(18 nodes) Negative regulation of epithelial cell differentiation network (Callipepla squamata)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Your Input:
	ASZ78_002334	Uncharacterized protein. (157 aa)
	ASZ78_013143	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (683 aa)
	ASZ78_008804	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (516 aa)
	ASZ78_014307	TBX domain-containing protein. (732 aa)
	ASZ78_017030	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (229 aa)
	ASZ78_010568	Uncharacterized protein. (689 aa)
	ASZ78_008243	HMG box domain-containing protein. (496 aa)
	ASZ78_009376	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (380 aa)
	ASZ78_009455	Uncharacterized protein. (264 aa)
	ASZ78_010789	Homeobox domain-containing protein. (259 aa)
	ASZ78_006399	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (796 aa)
	ASZ78_014985	Uncharacterized protein. (404 aa)
	ASZ78_009768	TBX domain-containing protein. (594 aa)
	ASZ78_009770	Uncharacterized protein. (71 aa)
	ASZ78_017111	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (708 aa)
	ASZ78_014134	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1083 aa)
	ASZ78_015461	Uncharacterized protein. (456 aa)
	ASZ78_002714	Uncharacterized protein. (655 aa)

Your Current Organism:

Callipepla squamata

NCBI taxonomy Id: 9009
Other names: C. squamata, scaled quail

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASZ78_002334	ASZ78_014134	A0A226MDL8	A0A226ND11	Uncharacterized protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.450
ASZ78_002334	ASZ78_017111	A0A226MDL8	A0A226NCV3	Uncharacterized protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.474
ASZ78_002714	ASZ78_008243	A0A226NEJ1	A0A226MR05	Uncharacterized protein.	HMG box domain-containing protein.	0.705
ASZ78_002714	ASZ78_010568	A0A226NEJ1	A0A226MQL1	Uncharacterized protein.	Uncharacterized protein.	0.474
ASZ78_002714	ASZ78_013143	A0A226NEJ1	A0A226MLC3	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.439
ASZ78_002714	ASZ78_014134	A0A226NEJ1	A0A226ND11	Uncharacterized protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.427
ASZ78_002714	ASZ78_017030	A0A226NEJ1	A0A226MP27	Uncharacterized protein.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.589
ASZ78_002714	ASZ78_017111	A0A226NEJ1	A0A226NCV3	Uncharacterized protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.505
ASZ78_008243	ASZ78_002714	A0A226MR05	A0A226NEJ1	HMG box domain-containing protein.	Uncharacterized protein.	0.705
ASZ78_008243	ASZ78_014134	A0A226MR05	A0A226ND11	HMG box domain-containing protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.559
ASZ78_009455	ASZ78_010568	A0A226N559	A0A226MQL1	Uncharacterized protein.	Uncharacterized protein.	0.430
ASZ78_010568	ASZ78_002714	A0A226MQL1	A0A226NEJ1	Uncharacterized protein.	Uncharacterized protein.	0.474
ASZ78_010568	ASZ78_009455	A0A226MQL1	A0A226N559	Uncharacterized protein.	Uncharacterized protein.	0.430
ASZ78_010568	ASZ78_014134	A0A226MQL1	A0A226ND11	Uncharacterized protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.547
ASZ78_010568	ASZ78_017111	A0A226MQL1	A0A226NCV3	Uncharacterized protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.495
ASZ78_013143	ASZ78_002714	A0A226MLC3	A0A226NEJ1	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.439
ASZ78_014134	ASZ78_002334	A0A226ND11	A0A226MDL8	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.450
ASZ78_014134	ASZ78_002714	A0A226ND11	A0A226NEJ1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.427
ASZ78_014134	ASZ78_008243	A0A226ND11	A0A226MR05	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	HMG box domain-containing protein.	0.559
ASZ78_014134	ASZ78_010568	A0A226ND11	A0A226MQL1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.547