(62 nodes) Cellular ketone metabolic process network (Callipepla squamata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ASZ78_014288	PKS_ER domain-containing protein. (331 aa)
	ASZ78_009602	Aminotran_1_2 domain-containing protein. (453 aa)
	ASZ78_002197	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (1526 aa)
	ASZ78_005878	PH domain-containing protein. (574 aa)
	ASZ78_013728	Aminotran_1_2 domain-containing protein. (477 aa)
	ASZ78_002297	Uncharacterized protein. (100 aa)
	ASZ78_002215	Lactamase_B domain-containing protein. (330 aa)
	ASZ78_002214	Lactamase_B domain-containing protein. (282 aa)
	ASZ78_008970	Uncharacterized protein. (413 aa)
	ASZ78_002535	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (355 aa)
	ASZ78_004157	Pyr_redox_2 domain-containing protein. (396 aa)
	ASZ78_010001	Uncharacterized protein. (333 aa)
	COQ5	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (290 aa)
	ASZ78_008386	Uncharacterized protein. (308 aa)
	ASZ78_007604	Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (180 aa)
	ASZ78_003212	Uncharacterized protein. (416 aa)
	ASZ78_010214	Uncharacterized protein. (142 aa)
	AFMID	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. (234 aa)
	ASZ78_000773	Triosephosphate isomerase. (248 aa)
	ASZ78_004987	DJ-1_PfpI domain-containing protein. (189 aa)
	ASZ78_016866	G_PROTEIN_RECEP_F1_2 domain-containing protein. (230 aa)
	ASZ78_016865	G_PROTEIN_RECEP_F1_2 domain-containing protein. (232 aa)
	ASZ78_009080	Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (267 aa)
	ASZ78_010464	Uncharacterized protein; Belongs to the cytochrome P450 family. (508 aa)
	ASZ78_006416	Uncharacterized protein. (153 aa)
	ASZ78_007026	VKc domain-containing protein. (186 aa)
	ASZ78_010171	Uncharacterized protein. (219 aa)
	ASZ78_002367	Polyketide_cyc domain-containing protein. (222 aa)
	ASZ78_016399	Aspartate aminotransferase. (423 aa)
	ASZ78_016410	Uncharacterized protein. (389 aa)
	ASZ78_000074	Uncharacterized protein; Belongs to the FPP/GGPP synthase family. (426 aa)
	ASZ78_003948	Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family. (496 aa)
	ASZ78_015435	Uncharacterized protein. (563 aa)
	ASZ78_006253	Uncharacterized protein. (237 aa)
	ASZ78_006250	Aminotran_1_2 domain-containing protein. (153 aa)
	ASZ78_014062	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (309 aa)
	COQ2	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (335 aa)
	ASZ78_014195	3-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)). (255 aa)
	ASZ78_002874	Uncharacterized protein. (302 aa)
	ASZ78_000099	S5A_REDUCTASE domain-containing protein. (232 aa)
	ASZ78_004034	Polyketide_cyc domain-containing protein. (225 aa)
	ASZ78_000109	Uncharacterized protein. (183 aa)
	ASZ78_014106	NmrA domain-containing protein. (175 aa)
	ASZ78_014777	Uncharacterized protein. (171 aa)
	ASZ78_005919	Uncharacterized protein. (409 aa)
	ASZ78_002463	Uncharacterized protein. (180 aa)
	ASZ78_003588	Uncharacterized protein. (227 aa)
	ASZ78_010238	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (301 aa)
	ASZ78_009031	Uncharacterized protein. (62 aa)
	COQ4	Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. (214 aa)
	ASZ78_011309	Lactamase_B domain-containing protein. (318 aa)
	ASZ78_003520	FAD_binding_3 domain-containing protein. (359 aa)
	ASZ78_006005	Uncharacterized protein. (246 aa)
	ASZ78_010042	Aldedh domain-containing protein. (103 aa)
	ASZ78_006316	Deacetylase sirtuin-type domain-containing protein. (359 aa)
	ASZ78_014272	Uncharacterized protein. (238 aa)
	ASZ78_010215	Uncharacterized protein. (127 aa)
	ASZ78_001331	Methyltransf_11 domain-containing protein. (197 aa)
	ASZ78_003867	Uncharacterized protein; Belongs to the cytochrome P450 family. (266 aa)
	ASZ78_010041	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (289 aa)
	ASZ78_010797	Uncharacterized protein. (400 aa)
	ASZ78_002261	Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (717 aa)

Your Current Organism:

Callipepla squamata

NCBI taxonomy Id: 9009
Other names: C. squamata, scaled quail

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFMID	ASZ78_000109	A0A226N0I3	A0A226MD09	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	Uncharacterized protein.	0.475
AFMID	ASZ78_002874	A0A226N0I3	A0A226MGT3	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	Uncharacterized protein.	0.500
AFMID	ASZ78_003212	A0A226N0I3	A0A226NEN2	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	Uncharacterized protein.	0.960
AFMID	ASZ78_003520	A0A226N0I3	A0A226NHE3	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	FAD_binding_3 domain-containing protein.	0.572
AFMID	ASZ78_003588	A0A226N0I3	A0A226MC04	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	Uncharacterized protein.	0.475
AFMID	ASZ78_005878	A0A226N0I3	A0A226NMY0	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	PH domain-containing protein.	0.961
AFMID	ASZ78_006250	A0A226N0I3	A0A226MJM8	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	Aminotran_1_2 domain-containing protein.	0.937
AFMID	ASZ78_007604	A0A226N0I3	A0A226NE20	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.	0.500
AFMID	ASZ78_009602	A0A226N0I3	A0A226NMT4	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	Aminotran_1_2 domain-containing protein.	0.935
AFMID	ASZ78_010214	A0A226N0I3	A0A226N1W0	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	Uncharacterized protein.	0.943
AFMID	ASZ78_010215	A0A226N0I3	A0A226N2J5	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	Uncharacterized protein.	0.943
AFMID	ASZ78_010797	A0A226N0I3	A0A226N5Z1	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	Uncharacterized protein.	0.941
AFMID	ASZ78_013728	A0A226N0I3	A0A226N700	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	Aminotran_1_2 domain-containing protein.	0.937
AFMID	ASZ78_014106	A0A226N0I3	A0A226MCW4	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	NmrA domain-containing protein.	0.475
AFMID	ASZ78_014777	A0A226N0I3	A0A226MCH6	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	Uncharacterized protein.	0.475
AFMID	COQ5	A0A226N0I3	A0A226NAS5	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).	0.557
ASZ78_000074	ASZ78_001331	A0A226MNV5	A0A226N4S8	Uncharacterized protein; Belongs to the FPP/GGPP synthase family.	Methyltransf_11 domain-containing protein.	0.603
ASZ78_000074	ASZ78_002297	A0A226MNV5	A0A226NNA2	Uncharacterized protein; Belongs to the FPP/GGPP synthase family.	Uncharacterized protein.	0.541
ASZ78_000074	ASZ78_003520	A0A226MNV5	A0A226NHE3	Uncharacterized protein; Belongs to the FPP/GGPP synthase family.	FAD_binding_3 domain-containing protein.	0.738
ASZ78_000074	ASZ78_004987	A0A226MNV5	A0A226MXD4	Uncharacterized protein; Belongs to the FPP/GGPP synthase family.	DJ-1_PfpI domain-containing protein.	0.624