(10 nodes) Immunity, and Toll-like receptor binding network (Callipepla squamata)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ASZ78_004936	CUE domain-containing protein. (253 aa)
	ASZ78_014329	Protein kinase domain-containing protein. (680 aa)
	ASZ78_015469	TIR domain-containing protein. (310 aa)
	ASZ78_013118	TIR domain-containing protein; Belongs to the Toll-like receptor family. (896 aa)
	ASZ78_009185	Protein kinase domain-containing protein. (443 aa)
	ASZ78_010603	TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (736 aa)
	ASZ78_016219	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (299 aa)
	ASZ78_005609	TIR domain-containing protein; Belongs to the Toll-like receptor family. (818 aa)
	ASZ78_015256	TIR domain-containing protein; Belongs to the Toll-like receptor family. (890 aa)
	ASZ78_009641	TIR domain-containing protein; Belongs to the glycosyltransferase 29 family. (1107 aa)

Your Current Organism:

Callipepla squamata

NCBI taxonomy Id: 9009
Other names: C. squamata, scaled quail

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASZ78_004936	ASZ78_005609	A0A226MFE7	A0A226NKC0	CUE domain-containing protein.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.935
ASZ78_004936	ASZ78_009185	A0A226MFE7	A0A226MTG9	CUE domain-containing protein.	Protein kinase domain-containing protein.	0.971
ASZ78_004936	ASZ78_009641	A0A226MFE7	A0A226NN17	CUE domain-containing protein.	TIR domain-containing protein; Belongs to the glycosyltransferase 29 family.	0.650
ASZ78_004936	ASZ78_013118	A0A226MFE7	A0A226MN15	CUE domain-containing protein.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.453
ASZ78_004936	ASZ78_014329	A0A226MFE7	A0A226MKE9	CUE domain-containing protein.	Protein kinase domain-containing protein.	0.948
ASZ78_004936	ASZ78_015256	A0A226MFE7	A0A226NKT0	CUE domain-containing protein.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.552
ASZ78_004936	ASZ78_015469	A0A226MFE7	A0A226ML31	CUE domain-containing protein.	TIR domain-containing protein.	0.948
ASZ78_004936	ASZ78_016219	A0A226MFE7	A0A226N889	CUE domain-containing protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.963
ASZ78_005609	ASZ78_004936	A0A226NKC0	A0A226MFE7	TIR domain-containing protein; Belongs to the Toll-like receptor family.	CUE domain-containing protein.	0.935
ASZ78_005609	ASZ78_009185	A0A226NKC0	A0A226MTG9	TIR domain-containing protein; Belongs to the Toll-like receptor family.	Protein kinase domain-containing protein.	0.609
ASZ78_005609	ASZ78_009641	A0A226NKC0	A0A226NN17	TIR domain-containing protein; Belongs to the Toll-like receptor family.	TIR domain-containing protein; Belongs to the glycosyltransferase 29 family.	0.926
ASZ78_005609	ASZ78_010603	A0A226NKC0	A0A226MTT9	TIR domain-containing protein; Belongs to the Toll-like receptor family.	TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines.	0.698
ASZ78_005609	ASZ78_013118	A0A226NKC0	A0A226MN15	TIR domain-containing protein; Belongs to the Toll-like receptor family.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.573
ASZ78_005609	ASZ78_015256	A0A226NKC0	A0A226NKT0	TIR domain-containing protein; Belongs to the Toll-like receptor family.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.737
ASZ78_005609	ASZ78_015469	A0A226NKC0	A0A226ML31	TIR domain-containing protein; Belongs to the Toll-like receptor family.	TIR domain-containing protein.	0.989
ASZ78_005609	ASZ78_016219	A0A226NKC0	A0A226N889	TIR domain-containing protein; Belongs to the Toll-like receptor family.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.992
ASZ78_009185	ASZ78_004936	A0A226MTG9	A0A226MFE7	Protein kinase domain-containing protein.	CUE domain-containing protein.	0.971
ASZ78_009185	ASZ78_005609	A0A226MTG9	A0A226NKC0	Protein kinase domain-containing protein.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.609
ASZ78_009185	ASZ78_009641	A0A226MTG9	A0A226NN17	Protein kinase domain-containing protein.	TIR domain-containing protein; Belongs to the glycosyltransferase 29 family.	0.979
ASZ78_009185	ASZ78_010603	A0A226MTG9	A0A226MTT9	Protein kinase domain-containing protein.	TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines.	0.945