(59 nodes) Organ growth network (Callipepla squamata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ASZ78_017039	Uncharacterized protein. (217 aa)
	ASZ78_002929	Uncharacterized protein. (307 aa)
	ASZ78_013340	Uncharacterized protein. (452 aa)
	ASZ78_009102	Uncharacterized protein. (423 aa)
	ASZ78_002814	Uncharacterized protein. (218 aa)
	ASZ78_003350	Annexin. (657 aa)
	ASZ78_002298	TGF_BETA_2 domain-containing protein. (199 aa)
	ASZ78_016695	Uncharacterized protein. (371 aa)
	ASZ78_004819	Protein kinase domain-containing protein. (154 aa)
	ASZ78_004820	Protein kinase domain-containing protein. (76 aa)
	ASZ78_015638	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (390 aa)
	ASZ78_011428	Uncharacterized protein. (845 aa)
	ASZ78_001130	DAN domain-containing protein. (269 aa)
	ASZ78_000233	Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (859 aa)
	ASZ78_008243	HMG box domain-containing protein. (496 aa)
	ASZ78_016438	ZnMc domain-containing protein. (486 aa)
	ASZ78_013296	Homeobox domain-containing protein. (292 aa)
	ASZ78_005881	Annexin. (343 aa)
	ASZ78_012411	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (573 aa)
	ASZ78_015567	Mothers against decapentaplegic homolog. (438 aa)
	ASZ78_000526	Uncharacterized protein. (287 aa)
	ASZ78_012258	DUF4749 domain-containing protein. (198 aa)
	ASZ78_008666	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (425 aa)
	ASZ78_012259	Uncharacterized protein. (172 aa)
	ASZ78_015246	Homeobox domain-containing protein. (370 aa)
	ASZ78_006003	BH4_2 domain-containing protein. (226 aa)
	ASZ78_010889	Uncharacterized protein; Belongs to the heparin-binding growth factors family. (190 aa)
	ASZ78_014235	Uncharacterized protein. (187 aa)
	ASZ78_005715	Uncharacterized protein. (589 aa)
	ASZ78_013890	Uncharacterized protein. (1061 aa)
	ASZ78_011598	Uncharacterized protein. (866 aa)
	ASZ78_012476	Uncharacterized protein. (863 aa)
	ASZ78_017111	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (708 aa)
	ASZ78_006558	Cyclic nucleotide-binding domain-containing protein. (345 aa)
	ASZ78_000226	PIP49_C domain-containing protein. (429 aa)
	ASZ78_001682	Uncharacterized protein. (401 aa)
	ASZ78_002895	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (425 aa)
	ASZ78_008989	NR LBD domain-containing protein. (265 aa)
	ASZ78_000353	WD_REPEATS_REGION domain-containing protein. (638 aa)
	ASZ78_006389	Uncharacterized protein. (144 aa)
	ASZ78_006478	Uncharacterized protein. (683 aa)
	ASZ78_008040	BHLH domain-containing protein. (78 aa)
	ASZ78_001025	Uncharacterized protein. (480 aa)
	ASZ78_013784	Uncharacterized protein. (352 aa)
	ASZ78_006170	G_PROTEIN_RECEP_F1_2 domain-containing protein. (467 aa)
	ASZ78_016927	RFX-type winged-helix domain-containing protein. (1843 aa)
	ASZ78_010747	Uncharacterized protein. (198 aa)
	ASZ78_013501	Tox-GHH domain-containing protein. (1853 aa)
	ASZ78_013503	Teneurin N-terminal domain-containing protein. (119 aa)
	ASZ78_013502	Teneurin N-terminal domain-containing protein. (120 aa)
	ASZ78_011063	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (465 aa)
	ASZ78_004810	Annexin. (705 aa)
	ASZ78_004771	Uncharacterized protein. (1050 aa)
	ASZ78_013437	Uncharacterized protein. (166 aa)
	ASZ78_013745	Uncharacterized protein. (493 aa)
	ASZ78_004328	Uncharacterized protein. (267 aa)
	ASZ78_016693	Uncharacterized protein. (826 aa)
	ASZ78_007242	Uncharacterized protein. (216 aa)
	ASZ78_011480	Homeobox domain-containing protein. (98 aa)

Your Current Organism:

Callipepla squamata

NCBI taxonomy Id: 9009
Other names: C. squamata, scaled quail

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASZ78_000233	ASZ78_006478	A0A226MQF8	A0A226N5Y7	Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.	Uncharacterized protein.	0.504
ASZ78_002298	ASZ78_008243	A0A226MIE7	A0A226MR05	TGF_BETA_2 domain-containing protein.	HMG box domain-containing protein.	0.529
ASZ78_002298	ASZ78_008666	A0A226MIE7	A0A226NL83	TGF_BETA_2 domain-containing protein.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.999
ASZ78_002298	ASZ78_012411	A0A226MIE7	A0A226MSU1	TGF_BETA_2 domain-containing protein.	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	0.988
ASZ78_002298	ASZ78_015567	A0A226MIE7	A0A226MT25	TGF_BETA_2 domain-containing protein.	Mothers against decapentaplegic homolog.	0.444
ASZ78_002298	ASZ78_017111	A0A226MIE7	A0A226NCV3	TGF_BETA_2 domain-containing protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.495
ASZ78_002895	ASZ78_008243	A0A226N909	A0A226MR05	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	HMG box domain-containing protein.	0.736
ASZ78_002895	ASZ78_010889	A0A226N909	A0A226NIE4	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Uncharacterized protein; Belongs to the heparin-binding growth factors family.	0.868
ASZ78_002895	ASZ78_013296	A0A226N909	A0A226MRR8	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Homeobox domain-containing protein.	0.459
ASZ78_002929	ASZ78_004771	A0A226MDA2	A0A226MV19	Uncharacterized protein.	Uncharacterized protein.	0.854
ASZ78_002929	ASZ78_016693	A0A226MDA2	A0A226MCQ3	Uncharacterized protein.	Uncharacterized protein.	0.842
ASZ78_002929	ASZ78_016695	A0A226MDA2	A0A226MJ63	Uncharacterized protein.	Uncharacterized protein.	0.857
ASZ78_003350	ASZ78_005881	A0A226MG95	A0A226MST5	Annexin.	Annexin.	0.649
ASZ78_004328	ASZ78_004771	A0A226MCE0	A0A226MV19	Uncharacterized protein.	Uncharacterized protein.	0.726
ASZ78_004328	ASZ78_016693	A0A226MCE0	A0A226MCQ3	Uncharacterized protein.	Uncharacterized protein.	0.706
ASZ78_004328	ASZ78_016695	A0A226MCE0	A0A226MJ63	Uncharacterized protein.	Uncharacterized protein.	0.620
ASZ78_004771	ASZ78_002929	A0A226MV19	A0A226MDA2	Uncharacterized protein.	Uncharacterized protein.	0.854
ASZ78_004771	ASZ78_004328	A0A226MV19	A0A226MCE0	Uncharacterized protein.	Uncharacterized protein.	0.726
ASZ78_004771	ASZ78_009102	A0A226MV19	A0A226MDM8	Uncharacterized protein.	Uncharacterized protein.	0.543
ASZ78_004810	ASZ78_005881	A0A226MVZ5	A0A226MST5	Annexin.	Annexin.	0.649