
CAPZBF-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (282 aa)
TSC1Tuberous sclerosis 1, transcript variant X1. (1157 aa)
SPTAN1Spectrin, alpha, non-erythrocytic 1, transcript variant X1. (2533 aa)
GSNGelsolin. (778 aa)
TMSB15BThymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (45 aa)
FRMD7FERM domain containing 7. (336 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
PFN3Profilin; Belongs to the profilin family. (134 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (367 aa)
CUNH9orf72Uncharacterized protein. (487 aa)
CGNL1Cingulin-like 1, transcript variant X1. (1291 aa)
BBS4Bardet-Biedl syndrome 4. (565 aa)
CDC42EP4CDC42 effector protein (Rho GTPase binding) 4. (289 aa)
RHPN2Rhophilin, Rho GTPase binding protein 2. (631 aa)
PPM1FProtein phosphatase, Mg2+/Mn2+ dependent, 1F. (416 aa)
HIP1RHuntingtin interacting protein 1 related. (803 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
SSH1Slingshot protein phosphatase 1. (583 aa)
AP1ARAdaptor-related protein complex 1 associated regulatory protein. (300 aa)
SPTBN1Spectrin, beta, non-erythrocytic 1. (936 aa)
MKKSMcKusick-Kaufman syndrome, transcript variant X1. (572 aa)
LMOD3Leiomodin 3 (Fetal). (569 aa)
A306_00007271Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (45 aa)
SYNPOSynaptopodin. (909 aa)
PLEKHH2Pleckstrin homology domain containing, family H (With MyTH4 domain) member 2. (1499 aa)
TENM1Teneurin transmembrane protein 1. (2354 aa)
A306_00007595Wiskott-Aldrich syndrome protein family member 3-like. (414 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1052 aa)
TACSTD2Tumor-associated calcium signal transducer 2. (65 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (166 aa)
KANK4KN motif and ankyrin repeat domains 4. (986 aa)
MYOCMyocilin, trabecular meshwork inducible glucocorticoid response. (410 aa)
WASF3WAS protein family, member 3. (410 aa)
RDXRadixin. (576 aa)
WHAMMWAS protein homolog associated with actin, golgi membranes and microtubules. (485 aa)
A306_00005488Tropomodulin-3. (351 aa)
A306_00005489Tropomodulin-2. (351 aa)
WDR63WD repeat domain 63. (865 aa)
ADD3Adducin 3 (Gamma), transcript variant X1. (709 aa)
SYNPO2LSynaptopodin 2-like. (1085 aa)
CLASP1Cytoplasmic linker associated protein 1, transcript variant X1. (1496 aa)
SYNPO2Synaptopodin 2. (1274 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (732 aa)
TMEFF2Transmembrane protein with EGF-like and two follistatin-like domains 2. (425 aa)
XIRP2Xin actin binding repeat containing 2. (606 aa)
NCKAP1NCK-associated protein 1. (1028 aa)
WASLWiskott-Aldrich syndrome-like, transcript variant X1. (456 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1382 aa)
CAPZA2F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (282 aa)
TWF1Twinfilin actin binding protein 1. (456 aa)
BAIAP2L2BAI1-associated protein 2-like 2. (495 aa)
LMOD2Leiomodin 2 (Cardiac). (471 aa)
SH3BP1SH3-domain binding protein 1. (633 aa)
ARHGEF5Rho guanine nucleotide exchange factor (GEF) 5. (1665 aa)
MTPNMyotrophin. (118 aa)
TMSB4XThymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (44 aa)
ARHGAP6Rho GTPase activating protein 6. (781 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
EPHA1EPH receptor A1. (1036 aa)
LIMCH1LIM and calponin homology domains 1, transcript variant X1. (1582 aa)
A306_00003537KIAA1211 ortholog. (1304 aa)
ADD1Adducin 1 (Alpha), transcript variant X1. (767 aa)
WDR1WD repeat domain 1. (620 aa)
ALMS1Alstrom syndrome protein 1. (1560 aa)
SLIT2Slit guidance ligand 2. (1359 aa)
EVLEnah/Vasp-like. (676 aa)
GPR65G protein-coupled receptor 65; Belongs to the G-protein coupled receptor 1 family. (382 aa)
SPTBN5Spectrin, beta, non-erythrocytic 5. (3874 aa)
TTC8Tetratricopeptide repeat domain 8, transcript variant X1. (455 aa)
SCINScinderin. (672 aa)
SVILSupervillin, transcript variant X1. (2262 aa)
VILLVillin-like. (559 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (633 aa)
NCK2Cytoplasmic protein. (380 aa)
ARHGEF10Rho guanine nucleotide exchange factor (GEF) 10. (1354 aa)
FAM49AFamily with sequence similarity 49, member A, transcript variant X1. (323 aa)
SNX9Sorting nexin. (599 aa)
PFN4Uncharacterized protein; Belongs to the profilin family. (108 aa)
WASF1WAS protein family, member 1. (507 aa)
ROCK2Rho-associated, coiled-coil containing protein kinase 2, transcript variant X1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1356 aa)
ITGB1BP1Integrin beta 1 binding protein 1, transcript variant X1. (200 aa)
PRKNE3 ubiquitin-protein ligase parkin. (292 aa)
A306_00000615RBR-type E3 ubiquitin transferase. (233 aa)
LATS1Large tumor suppressor kinase 1, transcript variant X1. (1139 aa)
ARHGAP18Rho GTPase activating protein 18. (312 aa)
CTGFConnective tissue growth factor. (279 aa)
A306_00000762Rho GTPase-activating protein 18-like. (296 aa)
A306_00001420Brefeldin A-inhibited guanine nucleotide-exchange protein 1. (523 aa)
LRRC16ALeucine rich repeat containing 16A. (908 aa)
MTSS1Metastasis suppressor 1, transcript variant X1. (755 aa)
WASHC5KIAA0196 ortholog. (1193 aa)
FAM49BFamily with sequence similarity 49, member B, transcript variant X1. (324 aa)
FHOD3Formin homology 2 domain containing 3. (1519 aa)
ARHGAP28Rho GTPase activating protein 28. (675 aa)
FAM206AFamily with sequence similarity 206, member A. (150 aa)
ARFGEF1ADP-ribosylation factor guanine nucleotide-exchange factor 1 (Brefeldin A-inhibited). (1301 aa)
RHPN1Rhophilin, Rho GTPase binding protein 1. (677 aa)
CDC42EP1CDC42 effector protein (Rho GTPase binding) 1, transcript variant X1. (417 aa)
PICK1Protein interacting with PRKCA 1. (405 aa)
TMOD1Tropomodulin-1. (359 aa)
CUNH15orf62Uncharacterized protein. (176 aa)
S100A10S100 calcium binding protein A10. (58 aa)
PLEKPleckstrin, transcript variant X1. (353 aa)
A306_00013344C-C motif chemokine 3-like 1. (95 aa)
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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