32 items (Columba livia) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Predicted Interactions

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Your Input:
	PDGFB	Platelet-derived growth factor beta polypeptide; Belongs to the PDGF/VEGF growth factor family. (256 aa)
	HRAS	Uncharacterized protein. (189 aa)
	FNDC3B	Uncharacterized protein. (1154 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1052 aa)
	PDGFRB	Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1137 aa)
	PTPN11	Protein tyrosine phosphatase, non-receptor type 11. (587 aa)
	GRB2	Growth factor receptor-bound protein 2. (250 aa)
	CASS4	Cas scaffolding protein family member 4. (831 aa)
	RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1. (1032 aa)
	A306_00006107	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	SRC	SRC proto-oncogene, non-receptor tyrosine kinase. (320 aa)
	PLCG1	Phosphoinositide phospholipase C. (1215 aa)
	CRK	V-crk avian sarcoma virus CT10 oncogene homolog. (306 aa)
	PDGFA	Platelet-derived growth factor alpha polypeptide; Belongs to the PDGF/VEGF growth factor family. (150 aa)
	BCAR1	Breast cancer anti-estrogen resistance 1. (918 aa)
	NRAS	Neuroblastoma RAS viral (V-ras) oncogene homolog. (123 aa)
	CSDE1	Cold shock domain containing E1, RNA-binding. (796 aa)
	CRKL	V-crk avian sarcoma virus CT10 oncogene homolog-like. (369 aa)
	PIK3CB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1066 aa)
	RASA1	RAS p21 protein activator (GTPase activating protein) 1. (982 aa)
	SOS1	Uncharacterized protein. (1323 aa)
	A306_00011441	Fibronectin type-III domain-containing protein 3a-like, transcript variant X1. (1189 aa)
	PIK3R2	Phosphoinositide-3-kinase, regulatory subunit 2 (Beta). (727 aa)
	STAT3	Signal transducer and activator of transcription. (771 aa)
	STAT6	Signal transducer and activator of transcription. (908 aa)
	A306_00014977	Signal transducer and activator of transcription 5B. (703 aa)
	NEDD9	Neural cell expressed, developmentally down-regulated 9. (838 aa)
	A306_00002936	Apovitellenin-1; Protein component of the very low density lipoprotein (VLDL) of egg-laying females. Potent lipoprotein lipase inhibitor, preventing the loss of triglycerides from VLDL on their way from the liver to the growing oocytes. (106 aa)
	NCK2	Cytoplasmic protein. (380 aa)
	FNDC3A	Fibronectin type III domain containing 3A, transcript variant X1. (1199 aa)
	PDGFRA	Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1087 aa)
	KRAS	Uncharacterized protein. (197 aa)

Your Current Organism:

Columba livia

NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A306_00006107	CRKL	A0A2I0M3D4	A0A2I0LZB3	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	V-crk avian sarcoma virus CT10 oncogene homolog-like.	0.424
A306_00006107	CSDE1	A0A2I0M3D4	A0A2I0LZZ5	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Cold shock domain containing E1, RNA-binding.	0.430
A306_00006107	GRB2	A0A2I0M3D4	A0A2I0M7L1	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Growth factor receptor-bound protein 2.	0.957
A306_00006107	HRAS	A0A2I0M3D4	A0A2I0MI00	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Uncharacterized protein.	0.430
A306_00006107	KRAS	A0A2I0M3D4	A0A2I0MKD5	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Uncharacterized protein.	0.430
A306_00006107	NRAS	A0A2I0M3D4	A0A2I0LZZ9	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Neuroblastoma RAS viral (V-ras) oncogene homolog.	0.430
A306_00006107	PDGFB	A0A2I0M3D4	A0A2I0MJA9	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Platelet-derived growth factor beta polypeptide; Belongs to the PDGF/VEGF growth factor family.	0.410
A306_00006107	PDGFRA	A0A2I0M3D4	A0A2I0MMJ2	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.	0.674
A306_00006107	PDGFRB	A0A2I0M3D4	A0A2I0M9Z9	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.850
A306_00006107	PIK3CA	A0A2I0M3D4	A0A2I0MBJ9	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.652
A306_00006107	PIK3CB	A0A2I0M3D4	A0A2I0LW23	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.537
A306_00006107	PIK3R2	A0A2I0M3D4	A0A2I0LQ03	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Phosphoinositide-3-kinase, regulatory subunit 2 (Beta).	0.535
A306_00006107	PLCG1	A0A2I0M3D4	A0A2I0M273	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Phosphoinositide phospholipase C.	0.408
A306_00006107	PTPN11	A0A2I0M3D4	A0A2I0M8A8	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Protein tyrosine phosphatase, non-receptor type 11.	0.901
A306_00006107	SOS1	A0A2I0M3D4	A0A2I0LT24	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Uncharacterized protein.	0.937
A306_00006107	SRC	A0A2I0M3D4	A0A2I0M2A8	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	SRC proto-oncogene, non-receptor tyrosine kinase.	0.629
A306_00006107	STAT3	A0A2I0M3D4	A0A2I0LK33	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Signal transducer and activator of transcription.	0.688
A306_00014977	PDGFB	A0A2I0LHC5	A0A2I0MJA9	Signal transducer and activator of transcription 5B.	Platelet-derived growth factor beta polypeptide; Belongs to the PDGF/VEGF growth factor family.	0.436
A306_00014977	PDGFRA	A0A2I0LHC5	A0A2I0MMJ2	Signal transducer and activator of transcription 5B.	Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.	0.499
A306_00014977	PDGFRB	A0A2I0LHC5	A0A2I0M9Z9	Signal transducer and activator of transcription 5B.	Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.593