18 items (Columba livia) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

Your Input:
	CD83	CD83 molecule. (217 aa)
	CCR6	Chemokine (C-C motif) receptor 6; Belongs to the G-protein coupled receptor 1 family. (361 aa)
	PFN4	Uncharacterized protein; Belongs to the profilin family. (108 aa)
	A306_00002661	Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
	CFL2	Cofilin 2 (Muscle); Belongs to the actin-binding proteins ADF family. (149 aa)
	A306_00003463	Toll-like receptor. (818 aa)
	A306_00003464	Toll-like receptor. (649 aa)
	IFNG	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (165 aa)
	ALB	Albumin. (609 aa)
	PDGFRB	Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1137 aa)
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
	PFN3	Profilin; Belongs to the profilin family. (134 aa)
	CD40LG	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (276 aa)
	CD40	CD40 molecule, TNF receptor superfamily member 5. (276 aa)
	PFN2	Profilin; Belongs to the profilin family. (245 aa)
	IL10	Interleukin 10. (176 aa)
	A306_00015372	Toll-like receptor. (380 aa)
	BCL2	B-cell CLL/lymphoma 2. (138 aa)

Your Current Organism:

Columba livia

NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A306_00002661	ALB	A0A2I0MQ77	A0A2I0MH12	Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Albumin.	0.540
A306_00002661	BCL2	A0A2I0MQ77	A0A2I0MW17	Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	B-cell CLL/lymphoma 2.	0.879
A306_00003463	IFNG	A0A2I0MMK2	A0A2I0MJ31	Toll-like receptor.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.466
A306_00003463	IL10	A0A2I0MMK2	A0A2I0LZX4	Toll-like receptor.	Interleukin 10.	0.478
A306_00003464	IFNG	A0A2I0MMJ4	A0A2I0MJ31	Toll-like receptor.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.466
A306_00003464	IL10	A0A2I0MMJ4	A0A2I0LZX4	Toll-like receptor.	Interleukin 10.	0.478
A306_00015372	IFNG	A0A2I0LG77	A0A2I0MJ31	Toll-like receptor.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.466
A306_00015372	IL10	A0A2I0LG77	A0A2I0LZX4	Toll-like receptor.	Interleukin 10.	0.478
ALB	A306_00002661	A0A2I0MH12	A0A2I0MQ77	Albumin.	Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.540
ALB	IFNG	A0A2I0MH12	A0A2I0MJ31	Albumin.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.421
ALB	IL10	A0A2I0MH12	A0A2I0LZX4	Albumin.	Interleukin 10.	0.420
BCL2	A306_00002661	A0A2I0MW17	A0A2I0MQ77	B-cell CLL/lymphoma 2.	Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.879
BCL2	IFNG	A0A2I0MW17	A0A2I0MJ31	B-cell CLL/lymphoma 2.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.440
BCL2	IL10	A0A2I0MW17	A0A2I0LZX4	B-cell CLL/lymphoma 2.	Interleukin 10.	0.464
CCR6	CD40LG	A0A2I0MU24	A0A2I0M4N3	Chemokine (C-C motif) receptor 6; Belongs to the G-protein coupled receptor 1 family.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.415
CCR6	CD83	A0A2I0MU24	A0A2I0MVR9	Chemokine (C-C motif) receptor 6; Belongs to the G-protein coupled receptor 1 family.	CD83 molecule.	0.524
CD40	CD40LG	A0A2I0M270	A0A2I0M4N3	CD40 molecule, TNF receptor superfamily member 5.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.991
CD40	CD83	A0A2I0M270	A0A2I0MVR9	CD40 molecule, TNF receptor superfamily member 5.	CD83 molecule.	0.709
CD40	IFNG	A0A2I0M270	A0A2I0MJ31	CD40 molecule, TNF receptor superfamily member 5.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.544
CD40	IL10	A0A2I0M270	A0A2I0LZX4	CD40 molecule, TNF receptor superfamily member 5.	Interleukin 10.	0.630