38 items (Columba livia) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GRB2	Growth factor receptor-bound protein 2. (250 aa)
	PRKCA	Protein kinase C, alpha; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (615 aa)
	A306_00006107	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	GAB2	GRB2-associated binding protein 2. (643 aa)
	MMP9	Matrix metallopeptidase 9. (734 aa)
	SRC	SRC proto-oncogene, non-receptor tyrosine kinase. (320 aa)
	PIK3R1	Phosphoinositide-3-kinase, regulatory subunit 1 (Alpha), transcript variant X1. (724 aa)
	NRAS	Neuroblastoma RAS viral (V-ras) oncogene homolog. (123 aa)
	CSDE1	Cold shock domain containing E1, RNA-binding. (796 aa)
	PIK3R3	Phosphoinositide-3-kinase, regulatory subunit 3 (Gamma), transcript variant X1. (731 aa)
	KITLG	KIT ligand. (234 aa)
	CBL	Cbl proto-oncogene, E3 ubiquitin protein ligase. (909 aa)
	GRAP	GRB2-related adaptor protein, transcript variant X1. (217 aa)
	SOS1	Uncharacterized protein. (1323 aa)
	CHEK1	Checkpoint kinase 1. (310 aa)
	A306_00011441	Fibronectin type-III domain-containing protein 3a-like, transcript variant X1. (1189 aa)
	PTPRU	Protein tyrosine phosphatase, receptor type, U. (764 aa)
	PIK3R2	Phosphoinositide-3-kinase, regulatory subunit 2 (Beta). (727 aa)
	A306_00011520	Granzyme E. (237 aa)
	STAT3	Signal transducer and activator of transcription. (771 aa)
	A306_00014977	Signal transducer and activator of transcription 5B. (703 aa)
	YES1	Tyrosine-protein kinase. (541 aa)
	GRB10	Growth factor receptor-bound protein 10. (590 aa)
	LYN	Tyrosine-protein kinase. (513 aa)
	A306_00002936	Apovitellenin-1; Protein component of the very low density lipoprotein (VLDL) of egg-laying females. Potent lipoprotein lipase inhibitor, preventing the loss of triglycerides from VLDL on their way from the liver to the growing oocytes. (106 aa)
	FNDC3A	Fibronectin type III domain containing 3A, transcript variant X1. (1199 aa)
	TEC	Tyrosine-protein kinase. (633 aa)
	KIT	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (963 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (608 aa)
	KRAS	Uncharacterized protein. (197 aa)
	GRAP2	GRB2-related adaptor protein 2, transcript variant X1. (296 aa)
	GRB14	Growth factor receptor-bound protein 14. (630 aa)
	HRAS	Uncharacterized protein. (189 aa)
	FNDC3B	Uncharacterized protein. (1154 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1052 aa)
	FER	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
	PTPN11	Protein tyrosine phosphatase, non-receptor type 11. (587 aa)
	SH2B3	SH2B adaptor protein 3. (484 aa)

Your Current Organism:

Columba livia

NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A306_00006107	CBL	A0A2I0M3D4	A0A2I0LVE4	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Cbl proto-oncogene, E3 ubiquitin protein ligase.	0.545
A306_00006107	CSDE1	A0A2I0M3D4	A0A2I0LZZ5	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Cold shock domain containing E1, RNA-binding.	0.430
A306_00006107	GAB2	A0A2I0M3D4	A0A2I0M2P4	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	GRB2-associated binding protein 2.	0.641
A306_00006107	GRAP	A0A2I0M3D4	A0A2I0LTI7	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	GRB2-related adaptor protein, transcript variant X1.	0.653
A306_00006107	GRAP2	A0A2I0M3D4	A0A2I0MJS2	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	GRB2-related adaptor protein 2, transcript variant X1.	0.690
A306_00006107	GRB2	A0A2I0M3D4	A0A2I0M7L1	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Growth factor receptor-bound protein 2.	0.957
A306_00006107	HRAS	A0A2I0M3D4	A0A2I0MI00	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Uncharacterized protein.	0.430
A306_00006107	KIT	A0A2I0M3D4	A0A2I0MMR1	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.660
A306_00006107	KITLG	A0A2I0M3D4	A0A2I0LWE1	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	KIT ligand.	0.526
A306_00006107	KRAS	A0A2I0M3D4	A0A2I0MKD5	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Uncharacterized protein.	0.430
A306_00006107	LYN	A0A2I0M3D4	A0A2I0MVY9	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Tyrosine-protein kinase.	0.579
A306_00006107	NRAS	A0A2I0M3D4	A0A2I0LZZ9	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Neuroblastoma RAS viral (V-ras) oncogene homolog.	0.430
A306_00006107	PIK3CA	A0A2I0M3D4	A0A2I0MBJ9	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.652
A306_00006107	PIK3R1	A0A2I0M3D4	A0A2I0M199	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Phosphoinositide-3-kinase, regulatory subunit 1 (Alpha), transcript variant X1.	0.535
A306_00006107	PIK3R2	A0A2I0M3D4	A0A2I0LQ03	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Phosphoinositide-3-kinase, regulatory subunit 2 (Beta).	0.535
A306_00006107	PIK3R3	A0A2I0M3D4	A0A2I0LYZ1	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Phosphoinositide-3-kinase, regulatory subunit 3 (Gamma), transcript variant X1.	0.535
A306_00006107	PTPN11	A0A2I0M3D4	A0A2I0M8A8	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Protein tyrosine phosphatase, non-receptor type 11.	0.901
A306_00006107	PTPN6	A0A2I0M3D4	A0A2I0ML98	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.485
A306_00006107	SOS1	A0A2I0M3D4	A0A2I0LT24	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Uncharacterized protein.	0.937
A306_00006107	SRC	A0A2I0M3D4	A0A2I0M2A8	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	SRC proto-oncogene, non-receptor tyrosine kinase.	0.629