100 items (Columba livia) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LMNA	Lamin A/C; Belongs to the intermediate filament family. (524 aa)
	A306_00015030	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (457 aa)
	TUBA4A	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (433 aa)
	A306_00014966	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
	NTRK1	Neurotrophic tyrosine kinase, receptor, type 1. (272 aa)
	IKBKB	Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta. (743 aa)
	GADD45B	Growth arrest and DNA-damage-inducible, beta. (111 aa)
	A306_00013164	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (452 aa)
	LMNB2	Lamin B2; Belongs to the intermediate filament family. (619 aa)
	CTSS	Cathepsin S; Belongs to the peptidase C1 family. (333 aa)
	MCL1	Myeloid cell leukemia 1. (224 aa)
	AIFM1	Apoptosis-inducing factor, mitochondrion-associated, 1. (443 aa)
	BCL2L1	BCL2-like 1. (230 aa)
	ITPR3	Inositol 1,4,5-trisphosphate receptor, type 3. (2664 aa)
	BAK1	BCL2-antagonist/killer 1. (217 aa)
	MAP3K14	Mitogen-activated protein kinase kinase kinase 14. (601 aa)
	A306_00013512	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
	MAP2K2	Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (403 aa)
	PIK3R2	Phosphoinositide-3-kinase, regulatory subunit 2 (Beta). (727 aa)
	CASP10	Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (443 aa)
	A306_00011847	Caspase-8, transcript variant X2; Belongs to the peptidase C14A family. (464 aa)
	A306_00011848	Caspase-8, transcript variant X1; Belongs to the peptidase C14A family. (455 aa)
	CFLAR	CASP8 and FADD-like apoptosis regulator, transcript variant X1; Belongs to the peptidase C14A family. (487 aa)
	A306_00012533	Cathepsin L1-like; Belongs to the peptidase C1 family. (361 aa)
	CTSO	Cathepsin O, transcript variant X1; Belongs to the peptidase C1 family. (268 aa)
	APAF1	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa)
	BIRC5	Baculoviral IAP repeat containing 5. (103 aa)
	PIK3CB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1066 aa)
	PDPK1	3-phosphoinositide dependent protein kinase 1. (524 aa)
	ERN2	Endoplasmic reticulum to nucleus signaling 2. (850 aa)
	CHUK	Conserved helix-loop-helix ubiquitous kinase. (681 aa)
	TUBAL3	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (459 aa)
	MAPK8	Mitogen-activated protein kinase. (427 aa)
	FAS	Fas cell surface death receptor. (399 aa)
	PIK3R3	Phosphoinositide-3-kinase, regulatory subunit 3 (Gamma), transcript variant X1. (731 aa)
	NGF	Nerve growth factor (Beta polypeptide); Belongs to the NGF-beta family. (267 aa)
	NRAS	Neuroblastoma RAS viral (V-ras) oncogene homolog. (123 aa)
	TRADD	TNFRSF1A-associated via death domain. (306 aa)
	ACTB	Actin, beta. (375 aa)
	CTSC	Cathepsin C; Belongs to the peptidase C1 family. (475 aa)
	PIK3R1	Phosphoinositide-3-kinase, regulatory subunit 1 (Alpha), transcript variant X1. (724 aa)
	A306_00009373	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (418 aa)
	PIK3CD	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1046 aa)
	CASP9	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (409 aa)
	DFFB	DNAation factor, 40kDa, beta polypeptide (Caspase-activated DNase). (165 aa)
	DFFA	DNAation factor, 45kDa, alpha polypeptide. (303 aa)
	TRAF1	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (556 aa)
	SPTAN1	Spectrin, alpha, non-erythrocytic 1, transcript variant X1. (2533 aa)
	ENDOG	Endonuclease G. (159 aa)
	DAB2IP	DAB2 interacting protein. (880 aa)
	CAPN2	Calpain 2, (M/II) large subunit; Belongs to the peptidase C2 family. (693 aa)
	PARP1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (971 aa)
	CTSZ	Cathepsin Z; Belongs to the peptidase C1 family. (283 aa)
	LMNB1	Lamin B1; Belongs to the intermediate filament family. (544 aa)
	ERN1	Endoplasmic reticulum to nucleus signaling 1, transcript variant X1. (804 aa)
	MAPK1	Mitogen-activated protein kinase 1, transcript variant X2. (263 aa)
	DIABLO	Diablo, IAP-binding mitochondrial protein. (259 aa)
	NFKB1	Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1. (959 aa)
	CASP6	Caspase 6, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (303 aa)
	ITPR1	Inositol 1,4,5-trisphosphate receptor, type 1. (1897 aa)
	MAPK9	Mitogen-activated protein kinase. (424 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1052 aa)
	JUN	Jun proto-oncogene; Belongs to the bZIP family. (338 aa)
	FASLG	Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family. (295 aa)
	ATM	Non-specific serine/threonine protein kinase. (3056 aa)
	BIRC2	Baculoviral IAP repeat containing 2. (611 aa)
	MAP2K1	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (395 aa)
	BCL2A1	BCL2-related protein A1. (174 aa)
	CTSH	Cathepsin H; Belongs to the peptidase C1 family. (259 aa)
	A306_00005537	Lamin-L(III); Belongs to the intermediate filament family. (427 aa)
	CASP7	Caspase 7, apoptosis-related cysteine peptidase, transcript variant X1; Belongs to the peptidase C14A family. (309 aa)
	CTSL	Cathepsin L; Belongs to the peptidase C1 family. (338 aa)
	GADD45G	Growth arrest and DNA-damage-inducible, gamma. (110 aa)
	PTPN13	Protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase). (2516 aa)
	MAPK10	Mitogen-activated protein kinase. (484 aa)
	A306_00004635	Putative LOC102095613. (416 aa)
	CTSD	Cathepsin D; Belongs to the peptidase A1 family. (367 aa)
	HRAS	Uncharacterized protein. (189 aa)
	FADD	Fas (TNFRSF6)-associated via death domain. (195 aa)
	PIDD1	P53-induced death domain protein 1, transcript variant X1. (895 aa)
	A306_00004030	Baculoviral IAP repeat-containing protein 5.1. (183 aa)
	ATF4	Activating transcription factor 4. (354 aa)
	CSF2RB	Cytokine receptor common subunit beta. (925 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor, type 2. (2638 aa)
	KRAS	Uncharacterized protein. (197 aa)
	BID	BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (191 aa)
	TUBA8	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (381 aa)
	A306_00004478	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
	TNFRSF1A	Tumor necrosis factor receptor superfamily member 1A. (394 aa)
	CASP2	Caspase 2, apoptosis-related cysteine peptidase, transcript variant X1; Belongs to the peptidase C14A family. (426 aa)
	CASP3	Caspase 3, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (282 aa)
	EIF2S1	Eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa. (315 aa)
	NFKBIA	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha. (333 aa)
	FOS	FBJ murine osteosarcoma viral oncogene homolog. (158 aa)
	A306_00002661	Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
	MAP3K5	Mitogen-activated protein kinase kinase kinase 5. (981 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	BCL2	B-cell CLL/lymphoma 2. (138 aa)
	RIPK1	Receptor (TNFRSF)-interacting serine-threonine kinase 1. (685 aa)
	CTSB	Cathepsin B; Belongs to the peptidase C1 family. (340 aa)

