STRINGSTRING
A306_00015353 A306_00015353 PDE2A PDE2A GRK2 GRK2 GRK6 GRK6 GLP2R GLP2R ADRB3 ADRB3 GCGR GCGR A306_00011899 A306_00011899 RAMP2 RAMP2 A306_00012518 A306_00012518 A306_00012727 A306_00012727 A306_00012728 A306_00012728 IAPP IAPP PDE3A PDE3A ARR3 ARR3 GNGT2 GNGT2 GIP GIP CRHR1 CRHR1 A306_00011175 A306_00011175 DRD1 DRD1 ADRB2 ADRB2 HTR4 HTR4 A306_00012199 A306_00012199 GNG13 GNG13 PTGER4 PTGER4 RXFP1 RXFP1 NPSR1 NPSR1 GPR83 GPR83 POMC POMC HRH2 HRH2 A306_00010400 A306_00010400 HTR7 HTR7 ADORA2B ADORA2B ADORA2A ADORA2A TSHB TSHB PRKAR1B PRKAR1B GPER1 GPER1 PDE8B PDE8B GHRH GHRH A306_00010232 A306_00010232 HTR6 HTR6 GNB1 GNB1 GPR21 GPR21 RAMP3 RAMP3 MC3R MC3R GNAS GNAS PRKAR1A PRKAR1A ADRBK2 ADRBK2 GPR27 GPR27 PRKAR2A PRKAR2A GLP1R GLP1R GNB4 GNB4 GPR52 GPR52 GNG12 GNG12 INSL5 INSL5 PDE8A PDE8A GNB5 GNB5 PRKACB PRKACB NPS NPS GRK5 GRK5 ADRB1 ADRB1 A306_00007923 A306_00007923 GPR39 GPR39 SCTR SCTR PRKAR2B PRKAR2B FSHB FSHB PTH PTH ADM ADM CALCB CALCB PDE3B PDE3B CALCRL CALCRL GCG GCG A306_00003898 A306_00003898 FN1 FN1 PDE1A PDE1A A306_00003978 A306_00003978 GPR85 GPR85 PTHLH PTHLH GNB3 GNB3 DRD5 DRD5 A306_00003297 A306_00003297 TSHR TSHR GPHB5 GPHB5 PTGDR PTGDR PTGER2 PTGER2 GPR176 GPR176 GNG2 GNG2 A306_00002580 A306_00002580 PTH1R PTH1R VIPR2 VIPR2 CALCR CALCR ADCYAP1R1 ADCYAP1R1 VIPR1 VIPR1 GHRHR GHRHR A306_00002397 A306_00002397 CRHR2 CRHR2 GPR15 GPR15 GPR63 GPR63 GNG4 GNG4 PDE10A PDE10A PDE7B PDE7B CRH CRH PDE7A PDE7A MC5R MC5R MC4R MC4R A306_00001182 A306_00001182 ADCYAP1 ADCYAP1 THAP1 THAP1 GNG10 GNG10 MC2R MC2R MC1R MC1R
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A306_00015353G-protein coupled receptor 20; Belongs to the G-protein coupled receptor 1 family. (350 aa)
PDE2APDEase domain-containing protein; Belongs to the cyclic nucleotide phosphodiesterase family. (309 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (508 aa)
GRK6G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (571 aa)
GLP2RGlucagon-like peptide 2 receptor; Belongs to the G-protein coupled receptor 2 family. (529 aa)
ADRB3Adrenoceptor beta 3; Belongs to the G-protein coupled receptor 1 family. (374 aa)
GCGRGlucagon receptor; Belongs to the G-protein coupled receptor 2 family. (272 aa)
A306_00011899Parathyroid hormone/parathyroid hormone-related peptide receptor-like; Belongs to the G-protein coupled receptor 2 family. (548 aa)
RAMP2Receptor (G protein-coupled) activity modifying protein 2. (175 aa)
A306_00012518Glucagon receptor; Belongs to the G-protein coupled receptor 2 family. (433 aa)
A306_00012727Putative G-protein coupled receptor 83; Belongs to the G-protein coupled receptor 1 family. (412 aa)
A306_00012728Putative G-protein coupled receptor 83; Belongs to the G-protein coupled receptor 1 family. (354 aa)
IAPPIslet amyloid polypeptide. (86 aa)
PDE3APhosphodiesterase. (794 aa)
ARR3Arrestin 3, retinal (X-arrestin). (362 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
GIPGastric inhibitory polypeptide. (148 aa)
CRHR1Corticotropin releasing hormone receptor 1; Belongs to the G-protein coupled receptor 2 family. (417 aa)
A306_00011175Vasoactive intestinal polypeptide receptor 1; Belongs to the G-protein coupled receptor 2 family. (424 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (451 aa)
ADRB2Adrenoceptor beta 2, surface. (444 aa)
HTR45-hydroxytryptamine (Serotonin) receptor 4, G protein-coupled; Belongs to the G-protein coupled receptor 1 family. (387 aa)
A306_00012199D(1) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (444 aa)
GNG13Guanine nucleotide binding protein (G protein), gamma 13. (67 aa)
PTGER4Prostaglandin E receptor 4 (Subtype EP4); Belongs to the G-protein coupled receptor 1 family. (505 aa)
RXFP1Relaxin/insulin-like family peptide receptor 1. (766 aa)
NPSR1Neuropeptide S receptor 1; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (349 aa)
GPR83G protein-coupled receptor 83; Belongs to the G-protein coupled receptor 1 family. (423 aa)
POMCProopiomelanocortin. (220 aa)
HRH2Histamine receptor H2; Belongs to the G-protein coupled receptor 1 family. (368 aa)
A306_00010400D(1)-like dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (454 aa)
HTR75-hydroxytryptamine (Serotonin) receptor 7, adenylate cyclase-coupled. (362 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (352 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (436 aa)
TSHBThyroid stimulating hormone, beta, transcript variant X1. (134 aa)
PRKAR1BProtein kinase, cAMP-dependent, regulatory, type I, beta. (381 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (357 aa)
PDE8BPhosphodiesterase. (774 aa)
GHRHGrowth hormone releasing hormone. (171 aa)
A306_00010232Beta-arrestin-1. (326 aa)
HTR65-hydroxytryptamine (Serotonin) receptor 6, G protein-coupled; Belongs to the G-protein coupled receptor 1 family. (433 aa)
