STRINGSTRING
A306_00014800 A306_00014800 A306_00000277 A306_00000277 CACNA1S CACNA1S PTK2B PTK2B CAMK2B CAMK2B ADCY6 ADCY6 A306_00014013 A306_00014013 MAP3K3 MAP3K3 ITPR3 ITPR3 MAP2K4 MAP2K4 MAP2K2 MAP2K2 GNA11 GNA11 PLCB2 PLCB2 CDC42 CDC42 PLA2G4A PLA2G4A SOS2 SOS2 PRKCD PRKCD SOS1 SOS1 EGR1 EGR1 GNRH1 GNRH1 ADCY3 ADCY3 PRKCB PRKCB A306_00011314 A306_00011314 MAPK8 MAPK8 NRAS NRAS MAP2K3 MAP2K3 SRC SRC MMP2 MMP2 ADCY7 ADCY7 ADCY9 ADCY9 EGFR EGFR ADCY1 ADCY1 MAP3K1 MAP3K1 GNAS GNAS PRKCA PRKCA MAP2K6 MAP2K6 GRB2 GRB2 MAPK1 MAPK1 PLCB4 PLCB4 PLCB1 PLCB1 CACNA1D CACNA1D ITPR1 ITPR1 MAPK9 MAPK9 CAMK2A CAMK2A A306_00008766 A306_00008766 PLD1 PLD1 JUN JUN A306_00005626 A306_00005626 MAP2K1 MAP2K1 CALML4 CALML4 PRKACB PRKACB CAMK2G CAMK2G A306_00007955 A306_00007955 MAP3K2 MAP3K2 ADCY5 ADCY5 MAPK10 MAPK10 MAPK12 MAPK12 A306_00007180 A306_00007180 HRAS HRAS FSHB FSHB ATF4 ATF4 ITPR2 ITPR2 KRAS KRAS PLA2G4F PLA2G4F A306_00001971 A306_00001971 A306_00001972 A306_00001972 A306_00001970 A306_00001970 A306_00001963 A306_00001963 A306_00001968 A306_00001968 A306_00001966 A306_00001966 A306_00001967 A306_00001967 A306_00002410 A306_00002410 CGA CGA MAP3K4 MAP3K4 ADCY2 ADCY2 A306_00014012 A306_00014012
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A306_00014800Gonadotropin-releasing hormone receptor-like. (415 aa)
A306_00000277Ion_trans domain-containing protein. (139 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1848 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (945 aa)
CAMK2BCalcium/calmodulin-dependent protein kinase II beta. (334 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1100 aa)
A306_00014013Mitogen-activated protein kinase. (182 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3, transcript variant X1. (646 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor, type 3. (2664 aa)
MAP2K4Mitogen-activated protein kinase kinase 4. (725 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (403 aa)
GNA11Guanine nucleotide-binding protein subunit alpha-11. (390 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1210 aa)
CDC42Cell division cycle 42, transcript variant X2. (191 aa)
PLA2G4APhospholipase A2. (749 aa)
SOS2Uncharacterized protein. (1183 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (685 aa)
SOS1Uncharacterized protein. (1323 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (480 aa)
GNRH1Gonadotropin-releasing hormone 1 (Luteinizing-releasing hormone). (157 aa)
ADCY3Adenylate cyclase 3; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (840 aa)
PRKCBProtein kinase C, beta; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (634 aa)
A306_00011314Calmodulin, striated muscle; Belongs to the calmodulin family. (149 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
NRASNeuroblastoma RAS viral (V-ras) oncogene homolog. (123 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (348 aa)
SRCSRC proto-oncogene, non-receptor tyrosine kinase. (320 aa)
MMP2Matrix metallopeptidase 2. (661 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1072 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1346 aa)
EGFRReceptor protein-tyrosine kinase. (1164 aa)
ADCY1Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1020 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase. (1317 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha. (305 aa)
PRKCAProtein kinase C, alpha; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (615 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (316 aa)
GRB2Growth factor receptor-bound protein 2. (250 aa)
MAPK1Mitogen-activated protein kinase 1, transcript variant X2. (263 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1204 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1243 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor, type 1. (1897 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase II alpha, transcript variant X1; Belongs to the protein kinase superfamily. (489 aa)
A306_00008766Calmodulin; Belongs to the calmodulin family. (149 aa)
PLD1Phospholipase. (1075 aa)
JUNJun proto-oncogene; Belongs to the bZIP family. (338 aa)
A306_00005626Gonadotropin-releasing hormone II receptor; Belongs to the G-protein coupled receptor 1 family. (358 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (395 aa)
CALML4Calmodulin-like 4. (153 aa)
PRKACBProtein kinase, cAMP-dependent, catalytic, beta, transcript variant X1; Belongs to the protein kinase superfamily. (398 aa)
CAMK2GCalcium/calmodulin-dependent protein kinase II gamma. (510 aa)
A306_00007955Guanine nucleotide-binding protein G(Q) subunit alpha. (287 aa)
MAP3K2Mitogen-activated protein kinase kinase kinase 2. (624 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1216 aa)
MAPK10Mitogen-activated protein kinase. (484 aa)
MAPK12Mitogen-activated protein kinase. (352 aa)
A306_00007180Mitogen-activated protein kinase. (221 aa)
HRASUncharacterized protein. (189 aa)
FSHBFollicle stimulating hormone, beta polypeptide. (131 aa)
ATF4Activating transcription factor 4. (354 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor, type 2. (2638 aa)
KRASUncharacterized protein. (197 aa)
PLA2G4FPhospholipase A2. (852 aa)
A306_00001971Phospholipase A2. (810 aa)
A306_00001972Phospholipase A2. (844 aa)
A306_00001970Phospholipase A2. (822 aa)
A306_00001963Phospholipase A2. (878 aa)
A306_00001968Phospholipase A2. (838 aa)
A306_00001966Cytosolic phospholipase A2 epsilon. (723 aa)
A306_00001967Phospholipase A2. (837 aa)
A306_00002410Mitogen-activated protein kinase kinase kinase 3. (674 aa)
CGAGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (120 aa)
MAP3K4Mitogen-activated protein kinase kinase kinase 4. (1564 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1055 aa)
A306_00014012Mitogen-activated protein kinase. (365 aa)
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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