STRINGSTRING
LLGL1 LLGL1 SEPT8 SEPT8 NSMF NSMF TMEM110 TMEM110 EPB41 EPB41 SEPT11 SEPT11 EXOC3L1 EXOC3L1 STIM1 STIM1 MYO9B MYO9B RIMS3 RIMS3 SEPT12 SEPT12 MYADM MYADM UNC13B UNC13B LASP1 LASP1 SAPCD2 SAPCD2 A306_00000228 A306_00000228 C2CD2L C2CD2L NUMA1 NUMA1 DBNL DBNL SPIRE2 SPIRE2 A306_00000068 A306_00000068 A306_00014837 A306_00014837 A306_00000103 A306_00000103 A306_00015284 A306_00015284 A306_00015009 A306_00015009 A306_00000338 A306_00000338 A306_00000178 A306_00000178 A306_00000293 A306_00000293 A306_00015115 A306_00015115 A306_00000398 A306_00000398 A306_00000182 A306_00000182 TRAF6 TRAF6 MKLN1 MKLN1 CALD1 CALD1 PXN PXN ANLN ANLN RIMS4 RIMS4 SH2D5 SH2D5 SPTAN1 SPTAN1 TMEM250 TMEM250 LANCL2 LANCL2 DMD DMD CLTA CLTA MYO9A MYO9A EXOC7 EXOC7 SEPT9 SEPT9 SEPT5 SEPT5 SPTBN1 SPTBN1 ACTR2 ACTR2 ERC2 ERC2 A306_00009072 A306_00009072 PLEKHH2 PLEKHH2 HAAO HAAO SEPT6 SEPT6 A306_00005476 A306_00005476 UNC13C UNC13C AKAP13 AKAP13 FNBP1L FNBP1L GPSM2 GPSM2 RTKN2 RTKN2 KYNU KYNU A306_00006635 A306_00006635 A306_00007057 A306_00007057 INSC INSC WASL WASL CTTNBP2 CTTNBP2 SEPT3 SEPT3 PVALB PVALB ERC1 ERC1 PHLDB2 PHLDB2 EXOC6B EXOC6B A306_00000041 A306_00000041 ACTN1 ACTN1 STXBP6 STXBP6 TNFAIP2 TNFAIP2 A306_00002277 A306_00002277 PPP1R36 PPP1R36 EXOC3L4 EXOC3L4 A306_00002940 A306_00002940 SEPT10 SEPT10 PFN4 PFN4 ARV1 ARV1 RIMS1 RIMS1 UTRN UTRN BASP1 BASP1 SPIRE1 SPIRE1 EXOC2 EXOC2 COBL COBL RIMS2 RIMS2 NIM1K NIM1K MELK MELK TDO2 TDO2 EXOC3 EXOC3 BFSP1 BFSP1 CLTB CLTB DSTN DSTN EXOC6 EXOC6 EXOC5 EXOC5 FGF1 FGF1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LLGL1Uncharacterized protein. (779 aa)
SEPT8Septin 8, transcript variant X3; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (469 aa)
NSMFNMDA receptor synaptonuclear signaling and neuronal migration factor. (532 aa)
TMEM110Transmembrane protein 110. (256 aa)
EPB41Erythrocyte membrane protein band 4.1. (509 aa)
SEPT11Septin 11, transcript variant X4; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (441 aa)
EXOC3L1Exocyst complex component 3-like 1. (753 aa)
STIM1Stromal interaction molecule 1. (711 aa)
MYO9BMyosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1833 aa)
RIMS3Regulating synaptic membrane exocytosis 3. (310 aa)
SEPT12Septin 12; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (343 aa)
MYADMMyeloid-associated differentiation marker. (299 aa)
UNC13BUncharacterized protein. (1170 aa)
LASP1LIM and SH3 protein 1. (250 aa)
SAPCD2Suppressor APC domain containing 2. (209 aa)
A306_00000228PH domain-containing protein. (507 aa)
C2CD2LC2CD2-like. (610 aa)
NUMA1Nuclear mitotic apparatus protein 1. (975 aa)
DBNLDrebrin-like. (537 aa)
SPIRE2Spire-type actin nucleation factor 2. (444 aa)
A306_00000068Uncharacterized protein. (1687 aa)
A306_00014837Alpha-actinin-4-like. (847 aa)
A306_00000103Uncharacterized protein. (409 aa)
A306_00015284Rhotekin-like. (83 aa)
A306_00015009Spectrin beta chain, non-erythrocytic 4. (933 aa)
A306_00000338Uncharacterized protein. (223 aa)
A306_00000178Uncharacterized protein. (433 aa)
A306_00000293Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (305 aa)
A306_00015115Putative LOC106146006. (442 aa)
A306_00000398Calponin-homology (CH) domain-containing protein. (115 aa)
A306_00000182Uncharacterized protein. (826 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa)
MKLN1Muskelin 1, intracellular mediator containing kelch motifs. (740 aa)
CALD1Caldesmon 1, transcript variant X1. (769 aa)
PXNPaxillin, transcript variant X1; Belongs to the paxillin family. (572 aa)
ANLNAnillin actin binding protein. (1096 aa)
RIMS4Regulating synaptic membrane exocytosis 4. (242 aa)
SH2D5SH2 domain containing 5. (246 aa)
SPTAN1Spectrin, alpha, non-erythrocytic 1, transcript variant X1. (2533 aa)
TMEM250Uncharacterized protein. (139 aa)
LANCL2LanC lantibiotic synthetase component C-like 2 (Bacterial). (370 aa)
