20 items (Columba livia) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RPS6KA2	Ribosomal protein S6 kinase. (733 aa)
	A306_00014015	Mitogen-activated protein kinase. (167 aa)
	A306_00001775	KIAA1468 ortholog. (1071 aa)
	PPP4R1	Protein phosphatase 4, regulatory subunit 1. (935 aa)
	RPS6KA5	Ribosomal protein S6 kinase, 90kDa, polypeptide 5. (765 aa)
	PPP4R4	Protein phosphatase 4, regulatory subunit 4. (875 aa)
	RPS6KA3	Non-specific serine/threonine protein kinase. (707 aa)
	A306_00007180	Mitogen-activated protein kinase. (221 aa)
	A306_00007179	Mitogen-activated protein kinase 11. (75 aa)
	MAPK1	Mitogen-activated protein kinase 1, transcript variant X2. (263 aa)
	A306_00008325	Serine/threonine-protein phosphatase 4 regulatory subunit 1-like. (551 aa)
	VRK3	Vaccinia related kinase 3. (332 aa)
	DUSP6	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (353 aa)
	DUSP7	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (317 aa)
	DUSP3	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (184 aa)
	RPS6KA1	Ribosomal protein S6 kinase, 90kDa, polypeptide 1. (773 aa)
	A306_00014013	Mitogen-activated protein kinase. (182 aa)
	MAPK15	Mitogen-activated protein kinase. (524 aa)
	FNBP4	WW domain-containing protein. (479 aa)
	PPP2R1A	Protein phosphatase 2, regulatory subunit A, alpha. (503 aa)

Your Current Organism:

Columba livia

NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A306_00007179	DUSP6	A0A2I0MHA4	A0A2I0LWD7	Mitogen-activated protein kinase 11.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.526
A306_00007179	DUSP7	A0A2I0MHA4	A0A2I0LSN7	Mitogen-activated protein kinase 11.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.526
A306_00007179	MAPK1	A0A2I0MHA4	A0A2I0M868	Mitogen-activated protein kinase 11.	Mitogen-activated protein kinase 1, transcript variant X2.	0.453
A306_00007179	RPS6KA5	A0A2I0MHA4	A0A2I0MQ34	Mitogen-activated protein kinase 11.	Ribosomal protein S6 kinase, 90kDa, polypeptide 5.	0.631
A306_00007180	DUSP3	A0A2I0MHJ1	A0A2I0LNC1	Mitogen-activated protein kinase.	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.933
A306_00007180	DUSP6	A0A2I0MHJ1	A0A2I0LWD7	Mitogen-activated protein kinase.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.526
A306_00007180	DUSP7	A0A2I0MHJ1	A0A2I0LSN7	Mitogen-activated protein kinase.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.827
A306_00007180	MAPK1	A0A2I0MHJ1	A0A2I0M868	Mitogen-activated protein kinase.	Mitogen-activated protein kinase 1, transcript variant X2.	0.944
A306_00007180	RPS6KA5	A0A2I0MHJ1	A0A2I0MQ34	Mitogen-activated protein kinase.	Ribosomal protein S6 kinase, 90kDa, polypeptide 5.	0.961
A306_00014013	A306_00014015	A0A2I0LKK4	R7VXR9	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.900
A306_00014013	DUSP3	A0A2I0LKK4	A0A2I0LNC1	Mitogen-activated protein kinase.	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.933
A306_00014013	DUSP6	A0A2I0LKK4	A0A2I0LWD7	Mitogen-activated protein kinase.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.526
A306_00014013	DUSP7	A0A2I0LKK4	A0A2I0LSN7	Mitogen-activated protein kinase.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.827
A306_00014013	MAPK1	A0A2I0LKK4	A0A2I0M868	Mitogen-activated protein kinase.	Mitogen-activated protein kinase 1, transcript variant X2.	0.943
A306_00014013	RPS6KA5	A0A2I0LKK4	A0A2I0MQ34	Mitogen-activated protein kinase.	Ribosomal protein S6 kinase, 90kDa, polypeptide 5.	0.961
A306_00014015	A306_00014013	R7VXR9	A0A2I0LKK4	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.900
A306_00014015	DUSP6	R7VXR9	A0A2I0LWD7	Mitogen-activated protein kinase.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.526
A306_00014015	DUSP7	R7VXR9	A0A2I0LSN7	Mitogen-activated protein kinase.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.526
A306_00014015	MAPK1	R7VXR9	A0A2I0M868	Mitogen-activated protein kinase.	Mitogen-activated protein kinase 1, transcript variant X2.	0.453
A306_00014015	RPS6KA5	R7VXR9	A0A2I0MQ34	Mitogen-activated protein kinase.	Ribosomal protein S6 kinase, 90kDa, polypeptide 5.	0.631