13 items (Columba livia) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FOXO3	Forkhead box O3. (535 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	KRAS	Uncharacterized protein. (197 aa)
	HRAS	Uncharacterized protein. (189 aa)
	PTPRJ	Protein tyrosine phosphatase, receptor type, J. (923 aa)
	FLT3	Fms-related tyrosine kinase 3. (997 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1052 aa)
	GRB2	Growth factor receptor-bound protein 2. (250 aa)
	GAB2	GRB2-associated binding protein 2. (643 aa)
	NRAS	Neuroblastoma RAS viral (V-ras) oncogene homolog. (123 aa)
	CSDE1	Cold shock domain containing E1, RNA-binding. (796 aa)
	SOS1	Uncharacterized protein. (1323 aa)
	SLA2	Src-like-adaptor 2. (266 aa)

Your Current Organism:

Columba livia

NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT3	FOXO3	A0A2I0MTK2	A0A2I0MVE4	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box O3.	0.986
AKT3	GRB2	A0A2I0MTK2	A0A2I0M7L1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Growth factor receptor-bound protein 2.	0.451
AKT3	PIK3CA	A0A2I0MTK2	A0A2I0MBJ9	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.970
CSDE1	FLT3	A0A2I0LZZ5	A0A2I0MCU9	Cold shock domain containing E1, RNA-binding.	Fms-related tyrosine kinase 3.	0.407
CSDE1	GRB2	A0A2I0LZZ5	A0A2I0M7L1	Cold shock domain containing E1, RNA-binding.	Growth factor receptor-bound protein 2.	0.623
CSDE1	PIK3CA	A0A2I0LZZ5	A0A2I0MBJ9	Cold shock domain containing E1, RNA-binding.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.695
CSDE1	SOS1	A0A2I0LZZ5	A0A2I0LT24	Cold shock domain containing E1, RNA-binding.	Uncharacterized protein.	0.676
FLT3	CSDE1	A0A2I0MCU9	A0A2I0LZZ5	Fms-related tyrosine kinase 3.	Cold shock domain containing E1, RNA-binding.	0.407
FLT3	GRB2	A0A2I0MCU9	A0A2I0M7L1	Fms-related tyrosine kinase 3.	Growth factor receptor-bound protein 2.	0.919
FLT3	HRAS	A0A2I0MCU9	A0A2I0MI00	Fms-related tyrosine kinase 3.	Uncharacterized protein.	0.407
FLT3	KRAS	A0A2I0MCU9	A0A2I0MKD5	Fms-related tyrosine kinase 3.	Uncharacterized protein.	0.407
FLT3	NRAS	A0A2I0MCU9	A0A2I0LZZ9	Fms-related tyrosine kinase 3.	Neuroblastoma RAS viral (V-ras) oncogene homolog.	0.407
FLT3	PIK3CA	A0A2I0MCU9	A0A2I0MBJ9	Fms-related tyrosine kinase 3.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.648
FLT3	PTPRJ	A0A2I0MCU9	A0A2I0MHW8	Fms-related tyrosine kinase 3.	Protein tyrosine phosphatase, receptor type, J.	0.699
FLT3	SOS1	A0A2I0MCU9	A0A2I0LT24	Fms-related tyrosine kinase 3.	Uncharacterized protein.	0.477
FOXO3	AKT3	A0A2I0MVE4	A0A2I0MTK2	Forkhead box O3.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.986
GAB2	GRB2	A0A2I0M2P4	A0A2I0M7L1	GRB2-associated binding protein 2.	Growth factor receptor-bound protein 2.	0.864
GRB2	AKT3	A0A2I0M7L1	A0A2I0MTK2	Growth factor receptor-bound protein 2.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.451
GRB2	CSDE1	A0A2I0M7L1	A0A2I0LZZ5	Growth factor receptor-bound protein 2.	Cold shock domain containing E1, RNA-binding.	0.623
GRB2	FLT3	A0A2I0M7L1	A0A2I0MCU9	Growth factor receptor-bound protein 2.	Fms-related tyrosine kinase 3.	0.919