DMDDystrophin; May play a role in anchoring the cytoskeleton to the plasma membrane. (3318 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (244 aa)
MYO9AMyosin IXA. (1495 aa)
EXOC7Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (701 aa)
SEPT9Septin 9, transcript variant X1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (592 aa)
SEPT5Septin 5, transcript variant X1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (399 aa)
SPTBN1Spectrin, beta, non-erythrocytic 1. (936 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (381 aa)
ERC2ELKS/RAB6-interacting/CAST family member 2. (342 aa)
A306_00009072ERC protein 2. (433 aa)
PLEKHH2Pleckstrin homology domain containing, family H (With MyTH4 domain) member 2. (1499 aa)
HAAO3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (286 aa)
SEPT6Septin 6, transcript variant X1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (420 aa)
A306_00005476Phorbol ester/diacylglycerol-binding protein unc-13. (198 aa)
UNC13CUncharacterized protein. (2206 aa)
AKAP13A kinase (PRKA) anchor protein 13, transcript variant X1. (2461 aa)
FNBP1LFormin binding protein 1-like. (609 aa)
GPSM2G-protein signaling modulator 2. (663 aa)
RTKN2Rhotekin 2. (584 aa)
KYNUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (474 aa)
A306_00006635Putative LOC102090370. (1123 aa)
A306_00007057Transmembrane protein 110. (230 aa)
INSCINSC_LBD domain-containing protein. (531 aa)
WASLWiskott-Aldrich syndrome-like, transcript variant X1. (456 aa)
CTTNBP2Cortactin binding protein 2. (1081 aa)
SEPT3Septin 3; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (336 aa)
PVALBParvalbumin, transcript variant X1; Belongs to the parvalbumin family. (110 aa)
ERC1ELKS/RAB6-interacting/CAST family member 1, transcript variant X4. (1117 aa)
PHLDB2Pleckstrin homology-like domain, family B, member 2. (1273 aa)
EXOC6BExocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (908 aa)
A306_00000041Sec3-PIP2_bind domain-containing protein. (160 aa)
ACTN1Actinin, alpha 1, transcript variant X6. (864 aa)
STXBP6Syntaxin binding protein 6 (Amisyn). (210 aa)
TNFAIP2Tumor necrosis factor, alpha-induced protein 2. (684 aa)
A306_00002277Putative LOC102084103. (656 aa)
PPP1R36Protein phosphatase 1, regulatory subunit 36. (426 aa)
EXOC3L4Exocyst complex component 3-like 4, transcript variant X1. (702 aa)
A306_00002940Protein spire homolog 1. (622 aa)
SEPT10Septin 10; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (490 aa)
PFN4Uncharacterized protein; Belongs to the profilin family. (108 aa)
ARV1ARV1 homolog, fatty acid homeostatsis modulator. (199 aa)
RIMS1Regulating synaptic membrane exocytosis 1. (1413 aa)
UTRNUtrophin; May play a role in anchoring the cytoskeleton to the plasma membrane. (3461 aa)
BASP1Brain abundant, membrane attached signal protein 1. (244 aa)
SPIRE1Spire-type actin nucleation factor 1. (639 aa)
EXOC2Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (925 aa)
COBLCordon-bleu WH2 repeat protein, transcript variant X1. (1363 aa)
RIMS2Regulating synaptic membrane exocytosis 2. (1116 aa)
NIM1KNIM1 serine/threonine protein kinase; Belongs to the protein kinase superfamily. (436 aa)
MELKNon-specific serine/threonine protein kinase. (657 aa)
TDO2Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (406 aa)
EXOC3Exocyst complex component 3. (745 aa)
BFSP1Beaded filament structural protein 1, filensin; Belongs to the intermediate filament family. (656 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (173 aa)
DSTNDestrin (Actin depolymerizing factor), transcript variant X1; Belongs to the actin-binding proteins ADF family. (165 aa)
EXOC6Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (732 aa)
EXOC5Exocyst complex component 5, transcript variant X1. (719 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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