STRINGSTRING
A306_00015223 A306_00015223 POLR2H POLR2H GTF2F1 GTF2F1 POLR2I POLR2I POLR2E POLR2E PTBP1 PTBP1 SHC1 SHC1 HNRNPM HNRNPM FRS3 FRS3 FGF8 FGF8 MKNK2 MKNK2 POLR2C POLR2C FGF17 FGF17 A306_00011441 A306_00011441 FGF18 FGF18 SOS1 SOS1 FGF1 FGF1 TIA1 TIA1 POLR2D POLR2D CBL CBL POLR2B POLR2B MKNK1 MKNK1 CSDE1 CSDE1 NRAS NRAS POLR2J POLR2J A306_00006107 A306_00006107 A306_00009263 A306_00009263 NCBP1 NCBP1 PTBP3 PTBP3 GRB2 GRB2 ESRP2 ESRP2 PTPN11 PTPN11 RPS27A RPS27A FGF16 FGF16 PIK3CA PIK3CA FNDC3B FNDC3B A306_00007698 A306_00007698 FGF9 FGF9 FGF7 FGF7 PTBP2 PTBP2 FGFR2 FGFR2 TIAL1 TIAL1 FGF5 FGF5 GAB1 GAB1 POLR2L POLR2L HRAS HRAS FGF4 FGF4 FGF3 FGF3 RBFOX2 RBFOX2 FGF6 FGF6 KRAS KRAS BRAF BRAF FGF23 FGF23 FGF20 FGF20 FGFBP2 FGFBP2 FGFBP1 FGFBP1 FNDC3A FNDC3A GTF2F2 GTF2F2 SPRY2 SPRY2 POLR2K POLR2K ESRP1 ESRP1 FRS2 FRS2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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A306_00015223Putative LOC102091525. (404 aa)
POLR2HPolymerase (RNA) II (DNA directed) polypeptide H. (114 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (214 aa)
POLR2IPolymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa. (90 aa)
POLR2EPolymerase (RNA) II (DNA directed) polypeptide E, 25kDa. (139 aa)
PTBP1Polypyrimidine tract binding protein 1. (574 aa)
SHC1SHC (Src homology 2 domain containing) transforming protein 1. (345 aa)
HNRNPMHeterogeneous nuclear ribonucleoprotein M. (593 aa)
FRS3Fibroblast growth factor receptor substrate 3. (469 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
MKNK2MAP kinase interacting serine/threonine kinase 2. (246 aa)
POLR2CPolymerase (RNA) II (DNA directed) polypeptide C, 33kDa. (244 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (199 aa)
A306_00011441Fibronectin type-III domain-containing protein 3a-like, transcript variant X1. (1189 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
SOS1Uncharacterized protein. (1323 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
TIA1TIA1 cytotoxic granule-associated RNA binding protein. (401 aa)
POLR2DPolymerase (RNA) II (DNA directed) polypeptide D. (161 aa)
CBLCbl proto-oncogene, E3 ubiquitin protein ligase. (909 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1167 aa)
MKNK1MAP kinase interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (438 aa)
CSDE1Cold shock domain containing E1, RNA-binding. (796 aa)
NRASNeuroblastoma RAS viral (V-ras) oncogene homolog. (123 aa)
POLR2JPolymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa. (148 aa)
A306_00006107Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
A306_00009263Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (138 aa)
NCBP1Nuclear cap binding protein subunit 1, 80kDa. (772 aa)
PTBP3Polypyrimidine tract binding protein 3. (197 aa)
GRB2Growth factor receptor-bound protein 2. (250 aa)
ESRP2Epithelial splicing regulatory protein 2, transcript variant X1. (729 aa)
PTPN11Protein tyrosine phosphatase, non-receptor type 11. (587 aa)
RPS27ARibosomal protein S27a. (156 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (123 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1052 aa)
FNDC3BUncharacterized protein. (1154 aa)
A306_00007698Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (161 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
PTBP2Polypyrimidine tract binding protein 2. (349 aa)
FGFR2Fibroblast growth factor receptor. (843 aa)
TIAL1TIA1 cytotoxic granule-associated RNA binding protein-like 1, transcript variant X1. (384 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (238 aa)
GAB1GRB2-associated binding protein 1. (718 aa)
POLR2LPolymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa. (67 aa)
HRASUncharacterized protein. (189 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (157 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (231 aa)
RBFOX2RNA binding protein fox-1 homolog; RNA-binding protein that regulates alternative splicing events. (384 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
KRASUncharacterized protein. (197 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase, transcript variant X1. (754 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (254 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (122 aa)
FGFBP2Fibroblast growth factor binding protein 2. (208 aa)
FGFBP1Fibroblast growth factor binding protein 1. (238 aa)
FNDC3AFibronectin type III domain containing 3A, transcript variant X1. (1199 aa)
GTF2F2General transcription factor IIF, polypeptide 2, 30kDa, transcript variant X2. (322 aa)
SPRY2Sprouty RTK signaling antagonist 2. (313 aa)
POLR2KPolymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa. (58 aa)
ESRP1Epithelial splicing regulatory protein 1. (404 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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