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ICMT ICMT A306_00013807 A306_00013807 FDPS FDPS ZMPSTE24 ZMPSTE24 HMGCS1 HMGCS1 PCYOX1 PCYOX1 HMGCR HMGCR FNTA FNTA MVK MVK ACAT1 ACAT1 HMGCS2 HMGCS2 A306_00002460 A306_00002460 PDSS1 PDSS1 PDSS2 PDSS2 ACAT2 ACAT2 GGPS1 GGPS1 NUS1 NUS1 DHDDS DHDDS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ICMTProtein-S-isoprenylcysteine O-methyltransferase. (188 aa)
A306_00013807Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding. (305 aa)
FDPSFarnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. (304 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (227 aa)
HMGCS13-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (522 aa)
PCYOX1Prenylcys_lyase domain-containing protein. (364 aa)
HMGCR3-hydroxy-3-methylglutaryl coenzyme A reductase. (882 aa)
FNTAFarnesyltransferase, CAAX box, alpha. (305 aa)
MVKMevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (397 aa)
ACAT1Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (422 aa)
HMGCS23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (403 aa)
A306_00002460Isopentenyl-diphosphate Delta-isomerase 1. (227 aa)
PDSS1Prenyl (Decaprenyl) diphosphate synthase, subunit 1; Belongs to the FPP/GGPP synthase family. (339 aa)
PDSS2Prenyl (Decaprenyl) diphosphate synthase, subunit 2; Belongs to the FPP/GGPP synthase family. (334 aa)
ACAT2Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (340 aa)
GGPS1Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. (299 aa)
NUS1NUS1 dehydrodolichyl diphosphate synthase subunit. (145 aa)
DHDDSAlkyl transferase; Belongs to the UPP synthase family. (333 aa)
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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