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DHCR7 DHCR7 SRD5A2 SRD5A2 A306_00013448 A306_00013448 RDH8 RDH8 STARD3 STARD3 MED1 MED1 CACNA1H CACNA1H DHRS11 DHRS11 HSD17B2 HSD17B2 A306_00006782 A306_00006782 HSD17B7 HSD17B7 A306_00005787 A306_00005787 HSD17B12 HSD17B12 SRD5A1 SRD5A1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DHCR77-dehydrocholesterol reductase. (475 aa)
SRD5A23-oxo-5-alpha-steroid 4-dehydrogenase 2. (190 aa)
A306_00013448Retinol dehydrogenase 8; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (305 aa)
RDH8Retinol dehydrogenase 8 (All-trans); Belongs to the short-chain dehydrogenases/reductases (SDR) family. (277 aa)
STARD3StAR-related lipid transfer (START) domain containing 3. (441 aa)
MED1Mediator complex subunit 1. (939 aa)
CACNA1HCalcium channel, voltage-dependent, T type, alpha 1H subunit. (2387 aa)
DHRS11Dehydrogenase/reductase (SDR family) member 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (251 aa)
HSD17B2Hydroxysteroid (17-beta) dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (390 aa)
A306_00006782Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (503 aa)
HSD17B7Hydroxysteroid (17-beta) dehydrogenase 7. (306 aa)
A306_00005787Retinol dehydrogenase 8; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (316 aa)
HSD17B12Hydroxysteroid (17-beta) dehydrogenase 12, transcript variant X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (268 aa)
SRD5A13-oxo-5-alpha-steroid 4-dehydrogenase 1. (162 aa)
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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