STRINGSTRING
EML4 EML4 GNB4 GNB4 TBL1XR1 TBL1XR1 DAW1 DAW1 WDFY1 WDFY1 WDR78 WDR78 RFWD2 RFWD2 CDC20 CDC20 CFAP57 CFAP57 WDR72 WDR72 TLE3 TLE3 DMXL2 DMXL2 CORO2B CORO2B WDR76 WDR76 GNB5 GNB5 WDR47 WDR47 PPP2R2D PPP2R2D BUB3 BUB3 TAF5 TAF5 TLE1 TLE1 WDSUB1 WDSUB1 WDFY3 WDFY3 SEC31A SEC31A KIF21A KIF21A A306_00004006 A306_00004006 DYNC1I2 DYNC1I2 NUP37 NUP37 PWP1 PWP1 TBL1X TBL1X DCAF6 DCAF6 WDR3 WDR3 GNB3 GNB3 RBBP7 RBBP7 WDR19 WDR19 WDR1 WDR1 PPP2R2C PPP2R2C WDR17 WDR17 NWD2 NWD2 DCAF4 DCAF4 DDB2 DDB2 ZNF106 ZNF106 DCAF5 DCAF5 WDR20 WDR20 EML1 EML1 AMBRA1 AMBRA1 WDR89 WDR89 STRN3 STRN3 MAPKBP1 MAPKBP1 EML5 EML5 WDR25 WDR25 WDR37 WDR37 PIK3R4 PIK3R4 WDR48 WDR48 WDR60 WDR60 DYNC1I1 DYNC1I1 WDR86 WDR86 BRWD1 BRWD1 WDFY2 WDFY2 CHAF1B CHAF1B CFAP44 CFAP44 TULP4 TULP4 TSSC1 TSSC1 LYST LYST PEX7 PEX7 PHIP PHIP STXBP5 STXBP5 AHI1 AHI1 WDR64 WDR64 TAF5L TAF5L WDR27 WDR27 WDR35 WDR35 NUP43 NUP43 CDC40 CDC40 PAK1IP1 PAK1IP1 NSMAF NSMAF SEH1L SEH1L TBC1D31 TBC1D31 DCAF13 DCAF13 ELP2 ELP2 WDTC1 WDTC1 PRPF19 PRPF19 A306_00015172 A306_00015172 DNAI2 DNAI2 RRP9 RRP9 WDR24 WDR24 FZR1 FZR1 A306_00000188 A306_00000188 DCAF10 DCAF10 AAMP AAMP A306_00014793 A306_00014793 A306_00014728 A306_00014728 FBXW5 FBXW5 A306_00014773 A306_00014773 KIF21B KIF21B GTF3C2 GTF3C2 CIAO1 CIAO1 A306_00014261 A306_00014261 MED16 MED16 WDR18 WDR18 BOP1 BOP1 NBEAL2 NBEAL2 DCAF12 DCAF12 COPA COPA DNAI1 DNAI1 DCAF8 DCAF8 MLXIPL MLXIPL DCAF7 DCAF7 CORO6 CORO6 EIF3I EIF3I RBBP4 RBBP4 RPTOR RPTOR WDR90 WDR90 BTRC BTRC FBXW4 FBXW4 A306_00000138 A306_00000138 EDC4 EDC4 TLE2 TLE2 WDR91 WDR91 WDR55 WDR55 WDR7 WDR7 SNRNP40 SNRNP40 BRWD3 BRWD3 WDR82 WDR82 POC1A POC1A FBXW11 FBXW11 WDR31 WDR31 PRPF4 PRPF4 DPH7 DPH7 PPP2R2B PPP2R2B PPP2R2A PPP2R2A TBL3 TBL3 LLGL1 LLGL1 TRAF7 TRAF7 WDR33 WDR33 ATG16L1 ATG16L1 WDR70 WDR70 IFT122 IFT122 WDHD1 WDHD1 SEC13 SEC13 NEDD1 NEDD1 APAF1 APAF1 VPS8 VPS8 WDR53 WDR53 COPB2 COPB2 GEMIN5 GEMIN5 POC1B POC1B THOC3 THOC3 IFT140 IFT140 MLST8 MLST8 UTP15 UTP15 NBEAL1 NBEAL1 WDR12 WDR12 PLRG1 PLRG1 FBXW7 FBXW7 STRAP STRAP SEC31B SEC31B STRN STRN WSB1 WSB1 PAFAH1B1 PAFAH1B1 NLE1 NLE1 WSB2 WSB2 FBXW8 FBXW8 RBBP5 RBBP5 WDR77 WDR77 WDR59 WDR59 ARPC1A ARPC1A ARPC1B ARPC1B EED EED PPWD1 PPWD1 WDR41 WDR41 IFT80 IFT80 LRWD1 LRWD1 WDR81 WDR81 PAAF1 PAAF1 GNB1 GNB1 WDR5 WDR5 FBXW2 FBXW2 WDR34 WDR34 WDR44 WDR44 WDR26 WDR26 ERCC8 ERCC8 CDC20B CDC20B SMU1 SMU1 PLAA PLAA CORO2A CORO2A WDR4 WDR4 PWP2 PWP2 CSTF1 CSTF1 RAE1 RAE1 HERC1 HERC1 WDR61 WDR61 UTP18 UTP18 LLGL2 LLGL2 KATNB1 KATNB1 GNB1L GNB1L A306_00005274 A306_00005274 WDR66 WDR66 CORO1C CORO1C DMXL1 DMXL1 WDR36 WDR36 EML6 EML6 WDR92 WDR92 DTL DTL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EML4Echinoderm microtubule associated protein like 4, transcript variant X1. (907 aa)
GNB4Guanine nucleotide binding protein (G protein), beta polypeptide 4. (340 aa)
