(32 nodes) Regulation of chemokine production network (Callipepla squamata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ASZ78_005674	Uncharacterized protein. (1865 aa)
	ASZ78_004352	G_PROTEIN_RECEP_F1_2 domain-containing protein. (156 aa)
	ASZ78_016846	Uncharacterized protein. (132 aa)
	ASZ78_013345	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (510 aa)
	ASZ78_010858	Uncharacterized protein. (162 aa)
	ASZ78_012896	Uncharacterized protein. (339 aa)
	ASZ78_007126	Uncharacterized protein. (309 aa)
	ASZ78_015469	TIR domain-containing protein. (310 aa)
	ASZ78_013118	TIR domain-containing protein; Belongs to the Toll-like receptor family. (896 aa)
	ASZ78_008298	Uncharacterized protein. (280 aa)
	ASZ78_003627	C1q domain-containing protein. (270 aa)
	ASZ78_007643	MFS domain-containing protein. (429 aa)
	ASZ78_007652	Interleukin-18. (196 aa)
	ASZ78_004480	Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (340 aa)
	ASZ78_004799	Ig-like domain-containing protein. (405 aa)
	ASZ78_004809	Thyroglobulin type-1 domain-containing protein. (304 aa)
	ASZ78_010074	Uncharacterized protein. (407 aa)
	ASZ78_007057	CARD_2 domain-containing protein. (586 aa)
	ASZ78_011168	Uncharacterized protein. (536 aa)
	ASZ78_010747	Uncharacterized protein. (198 aa)
	ASZ78_005908	SEFIR domain-containing protein. (856 aa)
	ASZ78_013186	Uncharacterized protein. (827 aa)
	ASZ78_014750	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (189 aa)
	ASZ78_009961	Uncharacterized protein. (321 aa)
	ASZ78_009991	Uncharacterized protein. (973 aa)
	ASZ78_004872	Uncharacterized protein. (434 aa)
	ASZ78_008328	Uncharacterized protein. (1098 aa)
	ASZ78_009642	Uncharacterized protein. (626 aa)
	ASZ78_005293	Uncharacterized protein. (490 aa)
	ASZ78_005070	Protein kinase domain-containing protein. (215 aa)
	ASZ78_008203	Uncharacterized protein. (535 aa)
	ASZ78_005689	CARD domain-containing protein. (530 aa)

Your Current Organism:

Callipepla squamata

NCBI taxonomy Id: 9009
Other names: C. squamata, scaled quail

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASZ78_003627	ASZ78_008298	A0A226MU44	A0A226MNA1	C1q domain-containing protein.	Uncharacterized protein.	0.722
ASZ78_004352	ASZ78_004872	A0A226M550	A0A226NPV5	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Uncharacterized protein.	0.628
ASZ78_004352	ASZ78_005908	A0A226M550	A0A226N2G2	G_PROTEIN_RECEP_F1_2 domain-containing protein.	SEFIR domain-containing protein.	0.513
ASZ78_004352	ASZ78_009991	A0A226M550	A0A226NA81	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Uncharacterized protein.	0.496
ASZ78_004799	ASZ78_004809	A0A226MWF0	A0A226MWF7	Ig-like domain-containing protein.	Thyroglobulin type-1 domain-containing protein.	0.581
ASZ78_004799	ASZ78_008298	A0A226MWF0	A0A226MNA1	Ig-like domain-containing protein.	Uncharacterized protein.	0.664
ASZ78_004799	ASZ78_009991	A0A226MWF0	A0A226NA81	Ig-like domain-containing protein.	Uncharacterized protein.	0.732
ASZ78_004799	ASZ78_010747	A0A226MWF0	A0A226N1U6	Ig-like domain-containing protein.	Uncharacterized protein.	0.562
ASZ78_004799	ASZ78_013118	A0A226MWF0	A0A226MN15	Ig-like domain-containing protein.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.402
ASZ78_004809	ASZ78_004799	A0A226MWF7	A0A226MWF0	Thyroglobulin type-1 domain-containing protein.	Ig-like domain-containing protein.	0.581
ASZ78_004809	ASZ78_007057	A0A226MWF7	A0A226MY38	Thyroglobulin type-1 domain-containing protein.	CARD_2 domain-containing protein.	0.433
ASZ78_004809	ASZ78_008328	A0A226MWF7	A0A226NBQ2	Thyroglobulin type-1 domain-containing protein.	Uncharacterized protein.	0.433
ASZ78_004809	ASZ78_013345	A0A226MWF7	A0A226MET9	Thyroglobulin type-1 domain-containing protein.	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	0.436
ASZ78_004872	ASZ78_004352	A0A226NPV5	A0A226M550	Uncharacterized protein.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.628
ASZ78_004872	ASZ78_005070	A0A226NPV5	A0A226NCX4	Uncharacterized protein.	Protein kinase domain-containing protein.	0.636
ASZ78_004872	ASZ78_005689	A0A226NPV5	A0A226NHI2	Uncharacterized protein.	CARD domain-containing protein.	0.930
ASZ78_004872	ASZ78_007057	A0A226NPV5	A0A226MY38	Uncharacterized protein.	CARD_2 domain-containing protein.	0.648
ASZ78_004872	ASZ78_015469	A0A226NPV5	A0A226ML31	Uncharacterized protein.	TIR domain-containing protein.	0.561
ASZ78_005070	ASZ78_004872	A0A226NCX4	A0A226NPV5	Protein kinase domain-containing protein.	Uncharacterized protein.	0.636
ASZ78_005070	ASZ78_007057	A0A226NCX4	A0A226MY38	Protein kinase domain-containing protein.	CARD_2 domain-containing protein.	0.596