(60 nodes) Epithelial to mesenchymal transition network (Callipepla squamata)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ASZ78_009670	DUF3715 domain-containing protein. (1636 aa)
	ASZ78_009624	ZP domain-containing protein. (643 aa)
	ASZ78_009521	Olfactomedin-like domain-containing protein. (485 aa)
	ASZ78_014580	BTB domain-containing protein. (575 aa)
	ASZ78_014365	HMG box domain-containing protein. (330 aa)
	ASZ78_008658	T-box_assoc domain-containing protein. (593 aa)
	ASZ78_008666	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (425 aa)
	ASZ78_016662	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (376 aa)
	ASZ78_015305	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1023 aa)
	ASZ78_006596	Uncharacterized protein. (371 aa)
	ASZ78_014691	Homeobox domain-containing protein. (265 aa)
	ASZ78_015913	BTB domain-containing protein. (578 aa)
	ASZ78_010889	Uncharacterized protein; Belongs to the heparin-binding growth factors family. (190 aa)
	ASZ78_013539	Homeobox domain-containing protein. (149 aa)
	ASZ78_003552	Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
	ASZ78_011585	Uncharacterized protein. (713 aa)
	ASZ78_011901	EF-hand domain-containing protein. (114 aa)
	ASZ78_015059	FERM domain-containing protein. (751 aa)
	ASZ78_014120	TGF_BETA_2 domain-containing protein. (392 aa)
	ASZ78_016631	Uncharacterized protein. (276 aa)
	ASZ78_016630	Uncharacterized protein. (1030 aa)
	ASZ78_009790	Uncharacterized protein. (216 aa)
	ASZ78_009770	Uncharacterized protein. (71 aa)
	ASZ78_001801	Uncharacterized protein; Belongs to the MAGUK family. (1887 aa)
	ASZ78_009768	TBX domain-containing protein. (594 aa)
	ASZ78_006580	Uncharacterized protein; Belongs to the DEAD box helicase family. (583 aa)
	ASZ78_000133	Ig-like domain-containing protein. (99 aa)
	ASZ78_003132	Uncharacterized protein. (213 aa)
	ASZ78_006974	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (269 aa)
	ASZ78_005433	Uncharacterized protein. (433 aa)
	ASZ78_005431	FAM83 domain-containing protein. (527 aa)
	ASZ78_010805	Fibroblast growth factor receptor. (837 aa)
	ASZ78_013792	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (214 aa)
	ASZ78_014403	Uncharacterized protein; Belongs to the DEAD box helicase family. (685 aa)
	ASZ78_012312	Uncharacterized protein. (205 aa)
	ASZ78_013028	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (316 aa)
	ASZ78_001874	LisH domain-containing protein. (609 aa)
	ASZ78_009162	Uncharacterized protein. (552 aa)
	ASZ78_004801	LisH domain-containing protein. (1026 aa)
	ASZ78_005984	Noggin; Belongs to the noggin family. (223 aa)
	ASZ78_013035	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (776 aa)
	ASZ78_007776	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1405 aa)
	ASZ78_005987	Uncharacterized protein. (134 aa)
	ASZ78_008243	HMG box domain-containing protein. (496 aa)
	ASZ78_000836	Uncharacterized protein. (163 aa)
	ASZ78_014307	TBX domain-containing protein. (732 aa)
	ASZ78_013758	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (113 aa)
	ASZ78_001340	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
	ASZ78_013748	Uncharacterized protein. (268 aa)
	ASZ78_014553	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (542 aa)
	ASZ78_002298	TGF_BETA_2 domain-containing protein. (199 aa)
	ASZ78_017091	Uncharacterized protein. (256 aa)
	ASZ78_013240	ZP domain-containing protein. (837 aa)
	ASZ78_002142	Uncharacterized protein. (785 aa)
	ASZ78_004211	Mothers against decapentaplegic homolog. (479 aa)
	ASZ78_012112	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (410 aa)
	ASZ78_009264	Olfactomedin-like domain-containing protein. (478 aa)
	ASZ78_008318	Uncharacterized protein. (88 aa)
	ASZ78_012545	Helicase C-terminal domain-containing protein. (201 aa)
	ASZ78_012083	Uncharacterized protein. (145 aa)

Your Current Organism:

Callipepla squamata

NCBI taxonomy Id: 9009
Other names: C. squamata, scaled quail

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASZ78_000133	ASZ78_001340	A0A226NAD2	A0A226MKX2	Ig-like domain-containing protein.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.924
ASZ78_000133	ASZ78_010889	A0A226NAD2	A0A226NIE4	Ig-like domain-containing protein.	Uncharacterized protein; Belongs to the heparin-binding growth factors family.	0.894
ASZ78_000133	ASZ78_013758	A0A226NAD2	A0A226MMR5	Ig-like domain-containing protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.827
ASZ78_000836	ASZ78_015913	A0A226MPV3	A0A226NIM6	Uncharacterized protein.	BTB domain-containing protein.	0.571
ASZ78_001340	ASZ78_000133	A0A226MKX2	A0A226NAD2	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	Ig-like domain-containing protein.	0.924
ASZ78_001340	ASZ78_010805	A0A226MKX2	A0A226N5G5	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	Fibroblast growth factor receptor.	0.995
ASZ78_001340	ASZ78_010889	A0A226MKX2	A0A226NIE4	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	Uncharacterized protein; Belongs to the heparin-binding growth factors family.	0.570
ASZ78_001801	ASZ78_015059	A0A226NBY7	A0A226NE48	Uncharacterized protein; Belongs to the MAGUK family.	FERM domain-containing protein.	0.670
ASZ78_001874	ASZ78_006580	A0A226MWZ2	A0A226NBH1	LisH domain-containing protein.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.478
ASZ78_001874	ASZ78_012545	A0A226MWZ2	A0A226M841	LisH domain-containing protein.	Helicase C-terminal domain-containing protein.	0.478
ASZ78_001874	ASZ78_014403	A0A226MWZ2	A0A226MZZ8	LisH domain-containing protein.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.462
ASZ78_001874	ASZ78_014580	A0A226MWZ2	A0A226NLJ7	LisH domain-containing protein.	BTB domain-containing protein.	0.613
ASZ78_001874	ASZ78_015305	A0A226MWZ2	A0A226NKY5	LisH domain-containing protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.891
ASZ78_002298	ASZ78_003552	A0A226MIE7	A0A226NHF3	TGF_BETA_2 domain-containing protein.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.949
ASZ78_002298	ASZ78_004211	A0A226MIE7	A0A226MF11	TGF_BETA_2 domain-containing protein.	Mothers against decapentaplegic homolog.	0.631
ASZ78_002298	ASZ78_005984	A0A226MIE7	A0A226MTL6	TGF_BETA_2 domain-containing protein.	Noggin; Belongs to the noggin family.	0.604
ASZ78_002298	ASZ78_008243	A0A226MIE7	A0A226MR05	TGF_BETA_2 domain-containing protein.	HMG box domain-containing protein.	0.529
ASZ78_002298	ASZ78_008666	A0A226MIE7	A0A226NL83	TGF_BETA_2 domain-containing protein.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.999
ASZ78_002298	ASZ78_009624	A0A226MIE7	A0A226NP00	TGF_BETA_2 domain-containing protein.	ZP domain-containing protein.	0.505
ASZ78_002298	ASZ78_012112	A0A226MIE7	A0A226ME75	TGF_BETA_2 domain-containing protein.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.976