(25 nodes) Mixed, incl. NOTCH3 Activation and Transmission of Signal to the Nucleus, and Mastermind-like 1-3 network (Callipepla squamata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ASZ78_005248	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (334 aa)
	ASZ78_004530	Uncharacterized protein. (651 aa)
	ASZ78_003201	Uncharacterized protein. (1893 aa)
	ASZ78_007121	Uncharacterized protein. (257 aa)
	ASZ78_012132	Ncstrn_small domain-containing protein. (720 aa)
	ASZ78_015436	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (351 aa)
	ASZ78_015437	Uncharacterized protein. (136 aa)
	ASZ78_000925	Uncharacterized protein. (1011 aa)
	ASZ78_000158	Uncharacterized protein. (2143 aa)
	ASZ78_000157	Uncharacterized protein. (263 aa)
	ASZ78_003815	Uncharacterized protein. (309 aa)
	ASZ78_004782	MamL-1 domain-containing protein. (1051 aa)
	ASZ78_013577	Uncharacterized protein. (364 aa)
	ASZ78_008444	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (691 aa)
	ASZ78_013575	Uncharacterized protein. (208 aa)
	ASZ78_010377	Uncharacterized protein. (228 aa)
	ASZ78_010376	Uncharacterized protein. (380 aa)
	ASZ78_006864	Uncharacterized protein. (557 aa)
	ASZ78_001921	Uncharacterized protein. (481 aa)
	ASZ78_001038	Uncharacterized protein. (467 aa)
	ASZ78_017111	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (708 aa)
	ASZ78_014134	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1083 aa)
	ASZ78_012989	Uncharacterized protein. (488 aa)
	ASZ78_013078	Uncharacterized protein. (256 aa)
	ASZ78_005698	Uncharacterized protein. (2538 aa)

Your Current Organism:

Callipepla squamata

NCBI taxonomy Id: 9009
Other names: C. squamata, scaled quail

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASZ78_000157	ASZ78_000925	A0A226MS23	A0A226MPK2	Uncharacterized protein.	Uncharacterized protein.	0.413
ASZ78_000157	ASZ78_001038	A0A226MS23	A0A226N7B5	Uncharacterized protein.	Uncharacterized protein.	0.982
ASZ78_000157	ASZ78_001921	A0A226MS23	A0A226N6Z6	Uncharacterized protein.	Uncharacterized protein.	0.931
ASZ78_000157	ASZ78_003201	A0A226MS23	A0A226MF19	Uncharacterized protein.	Uncharacterized protein.	0.413
ASZ78_000157	ASZ78_004530	A0A226MS23	A0A226MDU4	Uncharacterized protein.	Uncharacterized protein.	0.967
ASZ78_000157	ASZ78_004782	A0A226MS23	A0A226MVR7	Uncharacterized protein.	MamL-1 domain-containing protein.	0.702
ASZ78_000157	ASZ78_005248	A0A226MS23	A0A226MCQ1	Uncharacterized protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.672
ASZ78_000157	ASZ78_005698	A0A226MS23	A0A226NHG9	Uncharacterized protein.	Uncharacterized protein.	0.923
ASZ78_000157	ASZ78_006864	A0A226MS23	A0A226N6P5	Uncharacterized protein.	Uncharacterized protein.	0.684
ASZ78_000157	ASZ78_007121	A0A226MS23	A0A226MKH9	Uncharacterized protein.	Uncharacterized protein.	0.904
ASZ78_000157	ASZ78_008444	A0A226MS23	A0A226N1G3	Uncharacterized protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.959
ASZ78_000157	ASZ78_010376	A0A226MS23	A0A226N2L4	Uncharacterized protein.	Uncharacterized protein.	0.617
ASZ78_000157	ASZ78_010377	A0A226MS23	A0A226N2L1	Uncharacterized protein.	Uncharacterized protein.	0.805
ASZ78_000157	ASZ78_012132	A0A226MS23	A0A226MKQ6	Uncharacterized protein.	Ncstrn_small domain-containing protein.	0.925
ASZ78_000157	ASZ78_012989	A0A226MS23	A0A226NFL3	Uncharacterized protein.	Uncharacterized protein.	0.945
ASZ78_000157	ASZ78_013078	A0A226MS23	A0A226NH06	Uncharacterized protein.	Uncharacterized protein.	0.901
ASZ78_000157	ASZ78_014134	A0A226MS23	A0A226ND11	Uncharacterized protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.972
ASZ78_000157	ASZ78_015436	A0A226MS23	A0A226MN02	Uncharacterized protein.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.926
ASZ78_000157	ASZ78_015437	A0A226MS23	A0A226MNL6	Uncharacterized protein.	Uncharacterized protein.	0.650
ASZ78_000157	ASZ78_017111	A0A226MS23	A0A226NCV3	Uncharacterized protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.786