(108 nodes) Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds network (Callipepla squamata)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ASZ78_014229	Amidohydro-rel domain-containing protein. (480 aa)
	ASZ78_013882	Uncharacterized protein. (469 aa)
	ASZ78_011895	Hist_deacetyl domain-containing protein. (426 aa)
	ASZ78_000640	Uncharacterized protein. (155 aa)
	ASZ78_006656	Uncharacterized protein. (365 aa)
	ASZ78_015448	Fibrinogen C-terminal domain-containing protein. (282 aa)
	ASZ78_007289	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (411 aa)
	ASZ78_016988	Hist_deacetyl domain-containing protein. (362 aa)
	ASZ78_008381	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins; Belongs to the polypeptide deformylase family. (183 aa)
	ASZ78_010382	Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (453 aa)
	ASZ78_008399	A to I editase domain-containing protein. (546 aa)
	ASZ78_008396	Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (369 aa)
	ASZ78_007366	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (428 aa)
	ASZ78_009973	Uncharacterized protein; Belongs to the arginase family. (307 aa)
	ASZ78_008693	Deacetylase sirtuin-type domain-containing protein. (317 aa)
	ASZ78_008740	CN hydrolase domain-containing protein. (397 aa)
	ASZ78_005149	Uncharacterized protein. (325 aa)
	ASZ78_009968	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (191 aa)
	ASZ78_013277	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
	ASZ78_000306	HIT domain-containing protein. (126 aa)
	ASZ78_013738	Uncharacterized protein. (210 aa)
	ASZ78_006515	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (482 aa)
	ASZ78_008681	HIT domain-containing protein. (174 aa)
	ASZ78_016928	Uncharacterized protein. (399 aa)
	ASZ78_013785	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (236 aa)
	ASZ78_002951	DUF4201 domain-containing protein. (405 aa)
	ASZ78_013241	Uncharacterized protein. (193 aa)
	ASZ78_005796	Hist_deacetyl domain-containing protein. (484 aa)
	ASZ78_013414	Uncharacterized protein. (499 aa)
	ASZ78_006714	DRMBL domain-containing protein. (946 aa)
	ASZ78_010236	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1101 aa)
	ASZ78_006316	Deacetylase sirtuin-type domain-containing protein. (359 aa)
	ASZ78_000729	MGS domain-containing protein. (593 aa)
	ASZ78_006319	Uncharacterized protein. (549 aa)
	ASZ78_010429	CN hydrolase domain-containing protein. (294 aa)
	ASZ78_005906	Uncharacterized protein. (515 aa)
	ASZ78_004458	Uncharacterized protein. (137 aa)
	ASZ78_013671	Deacetylase sirtuin-type domain-containing protein. (399 aa)
	AFMID	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. (234 aa)
	ASZ78_001976	Lactamase_B domain-containing protein. (277 aa)
	ASZ78_007236	AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (767 aa)
	ASZ78_012398	Amidohydro-rel domain-containing protein. (435 aa)
	ASZ78_004988	Uncharacterized protein. (665 aa)
	ASZ78_004989	Uncharacterized protein. (740 aa)
	ASZ78_004983	Uncharacterized protein. (469 aa)
	ASZ78_004475	Uncharacterized protein. (86 aa)
	ASZ78_010087	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. (750 aa)
	ASZ78_010079	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (263 aa)
	ASZ78_004476	Uncharacterized protein. (130 aa)
	ASZ78_007801	N-acetylglucosamine-6-phosphate deacetylase; Belongs to the metallo-dependent hydrolases superfamily. NagA family. (338 aa)
	ASZ78_011677	Amidohydro-rel domain-containing protein. (647 aa)
	ASZ78_005849	Uncharacterized protein. (381 aa)
	ASZ78_006931	M20_dimer domain-containing protein. (413 aa)
	ASZ78_006550	CMP/dCMP-type deaminase domain-containing protein. (190 aa)
	ASZ78_014844	Uncharacterized protein. (90 aa)
	ASZ78_009298	Uncharacterized protein. (193 aa)
	ASZ78_000563	Amidase domain-containing protein. (481 aa)
	ASZ78_000565	Hist_deacetyl domain-containing protein. (374 aa)
	ASZ78_005385	Amidohydro-rel domain-containing protein. (467 aa)
	ASZ78_013764	DRBM domain-containing protein. (120 aa)
	ASZ78_008794	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (985 aa)
	ASZ78_003850	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (276 aa)
	ASZ78_013760	A to I editase domain-containing protein. (332 aa)
	ASZ78_004554	DRMBL domain-containing protein. (375 aa)
	ASZ78_007943	Fibrinogen C-terminal domain-containing protein. (223 aa)
	ASZ78_011429	Amidohydro-rel domain-containing protein. (683 aa)
	ASZ78_007472	ANK_REP_REGION domain-containing protein. (533 aa)
	ASZ78_002119	CMP/dCMP-type deaminase domain-containing protein. (202 aa)
	ASZ78_007945	Fibrinogen C-terminal domain-containing protein. (214 aa)
	ASZ78_007947	Uncharacterized protein. (313 aa)
	ASZ78_007948	Fibrinogen C-terminal domain-containing protein. (292 aa)
	ASZ78_007939	Fibrinogen C-terminal domain-containing protein. (278 aa)
	ASZ78_005111	Amidohydro-rel domain-containing protein. (737 aa)
	ASZ78_012745	CN hydrolase domain-containing protein. (521 aa)
	ASZ78_001636	CMP/dCMP-type deaminase domain-containing protein. (222 aa)
	ASZ78_009173	ANK_REP_REGION domain-containing protein. (93 aa)
	ASZ78_006124	A_deaminase domain-containing protein. (343 aa)
	ASZ78_002869	Uncharacterized protein. (319 aa)
	ASZ78_015387	Uncharacterized protein. (1049 aa)
	ASZ78_005585	Uncharacterized protein. (337 aa)
	ASZ78_010032	CN hydrolase domain-containing protein. (370 aa)
	ASZ78_002968	Uncharacterized protein. (83 aa)
	ASZ78_004847	Uncharacterized protein. (278 aa)
	ASZ78_002965	Amidohydro-rel domain-containing protein. (514 aa)
	ASZ78_000027	CN hydrolase domain-containing protein. (293 aa)
	ASZ78_012290	Uncharacterized protein. (325 aa)
	ASZ78_001824	Uncharacterized protein. (602 aa)
	ASZ78_012231	HIT domain-containing protein. (183 aa)
	ASZ78_003026	Uncharacterized protein. (252 aa)
	ASZ78_007879	Deacetylase sirtuin-type domain-containing protein. (140 aa)
	ASZ78_001892	Deacetylase sirtuin-type domain-containing protein. (593 aa)
	ASZ78_002557	Neutral ceramidase. (625 aa)
	ASZ78_002559	Ceramidse_alk_C domain-containing protein. (72 aa)
	ASZ78_001411	Fibrinogen C-terminal domain-containing protein. (260 aa)
	ASZ78_004919	Neutral ceramidase. (357 aa)
	ASZ78_012755	Uncharacterized protein. (441 aa)
	ASZ78_014046	Deacetylase sirtuin-type domain-containing protein. (198 aa)
	ASZ78_000483	Uncharacterized protein. (500 aa)
	ASZ78_008655	PAW domain-containing protein. (651 aa)
	ASZ78_000390	AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (774 aa)
	SIRT5	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (296 aa)
	ASZ78_015873	AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (733 aa)
	ASZ78_017055	Uncharacterized protein. (531 aa)
	ASZ78_010271	Uncharacterized protein; Belongs to the arginase family. (208 aa)
	ASZ78_015806	M20_dimer domain-containing protein. (517 aa)
	ASZ78_010031	CN hydrolase domain-containing protein. (509 aa)
	ASZ78_010033	CN hydrolase domain-containing protein. (139 aa)
	ASZ78_000482	Uncharacterized protein. (983 aa)

