21 items (Columba livia) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A306_00005714	Coagulation factor XIII B chain. (1158 aa)
	SERPINC1	Serpin peptidase inhibitor, clade C (Antithrombin), member 1; Belongs to the serpin family. (502 aa)
	PROS1	Protein S (Alpha). (619 aa)
	F2	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (609 aa)
	A306_00002227	Serine protease inhibitor 2.1; Belongs to the serpin family. (419 aa)
	A306_00002225	Alpha-1-antitrypsin; Belongs to the serpin family. (429 aa)
	A306_00002226	Alpha-1-antitrypsin; Belongs to the serpin family. (421 aa)
	A306_00002224	Alpha-1-antiproteinase 2, transcript variant X1; Belongs to the serpin family. (420 aa)
	SERPIND1	Serpin peptidase inhibitor, clade D (Heparin cofactor), member 1; Belongs to the serpin family. (304 aa)
	F10	Coagulation factor X; Belongs to the peptidase S1 family. (462 aa)
	F5	Coagulation factor V (Proaccelerin, labile factor); Belongs to the multicopper oxidase family. (1931 aa)
	F13A1	Coagulation factor XIII, A1 polypeptide. (595 aa)
	PROC	Protein C (Inactivator of coagulation factors Va and VIIIa), transcript variant X1. (433 aa)
	PROCR	Protein C receptor, endothelial. (223 aa)
	FGA	Fibrinogen alpha chain. (766 aa)
	FGB	Fibrinogen beta chain. (480 aa)
	FGG	Fibrinogen gamma chain. (436 aa)
	SERPINE2	Glia-derived nexin isoform X2; Belongs to the serpin family. (436 aa)
	THBD	Thrombomodulin. (204 aa)
	F8	Coagulation factor VIII, procoagulant component, transcript variant X1; Belongs to the multicopper oxidase family. (2231 aa)
	F2R	Coagulation factor II (Thrombin) receptor; Belongs to the G-protein coupled receptor 1 family. (453 aa)

Your Current Organism:

Columba livia

NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A306_00002224	F2	A0A2I0MP25	A0A2I0MNE5	Alpha-1-antiproteinase 2, transcript variant X1; Belongs to the serpin family.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.587
A306_00002224	FGB	A0A2I0MP25	A0A2I0LXU9	Alpha-1-antiproteinase 2, transcript variant X1; Belongs to the serpin family.	Fibrinogen beta chain.	0.400
A306_00002224	PROC	A0A2I0MP25	A0A2I0LTQ6	Alpha-1-antiproteinase 2, transcript variant X1; Belongs to the serpin family.	Protein C (Inactivator of coagulation factors Va and VIIIa), transcript variant X1.	0.490
A306_00002224	SERPINC1	A0A2I0MP25	A0A2I0MED6	Alpha-1-antiproteinase 2, transcript variant X1; Belongs to the serpin family.	Serpin peptidase inhibitor, clade C (Antithrombin), member 1; Belongs to the serpin family.	0.478
A306_00002224	SERPIND1	A0A2I0MP25	A0A2I0M850	Alpha-1-antiproteinase 2, transcript variant X1; Belongs to the serpin family.	Serpin peptidase inhibitor, clade D (Heparin cofactor), member 1; Belongs to the serpin family.	0.420
A306_00002225	A306_00005714	A0A2I0MP16	A0A2I0MDQ0	Alpha-1-antitrypsin; Belongs to the serpin family.	Coagulation factor XIII B chain.	0.402
A306_00002225	F2	A0A2I0MP16	A0A2I0MNE5	Alpha-1-antitrypsin; Belongs to the serpin family.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.587
A306_00002225	FGA	A0A2I0MP16	A0A2I0LXU7	Alpha-1-antitrypsin; Belongs to the serpin family.	Fibrinogen alpha chain.	0.406
A306_00002225	FGB	A0A2I0MP16	A0A2I0LXU9	Alpha-1-antitrypsin; Belongs to the serpin family.	Fibrinogen beta chain.	0.400
A306_00002225	PROC	A0A2I0MP16	A0A2I0LTQ6	Alpha-1-antitrypsin; Belongs to the serpin family.	Protein C (Inactivator of coagulation factors Va and VIIIa), transcript variant X1.	0.514
A306_00002225	SERPINC1	A0A2I0MP16	A0A2I0MED6	Alpha-1-antitrypsin; Belongs to the serpin family.	Serpin peptidase inhibitor, clade C (Antithrombin), member 1; Belongs to the serpin family.	0.484
A306_00002225	SERPIND1	A0A2I0MP16	A0A2I0M850	Alpha-1-antitrypsin; Belongs to the serpin family.	Serpin peptidase inhibitor, clade D (Heparin cofactor), member 1; Belongs to the serpin family.	0.428
A306_00002226	F2	A0A2I0MP17	A0A2I0MNE5	Alpha-1-antitrypsin; Belongs to the serpin family.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.587
A306_00002226	FGB	A0A2I0MP17	A0A2I0LXU9	Alpha-1-antitrypsin; Belongs to the serpin family.	Fibrinogen beta chain.	0.400
A306_00002226	PROC	A0A2I0MP17	A0A2I0LTQ6	Alpha-1-antitrypsin; Belongs to the serpin family.	Protein C (Inactivator of coagulation factors Va and VIIIa), transcript variant X1.	0.490
A306_00002226	SERPINC1	A0A2I0MP17	A0A2I0MED6	Alpha-1-antitrypsin; Belongs to the serpin family.	Serpin peptidase inhibitor, clade C (Antithrombin), member 1; Belongs to the serpin family.	0.478
A306_00002226	SERPIND1	A0A2I0MP17	A0A2I0M850	Alpha-1-antitrypsin; Belongs to the serpin family.	Serpin peptidase inhibitor, clade D (Heparin cofactor), member 1; Belongs to the serpin family.	0.414
A306_00002227	A306_00005714	A0A2I0MP09	A0A2I0MDQ0	Serine protease inhibitor 2.1; Belongs to the serpin family.	Coagulation factor XIII B chain.	0.401
A306_00002227	F2	A0A2I0MP09	A0A2I0MNE5	Serine protease inhibitor 2.1; Belongs to the serpin family.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.587
A306_00002227	FGB	A0A2I0MP09	A0A2I0LXU9	Serine protease inhibitor 2.1; Belongs to the serpin family.	Fibrinogen beta chain.	0.400