STRINGSTRING
NSDHL NSDHL PPAPDC2 PPAPDC2 HSD17B7 HSD17B7 DHCR7 DHCR7 SREBF2 SREBF2 A306_00002460 A306_00002460 A306_00002566 A306_00002566 ARV1 ARV1 ACAT2 ACAT2 GGPS1 GGPS1 SQLE SQLE MVD MVD FDPS FDPS HMGCS1 HMGCS1 SC5D SC5D SREBF1 SREBF1 FDFT1 FDFT1 LSS LSS HMGCR HMGCR PPAPDC3 PPAPDC3 LBR LBR MVK MVK DHCR24 DHCR24
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NSDHLNAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family. (346 aa)
PPAPDC2Phosphatidic acid phosphatase type 2 domain containing 2. (203 aa)
HSD17B7Hydroxysteroid (17-beta) dehydrogenase 7. (306 aa)
DHCR77-dehydrocholesterol reductase. (475 aa)
SREBF2Sterol regulatory element binding transcription factor 2. (448 aa)
A306_00002460Isopentenyl-diphosphate Delta-isomerase 1. (227 aa)
A306_00002566Lanosterol 14-alpha demethylase. (274 aa)
ARV1ARV1 homolog, fatty acid homeostatsis modulator. (199 aa)
ACAT2Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (340 aa)
GGPS1Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. (299 aa)
SQLESqualene epoxidase. (572 aa)
MVDDiphosphomevalonate decarboxylase. (356 aa)
FDPSFarnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. (304 aa)
HMGCS13-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (522 aa)
SC5DSterol-C5-desaturase; Belongs to the sterol desaturase family. (289 aa)
SREBF1Sterol regulatory element binding transcription factor 1. (1025 aa)
FDFT1Farnesyl-diphosphate farnesyltransferase 1. (390 aa)
LSSTerpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (634 aa)
HMGCR3-hydroxy-3-methylglutaryl coenzyme A reductase. (882 aa)
PPAPDC3Phosphatidic acid phosphatase type 2 domain containing 3. (271 aa)
LBRLamin B receptor. (608 aa)
MVKMevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (397 aa)
DHCR2424-dehydrocholesterol reductase. (427 aa)
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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