TBL1XR1Transducin (Beta)-like 1 X-linked receptor 1, transcript variant X1. (513 aa)
DAW1Dynein assembly factor with WDR repeat domains 1. (463 aa)
WDFY1WD repeat and FYVE domain containing 1. (462 aa)
WDR78WD repeat domain 78. (704 aa)
RFWD2Ring finger and WD repeat domain 2, E3 ubiquitin protein ligase, transcript variant X2. (590 aa)
CDC20Cell division cycle 20. (474 aa)
CFAP57Cilia and flagella associated protein 57. (1080 aa)
WDR72WD repeat domain 72. (999 aa)
TLE3Transducin-like enhancer of split 3. (678 aa)
DMXL2Dmx-like 2, transcript variant X2. (3034 aa)
CORO2BCoronin; Belongs to the WD repeat coronin family. (488 aa)
WDR76WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (466 aa)
GNB5Guanine nucleotide binding protein (G protein), beta 5. (388 aa)
WDR47WD repeat domain 47, transcript variant X3. (920 aa)
PPP2R2DSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (295 aa)
BUB3BUB3 mitotic checkpoint protein, transcript variant X1. (329 aa)
TAF5TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa. (634 aa)
TLE1Uncharacterized protein. (467 aa)
WDSUB1WD repeat, sterile alpha motif and U-box domain containing 1, transcript variant X1. (478 aa)
WDFY3WD repeat and FYVE domain containing 3, transcript variant X1. (3512 aa)
SEC31ASEC31 homolog A, COPII coat complex component, transcript variant X1. (1280 aa)
KIF21AKinesin family member 21A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1444 aa)
A306_00004006WD repeat-containing protein 75-like. (504 aa)
DYNC1I2Dynein, cytoplasmic 1, intermediate chain 2, transcript variant X3. (629 aa)
NUP37Nucleoporin 37kDa. (326 aa)
PWP1PWP1 homolog, endonuclein. (499 aa)
TBL1XTransducin (Beta)-like 1X-linked, transcript variant X1. (516 aa)
DCAF6DDB1 and CUL4 associated factor 6. (930 aa)
WDR3WD repeat domain 3. (938 aa)
GNB3Guanine nucleotide binding protein (G protein), beta polypeptide 3. (340 aa)
RBBP7Retinoblastoma binding protein 7. (422 aa)
WDR19WD repeat domain 19. (1344 aa)
WDR1WD repeat domain 1. (620 aa)
PPP2R2CSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (428 aa)
WDR17WD repeat domain 17, transcript variant X2. (1283 aa)
NWD2NACHT and WD repeat domain containing 2. (1767 aa)
DCAF4DDB1 and CUL4 associated factor 4. (500 aa)
DDB2Damage-specific DNA binding protein 2, 48kDa. (508 aa)
ZNF106Zinc finger protein 106, transcript variant X1. (1872 aa)
DCAF5DDB1 and CUL4 associated factor 5, transcript variant X2. (725 aa)
WDR20WD repeat domain 20. (532 aa)
EML1Echinoderm microtubule associated protein like 1, transcript variant X1. (832 aa)
AMBRA1Autophagy/beclin-1 regulator 1. (656 aa)
WDR89WD repeat domain 89, transcript variant X1. (410 aa)
STRN3Striatin, calmodulin binding protein 3, transcript variant X1. (681 aa)
MAPKBP1Mitogen-activated protein kinase binding protein 1. (1680 aa)
EML5Echinoderm microtubule associated protein like 5. (1935 aa)
