STRINGSTRING
WNT6 WNT6 CREB3 CREB3 GNAI2 GNAI2 WNT10A WNT10A TCF7L1 TCF7L1 CAMK2B CAMK2B WNT1 WNT1 ADCY6 ADCY6 ASIP ASIP FZD9 FZD9 FZD2 FZD2 WNT9B WNT9B CREB3L3 CREB3L3 MAP2K2 MAP2K2 PLCB2 PLCB2 FZD7 FZD7 WNT4 WNT4 CTNNB1 CTNNB1 A306_00012717 A306_00012717 WNT7A WNT7A ADCY3 ADCY3 FZD3 FZD3 KITLG KITLG PRKCB PRKCB A306_00011314 A306_00011314 FZD5 FZD5 CREB1 CREB1 WNT8B WNT8B WNT2B WNT2B NRAS NRAS TYR TYR FZD4 FZD4 ADCY7 ADCY7 WNT11 WNT11 DVL1 DVL1 ADCY9 ADCY9 CREBBP CREBBP ADCY1 ADCY1 GNAS GNAS PRKCA PRKCA MAPK1 MAPK1 FZD10 FZD10 LEF1 LEF1 PLCB4 PLCB4 PLCB1 PLCB1 WNT5A WNT5A CAMK2A CAMK2A WNT8A WNT8A TCF7 TCF7 A306_00008766 A306_00008766 A306_00007629 A306_00007629 MAP2K1 MAP2K1 CALML4 CALML4 PRKACB PRKACB TCF7L2 TCF7L2 CAMK2G CAMK2G A306_00007955 A306_00007955 ADCY5 ADCY5 GNAI1 GNAI1 HRAS HRAS WNT16 WNT16 EP300 EP300 WNT7B WNT7B CREB3L2 CREB3L2 KRAS KRAS WNT5B WNT5B A306_00003658 A306_00003658 GSK3B GSK3B KIT KIT CREB3L1 CREB3L1 WNT3A WNT3A WNT9A WNT9A EDNRB EDNRB DCT DCT FZD6 FZD6 ADCY2 ADCY2 EDN1 EDN1 WNT3 WNT3 MITF MITF MC1R MC1R Tyrp1 Tyrp1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (301 aa)
CREB3cAMP responsive element binding protein 3. (438 aa)
GNAI2Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2. (303 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (364 aa)
TCF7L1Transcription factor 7-like 1 (T-cell specific, HMG-box). (364 aa)
CAMK2BCalcium/calmodulin-dependent protein kinase II beta. (334 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (414 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1100 aa)
ASIPAgouti signaling protein. (126 aa)
FZD9Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (486 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (630 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (333 aa)
CREB3L3cAMP responsive element binding protein 3-like 3. (395 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (403 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1210 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (516 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
CTNNB1Catenin (Cadherin-associated protein), beta 1, 88kDa. (814 aa)
A306_00012717Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (297 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (376 aa)
ADCY3Adenylate cyclase 3; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (840 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
KITLGKIT ligand. (234 aa)
PRKCBProtein kinase C, beta; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (634 aa)
A306_00011314Calmodulin, striated muscle; Belongs to the calmodulin family. (149 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (611 aa)
CREB1cAMP responsive element binding protein 1. (327 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (377 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (321 aa)
NRASNeuroblastoma RAS viral (V-ras) oncogene homolog. (123 aa)
TYRTyrosinase. (528 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (433 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1072 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
DVL1Dishevelled segment polarity protein 1. (561 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1346 aa)
CREBBPCREB binding protein. (2195 aa)
ADCY1Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1020 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha. (305 aa)
PRKCAProtein kinase C, alpha; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (615 aa)
MAPK1Mitogen-activated protein kinase 1, transcript variant X2. (263 aa)
FZD10Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (541 aa)
LEF1Lymphoid enhancer-binding factor 1. (360 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1204 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1243 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase II alpha, transcript variant X1; Belongs to the protein kinase superfamily. (489 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
TCF7Transcription factor 7 (T-cell specific, HMG-box), transcript variant X1. (340 aa)
A306_00008766Calmodulin; Belongs to the calmodulin family. (149 aa)
A306_00007629Endothelin B receptor; Belongs to the G-protein coupled receptor 1 family. (467 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (395 aa)
CALML4Calmodulin-like 4. (153 aa)
PRKACBProtein kinase, cAMP-dependent, catalytic, beta, transcript variant X1; Belongs to the protein kinase superfamily. (398 aa)
TCF7L2Transcription factor 7-like 2 (T-cell specific, HMG-box). (224 aa)
CAMK2GCalcium/calmodulin-dependent protein kinase II gamma. (510 aa)
A306_00007955Guanine nucleotide-binding protein G(Q) subunit alpha. (287 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1216 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1. (302 aa)
HRASUncharacterized protein. (189 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (193 aa)
EP300E1A binding protein p300. (2044 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
CREB3L2cAMP responsive element binding protein 3-like 2. (456 aa)
KRASUncharacterized protein. (197 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (329 aa)
A306_00003658Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (348 aa)
GSK3BGlycogen synthase kinase 3 beta, transcript variant X1; Belongs to the protein kinase superfamily. (433 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (963 aa)
CREB3L1cAMP responsive element binding protein 3-like 1. (458 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (377 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (316 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (353 aa)
DCTDopachrome tautomerase. (499 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (670 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1055 aa)
EDN1Endothelin 1. (231 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
MITFMicrophthalmia-associated transcription factor, transcript variant X1. (468 aa)
MC1RMelanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. (313 aa)
Tyrp1Tyrosinase-related protein 1. (536 aa)
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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