75 items (Columba livia) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NFAT5	Nuclear factor of activated T-cells 5, tonicity-responsive, transcript variant X2. (1455 aa)
	GAB2	GRB2-associated binding protein 2. (643 aa)
	VAV2	Vav 2 guanine nucleotide exchange factor. (878 aa)
	CUL1	Cullin 1; Belongs to the cullin family. (776 aa)
	MAP3K1	Mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase. (1317 aa)
	TAB3	TGF-beta activated kinase 1/MAP3K7 binding protein 3, transcript variant X1. (680 aa)
	NFATC2	Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2. (507 aa)
	PSMA7	Proteasome endopeptidase complex. (245 aa)
	GRB2	Growth factor receptor-bound protein 2. (250 aa)
	NFATC3	Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3. (999 aa)
	NFKB1	Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1. (959 aa)
	PPP3CA	Serine/threonine-protein phosphatase. (460 aa)
	PPP3R1	Protein phosphatase 3, regulatory subunit B, alpha. (160 aa)
	RPS27A	Ribosomal protein S27a. (156 aa)
	PSME4	Proteasome (Prosome, macropain) activator subunit 4. (1823 aa)
	WDR92	WD repeat domain 92. (309 aa)
	MAPK9	Mitogen-activated protein kinase. (424 aa)
	VAV3	Vav 3 guanine nucleotide exchange factor. (834 aa)
	PPP3CB	Serine/threonine-protein phosphatase. (439 aa)
	MAPK10	Mitogen-activated protein kinase. (484 aa)
	TEC	Tyrosine-protein kinase. (633 aa)
	TXK	Tyrosine-protein kinase. (528 aa)
	KRAS	Uncharacterized protein. (197 aa)
	GRAP2	GRB2-related adaptor protein 2, transcript variant X1. (296 aa)
	TAB1	TGF-beta activated kinase 1/MAP3K7 binding protein 1. (498 aa)
	A306_00014331	Ig heavy chain Mem5. (142 aa)
	A306_00001163	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1300 aa)
	LYN	Tyrosine-protein kinase. (513 aa)
	MAP3K7	Mitogen-activated protein kinase kinase kinase 7, transcript variant X1. (194 aa)
	TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2. (688 aa)
	FOS	FBJ murine osteosarcoma viral oncogene homolog. (158 aa)
	MAP3K20	Mitogen-activated protein kinase kinase kinase MLT. (450 aa)
	PSMA1	Proteasome subunit alpha type. (297 aa)
	HRAS	Uncharacterized protein. (189 aa)
	ANKHD1	Ankyrin repeat and KH domain containing 1. (1620 aa)
	LCP2	Lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa). (354 aa)
	SKP1	S-phase kinase-associated protein 1, transcript variant X1; Belongs to the SKP1 family. (163 aa)
	FOSL2	FOS-like antigen 2. (285 aa)
	PSMD10	Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 10. (217 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1052 aa)
	JUN	Jun proto-oncogene; Belongs to the bZIP family. (338 aa)
	BCL10	B-cell CLL/lymphoma 10. (214 aa)
	TRAF6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa)
	A306_00000373	CASPASE_P20 domain-containing protein. (209 aa)
	A306_00000420	Uncharacterized protein. (139 aa)
	A306_00014898	Putative nuclease HARBI1. (371 aa)
	VAV1	Vav 1 guanine nucleotide exchange factor. (690 aa)
	PPP3CC	Serine/threonine-protein phosphatase. (504 aa)
	A306_00000409	Uncharacterized protein. (480 aa)
	A306_00014498	Dual specificity mitogen-activated protein kinase kinase hemipterous-like. (510 aa)
	A306_00014207	Ig heavy chain Mem5. (300 aa)
	MALT1	MALT1 paracaspase. (474 aa)
	SHC1	SHC (Src homology 2 domain containing) transforming protein 1. (345 aa)
	PSMD1	Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 1. (951 aa)
	A306_00014332	Putative LOC102084667. (107 aa)
	A306_00013655	Mucosa-associated lymphoid tissue lymphoma translocation protein 1-like. (514 aa)
	MAP2K4	Mitogen-activated protein kinase kinase 4. (725 aa)
	KXD1	KxDL motif containing 1. (135 aa)
	PIK3R2	Phosphoinositide-3-kinase, regulatory subunit 2 (Beta). (727 aa)
	BTK	Tyrosine-protein kinase. (692 aa)
	FBXW11	F-box and WD repeat domain containing 11, transcript variant X3. (531 aa)
	ECSCR	Endothelial cell surface expressed chemotaxis and apoptosis regulator. (248 aa)
	NFATC1	Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1, transcript variant X1. (811 aa)
	SOS1	Uncharacterized protein. (1323 aa)
	PAK2	Non-specific serine/threonine protein kinase. (525 aa)
	PIK3CB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1066 aa)
	ITK	Tyrosine-protein kinase. (631 aa)
	PDPK1	3-phosphoinositide dependent protein kinase 1. (524 aa)
	MAPK8	Mitogen-activated protein kinase. (427 aa)
	CSDE1	Cold shock domain containing E1, RNA-binding. (796 aa)
	NRAS	Neuroblastoma RAS viral (V-ras) oncogene homolog. (123 aa)
	PLCG2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1245 aa)
	CARD11	Caspase recruitment domain family, member 11. (1169 aa)
	SPNS3	MFS domain-containing protein. (498 aa)
	UBE2V1	Ubiquitin-conjugating enzyme E2 variant 1. (154 aa)