Your Current Organism:

Columba livia

NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A306_00002661	A306_00011847	A0A2I0MQ77	A0A2I0LQ88	Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Caspase-8, transcript variant X2; Belongs to the peptidase C14A family.	0.700
A306_00002661	A306_00011848	A0A2I0MQ77	A0A2I0LQ91	Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Caspase-8, transcript variant X1; Belongs to the peptidase C14A family.	0.764
A306_00002661	AIFM1	A0A2I0MQ77	A0A2I0LM74	Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Apoptosis-inducing factor, mitochondrion-associated, 1.	0.549
A306_00002661	AKT3	A0A2I0MQ77	A0A2I0MTK2	Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.476
A306_00002661	APAF1	A0A2I0MQ77	A0A2I0LUL5	Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.999
A306_00002661	BAK1	A0A2I0MQ77	A0A2I0LNN2	Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	BCL2-antagonist/killer 1.	0.976
A306_00002661	BCL2	A0A2I0MQ77	A0A2I0MW17	Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	B-cell CLL/lymphoma 2.	0.879
A306_00002661	BCL2A1	A0A2I0MQ77	A0A2I0MDD6	Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	BCL2-related protein A1.	0.483
A306_00002661	BCL2L1	A0A2I0MQ77	A0A2I0LMZ0	Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	BCL2-like 1.	0.825
A306_00002661	BIRC2	A0A2I0MQ77	A0A2I0MCS5	Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Baculoviral IAP repeat containing 2.	0.459
A306_00002661	CASP10	A0A2I0MQ77	A0A2I0LQ83	Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.503
A306_00002661	CASP2	A0A2I0MQ77	A0A2I0MLS1	Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Caspase 2, apoptosis-related cysteine peptidase, transcript variant X1; Belongs to the peptidase C14A family.	0.759
A306_00002661	CASP3	A0A2I0MQ77	A0A2I0MMP4	Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Caspase 3, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.889
A306_00002661	CASP6	A0A2I0MQ77	A0A2I0M918	Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Caspase 6, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.741
A306_00002661	CASP7	A0A2I0MQ77	A0A2I0MEW3	Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Caspase 7, apoptosis-related cysteine peptidase, transcript variant X1; Belongs to the peptidase C14A family.	0.757
A306_00002661	CASP9	A0A2I0MQ77	A0A2I0M343	Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.998
A306_00002661	CFLAR	A0A2I0MQ77	A0A2I0LQC2	Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	CASP8 and FADD-like apoptosis regulator, transcript variant X1; Belongs to the peptidase C14A family.	0.429
A306_00002661	DIABLO	A0A2I0MQ77	A0A2I0M894	Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Diablo, IAP-binding mitochondrial protein.	0.815
A306_00002661	ENDOG	A0A2I0MQ77	A0A2I0M3W8	Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Endonuclease G.	0.620
A306_00002661	FADD	A0A2I0MQ77	A0A2I0MI45	Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Fas (TNFRSF6)-associated via death domain.	0.482