14 items (Columba livia) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	KRAS	Uncharacterized protein. (197 aa)
	SHC1	SHC (Src homology 2 domain containing) transforming protein 1. (345 aa)
	BTC	Betacellulin. (213 aa)
	SOS1	Uncharacterized protein. (1323 aa)
	CSDE1	Cold shock domain containing E1, RNA-binding. (796 aa)
	NRAS	Neuroblastoma RAS viral (V-ras) oncogene homolog. (123 aa)
	NRG1	Neuregulin 1, transcript variant X1. (685 aa)
	NRG4	Neuregulin 4, transcript variant X1. (116 aa)
	GRB2	Growth factor receptor-bound protein 2. (250 aa)
	NRG2	Neuregulin 2. (466 aa)
	HBEGF	Heparin-binding EGF-like growth factor. (158 aa)
	NRG3	Neuregulin 3. (377 aa)
	EREG	Epiregulin. (118 aa)
	HRAS	Uncharacterized protein. (189 aa)

Your Current Organism:

Columba livia

NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BTC	EREG	A0A2I0LMD4	A0A2I0MGS1	Betacellulin.	Epiregulin.	0.776
BTC	GRB2	A0A2I0LMD4	A0A2I0M7L1	Betacellulin.	Growth factor receptor-bound protein 2.	0.518
BTC	HBEGF	A0A2I0LMD4	A0A2I0MAA3	Betacellulin.	Heparin-binding EGF-like growth factor.	0.754
BTC	NRG1	A0A2I0LMD4	A0A2I0M6D3	Betacellulin.	Neuregulin 1, transcript variant X1.	0.504
BTC	NRG2	A0A2I0LMD4	A0A2I0MA98	Betacellulin.	Neuregulin 2.	0.504
CSDE1	GRB2	A0A2I0LZZ5	A0A2I0M7L1	Cold shock domain containing E1, RNA-binding.	Growth factor receptor-bound protein 2.	0.623
CSDE1	SOS1	A0A2I0LZZ5	A0A2I0LT24	Cold shock domain containing E1, RNA-binding.	Uncharacterized protein.	0.676
EREG	BTC	A0A2I0MGS1	A0A2I0LMD4	Epiregulin.	Betacellulin.	0.776
EREG	GRB2	A0A2I0MGS1	A0A2I0M7L1	Epiregulin.	Growth factor receptor-bound protein 2.	0.445
EREG	HBEGF	A0A2I0MGS1	A0A2I0MAA3	Epiregulin.	Heparin-binding EGF-like growth factor.	0.722
EREG	NRG1	A0A2I0MGS1	A0A2I0M6D3	Epiregulin.	Neuregulin 1, transcript variant X1.	0.422
EREG	NRG2	A0A2I0MGS1	A0A2I0MA98	Epiregulin.	Neuregulin 2.	0.422
EREG	SOS1	A0A2I0MGS1	A0A2I0LT24	Epiregulin.	Uncharacterized protein.	0.405
GRB2	BTC	A0A2I0M7L1	A0A2I0LMD4	Growth factor receptor-bound protein 2.	Betacellulin.	0.518
GRB2	CSDE1	A0A2I0M7L1	A0A2I0LZZ5	Growth factor receptor-bound protein 2.	Cold shock domain containing E1, RNA-binding.	0.623
GRB2	EREG	A0A2I0M7L1	A0A2I0MGS1	Growth factor receptor-bound protein 2.	Epiregulin.	0.445
GRB2	HBEGF	A0A2I0M7L1	A0A2I0MAA3	Growth factor receptor-bound protein 2.	Heparin-binding EGF-like growth factor.	0.503
GRB2	HRAS	A0A2I0M7L1	A0A2I0MI00	Growth factor receptor-bound protein 2.	Uncharacterized protein.	0.623
GRB2	KRAS	A0A2I0M7L1	A0A2I0MKD5	Growth factor receptor-bound protein 2.	Uncharacterized protein.	0.623
GRB2	NRAS	A0A2I0M7L1	A0A2I0LZZ9	Growth factor receptor-bound protein 2.	Neuroblastoma RAS viral (V-ras) oncogene homolog.	0.623