Your Current Organism:

Callipepla squamata

NCBI taxonomy Id: 9009
Other names: C. squamata, scaled quail

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFMID	ASZ78_000027	A0A226N0I3	A0A226MET8	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	CN hydrolase domain-containing protein.	0.492
AFMID	ASZ78_008740	A0A226N0I3	A0A226NAQ8	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	CN hydrolase domain-containing protein.	0.492
AFMID	ASZ78_010031	A0A226N0I3	A0A226NM26	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	CN hydrolase domain-containing protein.	0.492
AFMID	ASZ78_010032	A0A226N0I3	A0A226NLJ5	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	CN hydrolase domain-containing protein.	0.492
AFMID	ASZ78_010033	A0A226N0I3	A0A226NLT5	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	CN hydrolase domain-containing protein.	0.492
AFMID	ASZ78_010087	A0A226N0I3	A0A226MW73	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.	0.477
AFMID	ASZ78_010429	A0A226N0I3	A0A226N241	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	CN hydrolase domain-containing protein.	0.492
AFMID	ASZ78_012745	A0A226N0I3	A0A226MIW5	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	CN hydrolase domain-containing protein.	0.492
ASZ78_000027	AFMID	A0A226MET8	A0A226N0I3	CN hydrolase domain-containing protein.	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	0.492
ASZ78_000027	ASZ78_000482	A0A226MET8	A0A226NLJ6	CN hydrolase domain-containing protein.	Uncharacterized protein.	0.600
ASZ78_000027	ASZ78_000483	A0A226MET8	A0A226NLD3	CN hydrolase domain-containing protein.	Uncharacterized protein.	0.600
ASZ78_000027	ASZ78_000563	A0A226MET8	A0A226MPH1	CN hydrolase domain-containing protein.	Amidase domain-containing protein.	0.600
ASZ78_000027	ASZ78_000640	A0A226MET8	A0A226NF58	CN hydrolase domain-containing protein.	Uncharacterized protein.	0.653
ASZ78_000027	ASZ78_001892	A0A226MET8	A0A226MDM0	CN hydrolase domain-containing protein.	Deacetylase sirtuin-type domain-containing protein.	0.470
ASZ78_000027	ASZ78_002965	A0A226MET8	A0A226MEZ5	CN hydrolase domain-containing protein.	Amidohydro-rel domain-containing protein.	0.612
ASZ78_000027	ASZ78_002968	A0A226MET8	A0A226MF94	CN hydrolase domain-containing protein.	Uncharacterized protein.	0.612
ASZ78_000027	ASZ78_003026	A0A226MET8	A0A226MDU9	CN hydrolase domain-containing protein.	Uncharacterized protein.	0.475
ASZ78_000027	ASZ78_005111	A0A226MET8	A0A226MJW4	CN hydrolase domain-containing protein.	Amidohydro-rel domain-containing protein.	0.612
ASZ78_000027	ASZ78_005385	A0A226MET8	A0A226MNT1	CN hydrolase domain-containing protein.	Amidohydro-rel domain-containing protein.	0.612
ASZ78_000027	ASZ78_005585	A0A226MET8	A0A226MFL5	CN hydrolase domain-containing protein.	Uncharacterized protein.	0.504