WDR25WD repeat domain 25. (509 aa)
WDR37WD repeat domain 37. (495 aa)
PIK3R4Phosphoinositide-3-kinase, regulatory subunit 4, transcript variant X1. (1361 aa)
WDR48WD repeat domain 48. (662 aa)
WDR60WD repeat domain 60. (1189 aa)
DYNC1I1Dynein, cytoplasmic 1, intermediate chain 1. (611 aa)
WDR86WD repeat domain 86. (398 aa)
BRWD1Bromodomain and WD repeat domain containing 1. (2292 aa)
WDFY2WD repeat and FYVE domain containing 2. (372 aa)
CHAF1BChromatin assembly factor 1, subunit B (p60). (573 aa)
CFAP44Cilia and flagella associated protein 44. (1802 aa)
TULP4Tubby like protein 4. (735 aa)
TSSC1Tumor suppressing subtransferable candidate 1. (407 aa)
LYSTLysosomal trafficking regulator. (3804 aa)
PEX7WD_REPEATS_REGION domain-containing protein. (243 aa)
PHIPPleckstrin homology domain interacting protein. (1727 aa)
STXBP5Syntaxin binding protein 5 (Tomosyn). (1267 aa)
AHI1Abelson helper integration site 1. (1254 aa)
WDR64WD repeat domain 64. (1045 aa)
TAF5LTAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa. (634 aa)
WDR27WD repeat domain 27. (813 aa)
WDR35WD repeat-containing protein 35. (1167 aa)
NUP43Nucleoporin 43kDa. (297 aa)
CDC40Cell division cycle 40. (540 aa)
PAK1IP1PAK1 interacting protein 1. (381 aa)
NSMAFNeutral sphingomyelinase (N-SMase) activation associated factor. (901 aa)
SEH1LSEH1-like nucleoporin; Belongs to the WD repeat SEC13 family. (325 aa)
TBC1D31TBC1 domain family, member 31. (1104 aa)
DCAF13DDB1 and CUL4 associated factor 13. (464 aa)
ELP2Elongator acetyltransferase complex subunit 2. (822 aa)
WDTC1WD and tetratricopeptide repeats protein 1. (671 aa)
PRPF19Uncharacterized protein. (336 aa)
A306_00015172F-box/WD repeat-containing protein 7. (357 aa)
DNAI2Dynein, axonemal, intermediate chain 2. (603 aa)
RRP9WD_REPEATS_REGION domain-containing protein. (464 aa)
WDR24WD repeat domain 24. (789 aa)
FZR1Fizzy/cell division cycle 20 related 1. (493 aa)
A306_00000188Coronin; Belongs to the WD repeat coronin family. (475 aa)
DCAF10DDB1 and CUL4 associated factor 10. (376 aa)
AAMPAngio-associated, migratory cell protein. (402 aa)
A306_00014793Guanine nucleotide-binding protein subunit beta-2-like 1. (329 aa)
A306_00014728F-box/WD repeat-containing protein 10. (839 aa)
FBXW5F-box and WD repeat domain containing 5. (546 aa)
A306_00014773WD repeat-containing protein 62. (961 aa)
KIF21BKinesin family member 21B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1530 aa)
GTF3C2General transcription factor IIIC, polypeptide 2, beta 110kDa. (766 aa)
CIAO1Cytosolic iron-sulfur assembly component 1. (215 aa)
A306_00014261Transducin-like enhancer protein 1. (641 aa)
MED16Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (831 aa)
WDR18WD repeat domain 18. (664 aa)
BOP1Block of proliferation 1. (480 aa)
NBEAL2Uncharacterized protein. (661 aa)