Your Current Organism:

Columba livia

NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A306_00000373	BCL10	A0A2I0LGF4	A0A2I0MDY1	CASPASE_P20 domain-containing protein.	B-cell CLL/lymphoma 10.	0.959
A306_00000373	CARD11	A0A2I0LGF4	A0A2I0M0X0	CASPASE_P20 domain-containing protein.	Caspase recruitment domain family, member 11.	0.876
A306_00000373	MAP3K20	A0A2I0LGF4	A0A2I0MJ01	CASPASE_P20 domain-containing protein.	Mitogen-activated protein kinase kinase kinase MLT.	0.440
A306_00000373	MAP3K7	A0A2I0LGF4	A0A2I0MUQ8	CASPASE_P20 domain-containing protein.	Mitogen-activated protein kinase kinase kinase 7, transcript variant X1.	0.530
A306_00000373	TAB2	A0A2I0LGF4	A0A2I0MTV7	CASPASE_P20 domain-containing protein.	TGF-beta activated kinase 1/MAP3K7 binding protein 2.	0.565
A306_00000373	TAB3	A0A2I0LGF4	A0A2I0M5L4	CASPASE_P20 domain-containing protein.	TGF-beta activated kinase 1/MAP3K7 binding protein 3, transcript variant X1.	0.463
A306_00000373	TRAF6	A0A2I0LGF4	A0A172PWX2	CASPASE_P20 domain-containing protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.852
A306_00000409	A306_00014207	A0A2I0LIU4	A0A2I0LJX4	Uncharacterized protein.	Ig heavy chain Mem5.	0.984
A306_00000409	GRB2	A0A2I0LIU4	A0A2I0M7L1	Uncharacterized protein.	Growth factor receptor-bound protein 2.	0.432
A306_00000409	LYN	A0A2I0LIU4	A0A2I0MVY9	Uncharacterized protein.	Tyrosine-protein kinase.	0.411
A306_00000420	A306_00014207	A0A2I0LHI9	A0A2I0LJX4	Uncharacterized protein.	Ig heavy chain Mem5.	0.686
A306_00001163	GRAP2	A0A2I0MXY9	A0A2I0MJS2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	GRB2-related adaptor protein 2, transcript variant X1.	0.764
A306_00001163	GRB2	A0A2I0MXY9	A0A2I0M7L1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Growth factor receptor-bound protein 2.	0.850
A306_00001163	LCP2	A0A2I0MXY9	A0A2I0M9Z1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa).	0.772
A306_00001163	PAK2	A0A2I0MXY9	A0A2I0LUS9	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Non-specific serine/threonine protein kinase.	0.443
A306_00001163	PIK3CA	A0A2I0MXY9	A0A2I0MBJ9	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.741
A306_00001163	PIK3CB	A0A2I0MXY9	A0A2I0LW23	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.741
A306_00001163	PIK3R2	A0A2I0MXY9	A0A2I0LQ03	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Phosphoinositide-3-kinase, regulatory subunit 2 (Beta).	0.729
A306_00001163	PLCG2	A0A2I0MXY9	A0A2I0M0A9	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.902
A306_00001163	PPP3CA	A0A2I0MXY9	A0A2I0M904	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Serine/threonine-protein phosphatase.	0.902