44 items (Columba livia) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TRAF6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa)
	TKFC	Triokinase/FMN cyclase. (424 aa)
	IKBKB	Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta. (743 aa)
	A306_00014013	Mitogen-activated protein kinase. (182 aa)
	DHX58	DEXH (Asp-Glu-X-His) box polypeptide 58. (674 aa)
	CASP10	Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (443 aa)
	A306_00011847	Caspase-8, transcript variant X2; Belongs to the peptidase C14A family. (464 aa)
	A306_00011848	Caspase-8, transcript variant X1; Belongs to the peptidase C14A family. (455 aa)
	TMEM173	Transmembrane protein 173. (384 aa)
	A306_00013079	Interferon alpha-2. (197 aa)
	A306_00010988	E3 ubiquitin/ISG15 ligase TRIM25, transcript variant X1. (410 aa)
	NLRX1	NLR family member X1. (602 aa)
	CHUK	Conserved helix-loop-helix ubiquitous kinase. (681 aa)
	MAPK8	Mitogen-activated protein kinase. (427 aa)
	SIKE1	Suppressor of IKBKE 1. (139 aa)
	IKBKE	Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon. (722 aa)
	TRADD	TNFRSF1A-associated via death domain. (306 aa)
	CYLD	Cylindromatosis (Turban tumor syndrome); Belongs to the peptidase C19 family. (949 aa)
	MAP3K1	Mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase. (1317 aa)
	DDX58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58. (730 aa)
	DDX3X	DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked; Belongs to the DEAD box helicase family. (668 aa)
	TRIM25	E3 ubiquitin/ISG15 ligase TRIM25. (550 aa)
	ATG12	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (160 aa)
	NFKB1	Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1. (959 aa)
	MAPK9	Mitogen-activated protein kinase. (424 aa)
	IL12B	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (315 aa)
	IL-8	Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (103 aa)
	MAPK10	Mitogen-activated protein kinase. (484 aa)
	CXCL8-3	Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (156 aa)
	MAPK12	Mitogen-activated protein kinase. (352 aa)
	A306_00007180	Mitogen-activated protein kinase. (221 aa)
	FADD	Fas (TNFRSF6)-associated via death domain. (195 aa)
	IRF7	Interferon regulatory factor 7. (530 aa)
	IFIH1	Interferon induced with helicase C domain 1. (981 aa)
	TANK	TRAF family member-associated NFKB activator, transcript variant X1. (479 aa)
	TBK1	TANK-binding kinase 1. (729 aa)
	MAVS	Mitochondrial antiviral signaling protein. (632 aa)
	NFKBIA	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha. (333 aa)
	TRAF3	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (567 aa)
	AZI2	5-azacytidine induced 2. (389 aa)
	ATG5	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	RIPK1	Receptor (TNFRSF)-interacting serine-threonine kinase 1. (685 aa)
	A306_00001162	Ubiquitin carboxyl-terminal hydrolase CYLD. (823 aa)
	A306_00014012	Mitogen-activated protein kinase. (365 aa)

Your Current Organism:

Columba livia

NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A306_00001162	A306_00011847	A0A2I0MXZ0	A0A2I0LQ88	Ubiquitin carboxyl-terminal hydrolase CYLD.	Caspase-8, transcript variant X2; Belongs to the peptidase C14A family.	0.914
A306_00001162	A306_00011848	A0A2I0MXZ0	A0A2I0LQ91	Ubiquitin carboxyl-terminal hydrolase CYLD.	Caspase-8, transcript variant X1; Belongs to the peptidase C14A family.	0.914
A306_00001162	CHUK	A0A2I0MXZ0	A0A2I0LX57	Ubiquitin carboxyl-terminal hydrolase CYLD.	Conserved helix-loop-helix ubiquitous kinase.	0.712
A306_00001162	CYLD	A0A2I0MXZ0	A0A2I0M2H6	Ubiquitin carboxyl-terminal hydrolase CYLD.	Cylindromatosis (Turban tumor syndrome); Belongs to the peptidase C19 family.	0.903
A306_00001162	DDX58	A0A2I0MXZ0	A0A2I0M5H9	Ubiquitin carboxyl-terminal hydrolase CYLD.	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58.	0.945
A306_00001162	FADD	A0A2I0MXZ0	A0A2I0MI45	Ubiquitin carboxyl-terminal hydrolase CYLD.	Fas (TNFRSF6)-associated via death domain.	0.600
A306_00001162	IKBKB	A0A2I0MXZ0	A0A2I0LJJ4	Ubiquitin carboxyl-terminal hydrolase CYLD.	Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta.	0.676
A306_00001162	IKBKE	A0A2I0MXZ0	A0A2I0M078	Ubiquitin carboxyl-terminal hydrolase CYLD.	Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon.	0.958
A306_00001162	RIPK1	A0A2I0MXZ0	A0A2I0MXV2	Ubiquitin carboxyl-terminal hydrolase CYLD.	Receptor (TNFRSF)-interacting serine-threonine kinase 1.	0.985
A306_00001162	TBK1	A0A2I0MXZ0	A0A2I0MJ78	Ubiquitin carboxyl-terminal hydrolase CYLD.	TANK-binding kinase 1.	0.600
A306_00001162	TRADD	A0A2I0MXZ0	A0A2I0M095	Ubiquitin carboxyl-terminal hydrolase CYLD.	TNFRSF1A-associated via death domain.	0.771
A306_00001162	TRAF3	A0A2I0MXZ0	A0A2I0MP89	Ubiquitin carboxyl-terminal hydrolase CYLD.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.608
A306_00001162	TRAF6	A0A2I0MXZ0	A0A172PWX2	Ubiquitin carboxyl-terminal hydrolase CYLD.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.883
A306_00007180	A306_00014012	A0A2I0MHJ1	R7VV07	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.466
A306_00007180	MAPK12	A0A2I0MHJ1	A0A2I0MH92	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.477
A306_00010988	DDX58	A0A2I0LT92	A0A2I0M5H9	E3 ubiquitin/ISG15 ligase TRIM25, transcript variant X1.	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58.	0.926
A306_00010988	TRIM25	A0A2I0LT92	A0A2I0M7I4	E3 ubiquitin/ISG15 ligase TRIM25, transcript variant X1.	E3 ubiquitin/ISG15 ligase TRIM25.	0.900
A306_00011847	A306_00001162	A0A2I0LQ88	A0A2I0MXZ0	Caspase-8, transcript variant X2; Belongs to the peptidase C14A family.	Ubiquitin carboxyl-terminal hydrolase CYLD.	0.914
A306_00011847	A306_00011848	A0A2I0LQ88	A0A2I0LQ91	Caspase-8, transcript variant X2; Belongs to the peptidase C14A family.	Caspase-8, transcript variant X1; Belongs to the peptidase C14A family.	0.904
A306_00011847	ATG5	A0A2I0LQ88	A0A2I0MTW3	Caspase-8, transcript variant X2; Belongs to the peptidase C14A family.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.462