STRINGSTRING
HADHA HADHA HMGCL HMGCL HMGCS1 HMGCS1 OXCT1 OXCT1 L2HGDH L2HGDH EHHADH EHHADH ALDH5A1 ALDH5A1 ACSM3 ACSM3 A306_00008415 A306_00008415 A306_00008414 A306_00008414 ECHS1 ECHS1 ABAT ABAT AACS AACS HADH HADH A306_00007703 A306_00007703 ACAT1 ACAT1 HMGCS2 HMGCS2 GAD1 GAD1 GAD2 GAD2 ACAT2 ACAT2 HMGCLL1 HMGCLL1 BDH1 BDH1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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HADHAEnoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (770 aa)
HMGCL3-hydroxymethyl-3-methylglutaryl-CoA lyase, transcript variant X1. (323 aa)
HMGCS13-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (522 aa)
OXCT1Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (542 aa)
L2HGDHL-2-hydroxyglutarate dehydrogenase. (385 aa)
EHHADHEnoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (669 aa)
ALDH5A1Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (405 aa)
ACSM3Acyl-CoA synthetase medium-chain family member 3, transcript variant X1. (579 aa)
A306_00008415Acyl-coenzyme A synthetase ACSM4, mitochondrial. (579 aa)
A306_00008414Acyl-coenzyme A synthetase ACSM4, mitochondrial, transcript variant X1. (580 aa)
ECHS1Enoyl CoA hydratase, short chain, 1, mitochondrial. (144 aa)
ABAT4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (500 aa)
AACSAcetoacetyl-CoA synthetase. (667 aa)
HADHHydroxyacyl-CoA dehydrogenase. (304 aa)
A306_00007703D-beta-hydroxybutyrate dehydrogenase, mitochondrial; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (348 aa)
ACAT1Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (422 aa)
HMGCS23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (403 aa)
GAD1Glutamate decarboxylase 1 (Brain, 67kDa), transcript variant X1. (595 aa)
GAD2Glutamate decarboxylase 2 (Pancreatic islets and brain, 65kDa). (548 aa)
ACAT2Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (340 aa)
HMGCLL13-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1. (304 aa)
BDH1D-beta-hydroxybutyrate dehydrogenase, mitochondrial; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (343 aa)
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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