77 items (Columba livia) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A306_00015030	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (457 aa)
	TUBA4A	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (433 aa)
	A306_00014966	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
	GNAI2	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2. (303 aa)
	A306_00015028	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (273 aa)
	A306_00013164	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (452 aa)
	ADCY6	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1100 aa)
	HTR2B	5-hydroxytryptamine (Serotonin) receptor 2B, G protein-coupled. (463 aa)
	CSNK1D	Casein kinase 1, delta. (385 aa)
	ITPR3	Inositol 1,4,5-trisphosphate receptor, type 3. (2664 aa)
	A306_00013512	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
	MAP2K2	Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (403 aa)
	GNA11	Guanine nucleotide-binding protein subunit alpha-11. (390 aa)
	PLCB2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1210 aa)
	DRD2	Dopamine receptor D2, transcript variant X1; Belongs to the G-protein coupled receptor 1 family. (447 aa)
	SOS2	Uncharacterized protein. (1183 aa)
	DRD1	Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (451 aa)
	A306_00011454	Tubulin beta chain; Belongs to the tubulin family. (299 aa)
	SOS1	Uncharacterized protein. (1323 aa)
	GUCY1B3	Guanylate cyclase 1, soluble, beta 3; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (585 aa)
	PDGFC	Platelet derived growth factor C. (338 aa)
	ADCY3	Adenylate cyclase 3; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (840 aa)
	PRKCB	Protein kinase C, beta; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (634 aa)
	PRKG1	cGMP-dependent protein kinase. (695 aa)
	TUBAL3	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (459 aa)
	A306_00008069	Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (322 aa)
	NRAS	Neuroblastoma RAS viral (V-ras) oncogene homolog. (123 aa)
	PDGFA	Platelet-derived growth factor alpha polypeptide; Belongs to the PDGF/VEGF growth factor family. (150 aa)
	GRM5	Glutamate receptor, metabotropic 5. (1242 aa)
	A306_00009373	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (418 aa)
	SRC	SRC proto-oncogene, non-receptor tyrosine kinase. (320 aa)
	ADCY7	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1072 aa)
	ADCY9	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1346 aa)
	HTR2C	5-hydroxytryptamine (Serotonin) receptor 2C, G protein-coupled, transcript variant X1. (472 aa)
	EGFR	Receptor protein-tyrosine kinase. (1164 aa)
	ADCY1	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1020 aa)
	LPAR1	Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (367 aa)
	GNAS	Guanine nucleotide-binding protein G(S) subunit alpha. (305 aa)
	TUBB1	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
	TJP1	Tight junction protein 1; Belongs to the MAGUK family. (1756 aa)
	PRKCA	Protein kinase C, alpha; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (615 aa)
	GRB2	Growth factor receptor-bound protein 2. (250 aa)
	MAPK1	Mitogen-activated protein kinase 1, transcript variant X2. (263 aa)
	EGF	Epidermal growth factor. (1254 aa)
	PLCB4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1204 aa)
	PLCB1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1243 aa)
	ITPR1	Inositol 1,4,5-trisphosphate receptor, type 1. (1897 aa)
	PDGFRB	Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1137 aa)
	A306_00007654	Guanylate cyclase soluble subunit beta-2-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (782 aa)
	GUCY1A2	Guanylate cyclase 1, soluble, alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (709 aa)
	PDGFD	Platelet derived growth factor D, transcript variant X1. (375 aa)
	MAP2K5	Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (437 aa)
	MAP2K1	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (395 aa)
	PRKACB	Protein kinase, cAMP-dependent, catalytic, beta, transcript variant X1; Belongs to the protein kinase superfamily. (398 aa)
	ADRB1	Adrenoceptor beta 1. (476 aa)
	CDK1	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (302 aa)
	A306_00007955	Guanine nucleotide-binding protein G(Q) subunit alpha. (287 aa)
	MAP3K2	Mitogen-activated protein kinase kinase kinase 2. (624 aa)
	ADCY5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1216 aa)
	PRKG2	cGMP-dependent protein kinase. (777 aa)
	GNAI1	Guanine nucleotide-binding protein G(I) subunit alpha-1. (302 aa)
	HRAS	Uncharacterized protein. (189 aa)
	PDGFB	Platelet-derived growth factor beta polypeptide; Belongs to the PDGF/VEGF growth factor family. (256 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor, type 2. (2638 aa)
	KRAS	Uncharacterized protein. (197 aa)
	TUBA8	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (381 aa)
	A306_00004478	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
	PDGFRA	Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1087 aa)
	GJD2	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (304 aa)
	HTR2A	5-hydroxytryptamine (Serotonin) receptor 2A, G protein-coupled. (471 aa)
	GJA1	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (381 aa)
	GRM1	Glutamate receptor, metabotropic 1, transcript variant X1. (1187 aa)
	TUBB6	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (436 aa)
	ADCY2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1055 aa)
	A306_00001805	Tubulin beta-1 chain, transcript variant X2; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (485 aa)
	A306_00001806	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
	GUCY1A3	Guanylate cyclase soluble subunit alpha-3; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (688 aa)

Your Current Organism:

Columba livia

NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A306_00001805	A306_00004478	A0A2I0MXU3	A0A2I0MKW0	Tubulin beta-1 chain, transcript variant X2; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.866
A306_00001805	A306_00009373	A0A2I0MXU3	A0A2I0M1I4	Tubulin beta-1 chain, transcript variant X2; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.865
A306_00001805	A306_00013164	A0A2I0MXU3	A0A2I0LKI5	Tubulin beta-1 chain, transcript variant X2; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	0.865
A306_00001805	A306_00013512	A0A2I0MXU3	A0A2I0LNR9	Tubulin beta-1 chain, transcript variant X2; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.865
A306_00001805	A306_00014966	A0A2I0MXU3	A0A2I0LHP7	Tubulin beta-1 chain, transcript variant X2; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.865
A306_00001805	A306_00015030	A0A2I0MXU3	A0A2I0LHI4	Tubulin beta-1 chain, transcript variant X2; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	0.866
A306_00001805	GJA1	A0A2I0MXU3	A0A2I0MU91	Tubulin beta-1 chain, transcript variant X2; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.900
A306_00001805	TUBA4A	A0A2I0MXU3	A0A2I0LHP3	Tubulin beta-1 chain, transcript variant X2; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.865
A306_00001805	TUBA8	A0A2I0MXU3	A0A2I0MKV6	Tubulin beta-1 chain, transcript variant X2; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.865
A306_00001805	TUBAL3	A0A2I0MXU3	A0A2I0LX98	Tubulin beta-1 chain, transcript variant X2; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.861
A306_00001806	A306_00004478	A0A2I0MXV7	A0A2I0MKW0	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.865
A306_00001806	A306_00009373	A0A2I0MXV7	A0A2I0M1I4	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.865
A306_00001806	A306_00013164	A0A2I0MXV7	A0A2I0LKI5	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	0.870
A306_00001806	A306_00013512	A0A2I0MXV7	A0A2I0LNR9	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.870
A306_00001806	A306_00014966	A0A2I0MXV7	A0A2I0LHP7	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.870
A306_00001806	A306_00015030	A0A2I0MXV7	A0A2I0LHI4	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	0.865
A306_00001806	GJA1	A0A2I0MXV7	A0A2I0MU91	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.900
A306_00001806	TUBA4A	A0A2I0MXV7	A0A2I0LHP3	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.865
A306_00001806	TUBA8	A0A2I0MXV7	A0A2I0MKV6	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.865
A306_00001806	TUBAL3	A0A2I0MXV7	A0A2I0LX98	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.860