DCAF12DDB1 and CUL4 associated factor 12. (460 aa)
COPACoatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1224 aa)
DNAI1Dynein, axonemal, intermediate chain 1. (680 aa)
DCAF8DDB1 and CUL4 associated factor 8. (309 aa)
MLXIPLMLX interacting protein-like. (731 aa)
DCAF7DDB1 and CUL4 associated factor 7. (321 aa)
CORO6Coronin 6. (437 aa)
EIF3IEukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (307 aa)
RBBP4Retinoblastoma binding protein 4. (393 aa)
RPTORRegulatory associated protein of MTOR, complex 1. (1345 aa)
WDR90WD repeat domain 90. (2928 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase, transcript variant X1. (633 aa)
FBXW4F-box and WD repeat domain containing 4. (291 aa)
A306_00000138Uncharacterized protein. (1075 aa)
EDC4Enhancer of mRNA decapping 4. (1385 aa)
TLE2Transducin-like enhancer of split 2. (338 aa)
WDR91WD repeat domain 91. (781 aa)
WDR55WD repeat domain 55. (306 aa)
WDR7WD repeat domain 7. (855 aa)
SNRNP40Small nuclear ribonucleoprotein 40kDa (U5). (348 aa)
BRWD3Bromodomain and WD repeat domain containing 3. (1379 aa)
WDR82WD repeat domain 82. (313 aa)
POC1APOC1 centriolar protein A. (368 aa)
FBXW11F-box and WD repeat domain containing 11, transcript variant X3. (531 aa)
WDR31WD repeat domain 31. (340 aa)
PRPF4Pre-mRNA processing factor 4. (572 aa)
DPH7Diphthamide biosynthesis 7. (484 aa)
PPP2R2BSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (290 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (450 aa)
TBL3Transducin (Beta)-like 3. (881 aa)
LLGL1Uncharacterized protein. (779 aa)
TRAF7TNF receptor-associated factor 7, E3 ubiquitin protein ligase. (670 aa)
WDR33WD repeat domain 33, transcript variant X1. (1314 aa)
ATG16L1Autophagy related 16-like 1, transcript variant X1. (562 aa)
WDR70WD repeat domain 70. (440 aa)
IFT122Intraflagellar transport 122. (1167 aa)
WDHD1WD repeat and HMG-box DNA binding protein 1, transcript variant X1. (1124 aa)
SEC13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (306 aa)
NEDD1Neural cell expressed, developmentally down-regulated 1. (776 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa)
VPS8WD_REPEATS_REGION domain-containing protein. (1376 aa)
WDR53WD repeat domain 53. (354 aa)
COPB2Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (884 aa)
GEMIN5Gem (Nuclear organelle) associated protein 5. (865 aa)
POC1BPOC1 centriolar protein B. (426 aa)
THOC3THO complex 3. (269 aa)
IFT140Intraflagellar transport 140. (1454 aa)
MLST8MTOR associated protein, LST8 homolog. (271 aa)
UTP15WD_REPEATS_REGION domain-containing protein. (529 aa)
NBEAL1Neurobeachin-like 1. (1351 aa)
WDR12WD repeat domain 12. (290 aa)
PLRG1Pleiotropic regulator 1. (513 aa)
FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase. (487 aa)
STRAPSerine/threonine kinase receptor associated protein. (309 aa)
SEC31BSEC31 homolog B, COPII coat complex component. (471 aa)