GNB1Guanine nucleotide binding protein (G protein), beta polypeptide 1. (340 aa)
GPR21G protein-coupled receptor 21. (237 aa)
RAMP3Receptor (G protein-coupled) activity modifying protein 3. (135 aa)
MC3RMelanocortin 3 receptor. (325 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha. (305 aa)
PRKAR1AProtein kinase, cAMP-dependent, regulatory, type I, alpha, transcript variant X1. (382 aa)
ADRBK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (646 aa)
GPR27G protein-coupled receptor 27. (364 aa)
PRKAR2AProtein kinase, cAMP-dependent, regulatory, type II, alpha. (378 aa)
GLP1RGlucagon-like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (426 aa)
GNB4Guanine nucleotide binding protein (G protein), beta polypeptide 4. (340 aa)
GPR52G protein-coupled receptor 52; Belongs to the G-protein coupled receptor 1 family. (361 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
INSL5Insulin-like 5. (137 aa)
PDE8APhosphodiesterase. (854 aa)
GNB5Guanine nucleotide binding protein (G protein), beta 5. (388 aa)
PRKACBProtein kinase, cAMP-dependent, catalytic, beta, transcript variant X1; Belongs to the protein kinase superfamily. (398 aa)
NPSNeuropeptide S. (121 aa)
GRK5G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (590 aa)
ADRB1Adrenoceptor beta 1. (476 aa)
A306_00007923Putative LOC102098037. (180 aa)
GPR39G protein-coupled receptor 39; Belongs to the G-protein coupled receptor 1 family. (459 aa)
SCTRSecretin receptor; Belongs to the G-protein coupled receptor 2 family. (450 aa)
PRKAR2BProtein kinase, cAMP-dependent, regulatory, type II, beta. (324 aa)
FSHBFollicle stimulating hormone, beta polypeptide. (131 aa)
PTHParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (119 aa)
ADMAdrenomedullin. (257 aa)
CALCBCalcitonin-related polypeptide beta, transcript variant X1. (138 aa)
PDE3BPhosphodiesterase. (762 aa)
CALCRLCalcitonin receptor-like; Belongs to the G-protein coupled receptor 2 family. (450 aa)
GCGGlucagon. (206 aa)
A306_00003898Prolyl endopeptidase FAP; Belongs to the peptidase S9B family. (759 aa)
FN1Fibronectin 1. (2375 aa)
PDE1APhosphodiesterase. (661 aa)
A306_00003978Dual 3',5'-cyclic-AMP and-GMP phosphodiesterase 11A. (171 aa)
GPR85G protein-coupled receptor 85. (370 aa)
PTHLHParathyroid hormone-like hormone, transcript variant X1. (177 aa)
GNB3Guanine nucleotide binding protein (G protein), beta polypeptide 3. (340 aa)
DRD5Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family. (512 aa)
A306_000032975-hydroxytryptamine receptor 7-like; Belongs to the G-protein coupled receptor 1 family. (254 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (759 aa)
GPHB5Glycoprotein hormone beta 5. (131 aa)
PTGDRProstaglandin D2 receptor (DP). (277 aa)
PTGER2Prostaglandin E receptor 2 (Subtype EP2), 53kDa. (319 aa)
GPR176G protein-coupled receptor 176. (529 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
A306_00002580Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
PTH1RParathyroid hormone 1 receptor, transcript variant X1; Belongs to the G-protein coupled receptor 2 family. (576 aa)
VIPR2Vasoactive intestinal peptide receptor 2; Belongs to the G-protein coupled receptor 2 family. (401 aa)
CALCRCalcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (469 aa)
ADCYAP1R1Adenylate cyclase activating polypeptide 1 (Pituitary) receptor type I; Belongs to the G-protein coupled receptor 2 family. (483 aa)
VIPR1Vasoactive intestinal peptide receptor 1; Belongs to the G-protein coupled receptor 2 family. (448 aa)
GHRHRGrowth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (424 aa)
A306_00002397Vasoactive intestinal polypeptide receptor; Belongs to the G-protein coupled receptor 2 family. (425 aa)
CRHR2Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. (312 aa)
GPR15G protein-coupled receptor 15; Belongs to the G-protein coupled receptor 1 family. (370 aa)
GPR63G protein-coupled receptor 63. (419 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
PDE10APhosphodiesterase. (793 aa)
PDE7BPhosphodiesterase. (447 aa)
CRHCorticotropin releasing hormone. (172 aa)
PDE7APhosphodiesterase. (458 aa)
MC5RMelanocortin 5 receptor, transcript variant X1. (325 aa)
MC4RMelanocortin 4 receptor. (331 aa)
A306_00001182G-protein coupled receptor 20; Belongs to the G-protein coupled receptor 1 family. (318 aa)
ADCYAP1Adenylate cyclase activating polypeptide 1 (Pituitary). (134 aa)
THAP1THAP domain containing, apoptosis associated protein 1. (238 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
MC2RMelanocortin 2 receptor (Adrenocorticotropic hormone). (319 aa)
MC1RMelanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. (313 aa)
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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