31 items (Columba livia) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LCP2	Lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa). (354 aa)
	A306_00001163	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1300 aa)
	FOS	FBJ murine osteosarcoma viral oncogene homolog. (158 aa)
	KRAS	Uncharacterized protein. (197 aa)
	GRAP2	GRB2-related adaptor protein 2, transcript variant X1. (296 aa)
	HRAS	Uncharacterized protein. (189 aa)
	MAPK10	Mitogen-activated protein kinase. (484 aa)
	VAV3	Vav 3 guanine nucleotide exchange factor. (834 aa)
	JUN	Jun proto-oncogene; Belongs to the bZIP family. (338 aa)
	FOSL2	FOS-like antigen 2. (285 aa)
	ANKHD1	Ankyrin repeat and KH domain containing 1. (1620 aa)
	A306_00000420	Uncharacterized protein. (139 aa)
	A306_00014898	Putative nuclease HARBI1. (371 aa)
	VAV1	Vav 1 guanine nucleotide exchange factor. (690 aa)
	A306_00000409	Uncharacterized protein. (480 aa)
	A306_00014498	Dual specificity mitogen-activated protein kinase kinase hemipterous-like. (510 aa)
	A306_00014207	Ig heavy chain Mem5. (300 aa)
	SHC1	SHC (Src homology 2 domain containing) transforming protein 1. (345 aa)
	A306_00014332	Putative LOC102084667. (107 aa)
	MAP2K4	Mitogen-activated protein kinase kinase 4. (725 aa)
	SOS1	Uncharacterized protein. (1323 aa)
	PAK2	Non-specific serine/threonine protein kinase. (525 aa)
	MAPK8	Mitogen-activated protein kinase. (427 aa)
	CSDE1	Cold shock domain containing E1, RNA-binding. (796 aa)
	NRAS	Neuroblastoma RAS viral (V-ras) oncogene homolog. (123 aa)
	PLCG2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1245 aa)
	SPNS3	MFS domain-containing protein. (498 aa)
	VAV2	Vav 2 guanine nucleotide exchange factor. (878 aa)
	MAP3K1	Mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase. (1317 aa)
	GRB2	Growth factor receptor-bound protein 2. (250 aa)
	MAPK9	Mitogen-activated protein kinase. (424 aa)

Your Current Organism:

Columba livia

NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A306_00000409	A306_00014207	A0A2I0LIU4	A0A2I0LJX4	Uncharacterized protein.	Ig heavy chain Mem5.	0.984
A306_00000409	GRB2	A0A2I0LIU4	A0A2I0M7L1	Uncharacterized protein.	Growth factor receptor-bound protein 2.	0.432
A306_00000420	A306_00014207	A0A2I0LHI9	A0A2I0LJX4	Uncharacterized protein.	Ig heavy chain Mem5.	0.686
A306_00001163	GRAP2	A0A2I0MXY9	A0A2I0MJS2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	GRB2-related adaptor protein 2, transcript variant X1.	0.764
A306_00001163	GRB2	A0A2I0MXY9	A0A2I0M7L1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Growth factor receptor-bound protein 2.	0.850
A306_00001163	LCP2	A0A2I0MXY9	A0A2I0M9Z1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa).	0.772
A306_00001163	PAK2	A0A2I0MXY9	A0A2I0LUS9	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Non-specific serine/threonine protein kinase.	0.443
A306_00001163	PLCG2	A0A2I0MXY9	A0A2I0M0A9	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.902
A306_00001163	SHC1	A0A2I0MXY9	A0A2I0LM13	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	SHC (Src homology 2 domain containing) transforming protein 1.	0.586
A306_00001163	SOS1	A0A2I0MXY9	A0A2I0LT24	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Uncharacterized protein.	0.515
A306_00001163	VAV1	A0A2I0MXY9	A0A2I0LI76	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Vav 1 guanine nucleotide exchange factor.	0.495
A306_00001163	VAV2	A0A2I0MXY9	A0A2I0M3R7	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Vav 2 guanine nucleotide exchange factor.	0.495
A306_00001163	VAV3	A0A2I0MXY9	A0A2I0ME16	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Vav 3 guanine nucleotide exchange factor.	0.495
A306_00014207	A306_00000409	A0A2I0LJX4	A0A2I0LIU4	Ig heavy chain Mem5.	Uncharacterized protein.	0.984
A306_00014207	A306_00000420	A0A2I0LJX4	A0A2I0LHI9	Ig heavy chain Mem5.	Uncharacterized protein.	0.686
A306_00014207	A306_00014332	A0A2I0LJX4	A0A2I0LN48	Ig heavy chain Mem5.	Putative LOC102084667.	0.856
A306_00014207	A306_00014898	A0A2I0LJX4	A0A2I0LHZ1	Ig heavy chain Mem5.	Putative nuclease HARBI1.	0.470
A306_00014332	A306_00014207	A0A2I0LN48	A0A2I0LJX4	Putative LOC102084667.	Ig heavy chain Mem5.	0.856
A306_00014332	GRB2	A0A2I0LN48	A0A2I0M7L1	Putative LOC102084667.	Growth factor receptor-bound protein 2.	0.432
A306_00014498	JUN	A0A2I0LJ18	A0A2I0MBW5	Dual specificity mitogen-activated protein kinase kinase hemipterous-like.	Jun proto-oncogene; Belongs to the bZIP family.	0.621