STRNStriatin, calmodulin binding protein, transcript variant X2. (705 aa)
WSB1WD repeat and SOCS box containing 1. (422 aa)
PAFAH1B1Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family. (410 aa)
NLE1WD_REPEATS_REGION domain-containing protein. (478 aa)
WSB2WD repeat and SOCS box containing 2. (350 aa)
FBXW8F-box and WD repeat domain containing 8. (520 aa)
RBBP5Retinoblastoma binding protein 5. (527 aa)
WDR77WD repeat domain 77. (297 aa)
WDR59WD repeat domain 59. (1003 aa)
ARPC1AActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (370 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (369 aa)
EEDEmbryonic ectoderm development. (441 aa)
PPWD1Peptidylprolyl isomerase domain and WD repeat containing 1, transcript variant X1. (622 aa)
WDR41WD repeat domain 41. (459 aa)
IFT80Intraflagellar transport 80. (741 aa)
LRWD1Leucine-rich repeats and WD repeat domain containing 1. (746 aa)
WDR81WD repeat domain 81. (1884 aa)
PAAF1Proteasomal ATPase-associated factor 1, transcript variant X1. (392 aa)
GNB1Guanine nucleotide binding protein (G protein), beta polypeptide 1. (340 aa)
WDR5WD repeat domain 5. (334 aa)
FBXW2F-box and WD repeat domain containing 2, transcript variant X1. (454 aa)
WDR34WD repeat domain 34. (544 aa)
WDR44WD repeat domain 44, transcript variant X1. (923 aa)
WDR26WD repeat domain 26, transcript variant X1. (517 aa)
ERCC8Excision repair cross-complementation group 8, transcript variant X1. (341 aa)
CDC20BCell division cycle 20B. (492 aa)
SMU1Uncharacterized protein. (499 aa)
PLAAPhospholipase A2-activating protein, transcript variant X1. (749 aa)
CORO2ACoronin; Belongs to the WD repeat coronin family. (453 aa)
WDR4tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. (404 aa)
PWP2WD_REPEATS_REGION domain-containing protein. (951 aa)
CSTF1Cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa. (465 aa)
RAE1Ribonucleic acid export 1, transcript variant X1. (413 aa)
HERC1HECT and RLD domain containing E3 ubiquitin protein ligase family member 1. (3373 aa)
WDR61WD repeat domain 61. (305 aa)
UTP18Uncharacterized protein. (481 aa)
LLGL2WD_REPEATS_REGION domain-containing protein. (1026 aa)
KATNB1Katanin p80 (WD repeat containing) subunit B 1. (655 aa)
GNB1LGuanine nucleotide binding protein (G protein), beta polypeptide 1-like. (341 aa)
A306_00005274Protein HIRA; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (978 aa)
WDR66WD repeat domain 66. (1002 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (474 aa)
DMXL1Dmx-like 1, transcript variant X2. (3057 aa)
WDR36WD repeat domain 36. (886 aa)
EML6Echinoderm microtubule associated protein like 6. (1373 aa)
WDR92WD repeat domain 92. (309 aa)
DTLWD_REPEATS_REGION domain-containing protein. (685 aa)
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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