37 items (Columba livia) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MEMO1	Mediator of cell motility 1. (201 aa)
	HRAS	Uncharacterized protein. (189 aa)
	ERBB4	Receptor protein-tyrosine kinase. (1323 aa)
	KRAS	Uncharacterized protein. (197 aa)
	FNDC3A	Fibronectin type III domain containing 3A, transcript variant X1. (1199 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	YES1	Tyrosine-protein kinase. (541 aa)
	EREG	Epiregulin. (118 aa)
	NRG3	Neuregulin 3. (377 aa)
	USP8	Ubiquitin specific peptidase 8, transcript variant X3; Belongs to the peptidase C19 family. (1121 aa)
	CUL5	Cullin 5; Belongs to the cullin family. (759 aa)
	FNDC3B	Uncharacterized protein. (1154 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1052 aa)
	HBEGF	Heparin-binding EGF-like growth factor. (158 aa)
	NRG2	Neuregulin 2. (466 aa)
	RPS27A	Ribosomal protein S27a. (156 aa)
	EGF	Epidermal growth factor. (1254 aa)
	GRB2	Growth factor receptor-bound protein 2. (250 aa)
	PRKCA	Protein kinase C, alpha; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (615 aa)
	NRG4	Neuregulin 4, transcript variant X1. (116 aa)
	NRG1	Neuregulin 1, transcript variant X1. (685 aa)
	EGFR	Receptor protein-tyrosine kinase. (1164 aa)
	SRC	SRC proto-oncogene, non-receptor tyrosine kinase. (320 aa)
	NRAS	Neuroblastoma RAS viral (V-ras) oncogene homolog. (123 aa)
	CSDE1	Cold shock domain containing E1, RNA-binding. (796 aa)
	SOS1	Uncharacterized protein. (1323 aa)
	PRKCD	Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (685 aa)
	A306_00011441	Fibronectin type-III domain-containing protein 3a-like, transcript variant X1. (1189 aa)
	BTC	Betacellulin. (213 aa)
	SHC1	SHC (Src homology 2 domain containing) transforming protein 1. (345 aa)
	ERBB2	Receptor protein-tyrosine kinase. (929 aa)
	RNF41	Ring finger protein 41, E3 ubiquitin protein ligase. (317 aa)
	PRKCQ	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (732 aa)
	A306_00014151	Receptor tyrosine-protein kinase erbB-3. (580 aa)
	MATK	Tyrosine-protein kinase. (447 aa)
	STUB1	U-box domain-containing protein. (93 aa)
	GAB1	GRB2-associated binding protein 1. (718 aa)

Your Current Organism:

Columba livia

NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A306_00014151	BTC	A0A2I0LK79	A0A2I0LMD4	Receptor tyrosine-protein kinase erbB-3.	Betacellulin.	0.505
A306_00014151	CSDE1	A0A2I0LK79	A0A2I0LZZ5	Receptor tyrosine-protein kinase erbB-3.	Cold shock domain containing E1, RNA-binding.	0.490
A306_00014151	CUL5	A0A2I0LK79	A0A2I0MCY1	Receptor tyrosine-protein kinase erbB-3.	Cullin 5; Belongs to the cullin family.	0.437
A306_00014151	EGF	A0A2I0LK79	A0A2I0M930	Receptor tyrosine-protein kinase erbB-3.	Epidermal growth factor.	0.832
A306_00014151	EREG	A0A2I0LK79	A0A2I0MGS1	Receptor tyrosine-protein kinase erbB-3.	Epiregulin.	0.606
A306_00014151	GAB1	A0A2I0LK79	A0A2I0MH30	Receptor tyrosine-protein kinase erbB-3.	GRB2-associated binding protein 1.	0.686
A306_00014151	GRB2	A0A2I0LK79	A0A2I0M7L1	Receptor tyrosine-protein kinase erbB-3.	Growth factor receptor-bound protein 2.	0.879
A306_00014151	HBEGF	A0A2I0LK79	A0A2I0MAA3	Receptor tyrosine-protein kinase erbB-3.	Heparin-binding EGF-like growth factor.	0.695
A306_00014151	HRAS	A0A2I0LK79	A0A2I0MI00	Receptor tyrosine-protein kinase erbB-3.	Uncharacterized protein.	0.490
A306_00014151	KRAS	A0A2I0LK79	A0A2I0MKD5	Receptor tyrosine-protein kinase erbB-3.	Uncharacterized protein.	0.490
A306_00014151	MATK	A0A2I0LK79	A0A2I0LJK6	Receptor tyrosine-protein kinase erbB-3.	Tyrosine-protein kinase.	0.499
A306_00014151	MEMO1	A0A2I0LK79	A0A2I0LKS7	Receptor tyrosine-protein kinase erbB-3.	Mediator of cell motility 1.	0.560
A306_00014151	NRAS	A0A2I0LK79	A0A2I0LZZ9	Receptor tyrosine-protein kinase erbB-3.	Neuroblastoma RAS viral (V-ras) oncogene homolog.	0.490
A306_00014151	NRG1	A0A2I0LK79	A0A2I0M6D3	Receptor tyrosine-protein kinase erbB-3.	Neuregulin 1, transcript variant X1.	0.744
A306_00014151	NRG2	A0A2I0LK79	A0A2I0MA98	Receptor tyrosine-protein kinase erbB-3.	Neuregulin 2.	0.744
A306_00014151	PIK3CA	A0A2I0LK79	A0A2I0MBJ9	Receptor tyrosine-protein kinase erbB-3.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.543
A306_00014151	RNF41	A0A2I0LK79	A0A2I0LK86	Receptor tyrosine-protein kinase erbB-3.	Ring finger protein 41, E3 ubiquitin protein ligase.	0.688
A306_00014151	RPS27A	A0A2I0LK79	A0A2I0M9A1	Receptor tyrosine-protein kinase erbB-3.	Ribosomal protein S27a.	0.459
A306_00014151	SHC1	A0A2I0LK79	A0A2I0LM13	Receptor tyrosine-protein kinase erbB-3.	SHC (Src homology 2 domain containing) transforming protein 1.	0.749
A306_00014151	SOS1	A0A2I0LK79	A0A2I0LT24	Receptor tyrosine-protein kinase erbB-3.	Uncharacterized protein.	0.696