27 items (Columba livia) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LPIN2	Lipin 2. (920 aa)
	KDSR	3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (332 aa)
	SQLE	Squalene epoxidase. (572 aa)
	FASN	Fatty acid synthase. (2513 aa)
	G6PC	Glucose-6-phosphatase, catalytic subunit. (358 aa)
	SREBF1	Sterol regulatory element binding transcription factor 1. (1025 aa)
	MSMO1	Methylsterol monooxygenase 1; Belongs to the sterol desaturase family. (297 aa)
	ACACA	Acetyl-CoA carboxylase alpha. (1676 aa)
	MOGAT2	Monoacylglycerol O-acyltransferase 2. (220 aa)
	DGKQ	Diacylglycerol kinase. (845 aa)
	PCK1	Phosphoenolpyruvate carboxykinase 1 (Soluble). (669 aa)
	MTTP	Microsomal triglyceride transfer protein. (893 aa)
	ELOVL6	Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (300 aa)
	NSDHL	NAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family. (346 aa)
	MOGAT1	Monoacylglycerol O-acyltransferase 1. (334 aa)
	JUN	Jun proto-oncogene; Belongs to the bZIP family. (338 aa)
	GPAM	Glycerol-3-phosphate acyltransferase 1, mitochondrial. (796 aa)
	ALB	Albumin. (609 aa)
	CPT1A	Carnitine palmitoyltransferase 1A (Liver), transcript variant X1. (860 aa)
	G6PC2	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (355 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (327 aa)
	ACSL1	Acyl-CoA synthetase long-chain family member 1. (698 aa)
	ESR2	Estrogen receptor 2 (ER beta). (451 aa)
	APOB	Apolipoprotein B. (2608 aa)
	ESR1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (621 aa)
	ELOVL5	Elongation of very long chain fatty acids protein. (279 aa)
	LPIN1	Lipin 1, transcript variant X2. (939 aa)

Your Current Organism:

Columba livia

NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACACA	ELOVL6	A0A2I0LYG6	A0A2I0M927	Acetyl-CoA carboxylase alpha.	Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...]	0.611
ACACA	FASN	A0A2I0LYG6	A0A2I0LMU2	Acetyl-CoA carboxylase alpha.	Fatty acid synthase.	0.967
ACACA	GAPDH	A0A2I0LYG6	A0A2I0MLP3	Acetyl-CoA carboxylase alpha.	Glyceraldehyde-3-phosphate dehydrogenase.	0.410
ACACA	LPIN1	A0A2I0LYG6	A0A2I0MVJ0	Acetyl-CoA carboxylase alpha.	Lipin 1, transcript variant X2.	0.433
ACSL1	CPT1A	A0A2I0MMI8	A0A2I0MI90	Acyl-CoA synthetase long-chain family member 1.	Carnitine palmitoyltransferase 1A (Liver), transcript variant X1.	0.953
ACSL1	FASN	A0A2I0MMI8	A0A2I0LMU2	Acyl-CoA synthetase long-chain family member 1.	Fatty acid synthase.	0.920
ALB	APOB	A0A2I0MH12	A0A2I0MU22	Albumin.	Apolipoprotein B.	0.485
ALB	GAPDH	A0A2I0MH12	A0A2I0MLP3	Albumin.	Glyceraldehyde-3-phosphate dehydrogenase.	0.546
APOB	ALB	A0A2I0MU22	A0A2I0MH12	Apolipoprotein B.	Albumin.	0.485
APOB	FASN	A0A2I0MU22	A0A2I0LMU2	Apolipoprotein B.	Fatty acid synthase.	0.435
APOB	MTTP	A0A2I0MU22	A0A2I0M900	Apolipoprotein B.	Microsomal triglyceride transfer protein.	0.969
CPT1A	ACSL1	A0A2I0MI90	A0A2I0MMI8	Carnitine palmitoyltransferase 1A (Liver), transcript variant X1.	Acyl-CoA synthetase long-chain family member 1.	0.953
CPT1A	FASN	A0A2I0MI90	A0A2I0LMU2	Carnitine palmitoyltransferase 1A (Liver), transcript variant X1.	Fatty acid synthase.	0.422
CPT1A	PCK1	A0A2I0MI90	A0A2I0M656	Carnitine palmitoyltransferase 1A (Liver), transcript variant X1.	Phosphoenolpyruvate carboxykinase 1 (Soluble).	0.469
DGKQ	MOGAT1	A0A2I0M5D1	A0A2I0MBD6	Diacylglycerol kinase.	Monoacylglycerol O-acyltransferase 1.	0.906
DGKQ	MOGAT2	A0A2I0M5D1	A0A2I0M2L2	Diacylglycerol kinase.	Monoacylglycerol O-acyltransferase 2.	0.901
ELOVL5	ELOVL6	A0A2I0MUW5	A0A2I0M927	Elongation of very long chain fatty acids protein.	Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...]	0.944
ELOVL6	ACACA	A0A2I0M927	A0A2I0LYG6	Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...]	Acetyl-CoA carboxylase alpha.	0.611
ELOVL6	ELOVL5	A0A2I0M927	A0A2I0MUW5	Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...]	Elongation of very long chain fatty acids protein.	0.944
ELOVL6	FASN	A0A2I0M927	A0A2I0LMU2	Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...]	Fatty acid synthase.	0.703