(61 nodes) Regulation of fat cell differentiation network (Callipepla squamata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ASZ78_006727	DIX domain-containing protein. (573 aa)
	ASZ78_004876	Uncharacterized protein. (363 aa)
	ASZ78_002167	UDENN FLCN/SMCR8-type domain-containing protein. (564 aa)
	ASZ78_015247	Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa)
	ASZ78_004707	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (357 aa)
	ASZ78_006793	EGF-like domain-containing protein. (97 aa)
	ASZ78_006794	WIF domain-containing protein. (189 aa)
	ASZ78_015837	HMG box domain-containing protein. (608 aa)
	ASZ78_010264	Uncharacterized protein. (110 aa)
	ASZ78_014096	Uncharacterized protein. (376 aa)
	ASZ78_014231	Uncharacterized protein. (992 aa)
	ASZ78_011944	C3H1-type domain-containing protein. (681 aa)
	ASZ78_004012	PKS_ER domain-containing protein. (363 aa)
	ASZ78_008540	BSD domain-containing protein. (312 aa)
	ASZ78_005057	Uncharacterized protein. (396 aa)
	ASZ78_016626	BZIP domain-containing protein. (142 aa)
	ASZ78_004957	Uncharacterized protein. (379 aa)
	ASZ78_014134	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1083 aa)
	PPARG-2	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (414 aa)
	ASZ78_004959	SH3 domain-containing protein. (270 aa)
	ASZ78_004955	Uncharacterized protein. (1325 aa)
	ASZ78_008328	Uncharacterized protein. (1098 aa)
	ASZ78_006561	Uncharacterized protein. (804 aa)
	ASZ78_008768	ZnMc domain-containing protein. (487 aa)
	ASZ78_014985	Uncharacterized protein. (404 aa)
	ASZ78_008780	Uncharacterized protein. (247 aa)
	ASZ78_007006	Ig-like domain-containing protein. (249 aa)
	ASZ78_004975	Uncharacterized protein. (546 aa)
	ASZ78_005944	Uncharacterized protein. (346 aa)
	ASZ78_003696	Uncharacterized protein. (162 aa)
	ASZ78_001682	Uncharacterized protein. (401 aa)
	ASZ78_008987	Uncharacterized protein. (495 aa)
	ASZ78_006857	Endo/exonuclease/phosphatase domain-containing protein. (365 aa)
	ASZ78_009464	Uncharacterized protein. (189 aa)
	ASZ78_009461	BTB domain-containing protein. (389 aa)
	ASZ78_013430	Uncharacterized protein. (398 aa)
	ASZ78_006316	Deacetylase sirtuin-type domain-containing protein. (359 aa)
	ASZ78_016142	Lactamase_B domain-containing protein. (461 aa)
	ASZ78_007447	Uncharacterized protein. (277 aa)
	ASZ78_012615	Uncharacterized protein. (1089 aa)
	ASZ78_012616	Uncharacterized protein. (217 aa)
	ASZ78_002647	Uncharacterized protein. (603 aa)
	ASZ78_003627	C1q domain-containing protein. (270 aa)
	ASZ78_016850	C2H2-type domain-containing protein. (411 aa)
	ASZ78_007837	Uncharacterized protein. (272 aa)
	ASZ78_005880	Uncharacterized protein. (478 aa)
	ASZ78_004279	G_PROTEIN_RECEP_F1_2 domain-containing protein. (468 aa)
	ASZ78_013596	Uncharacterized protein. (122 aa)
	ASZ78_013599	Uncharacterized protein. (100 aa)
	ASZ78_013756	Uncharacterized protein. (569 aa)
	ASZ78_010685	Fibronectin type-III domain-containing protein. (200 aa)
	ASZ78_000286	BTP domain-containing protein. (312 aa)
	ASZ78_017087	CCAAT/enhancer-binding protein. (279 aa)
	ASZ78_005305	G_PROTEIN_RECEP_F1_2 domain-containing protein. (229 aa)
	ASZ78_006726	RGS domain-containing protein. (342 aa)
	ASZ78_000026	Uncharacterized protein. (446 aa)
	ASZ78_007879	Deacetylase sirtuin-type domain-containing protein. (140 aa)
	ASZ78_001892	Deacetylase sirtuin-type domain-containing protein. (593 aa)
	ASZ78_008670	Uncharacterized protein. (122 aa)
	ASZ78_013745	Uncharacterized protein. (493 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (183 aa)

Your Current Organism:

Callipepla squamata

NCBI taxonomy Id: 9009
Other names: C. squamata, scaled quail

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASZ78_000286	ASZ78_013430	A0A226MHS6	A0A226N3F9	BTP domain-containing protein.	Uncharacterized protein.	0.711
ASZ78_001682	ASZ78_013596	A0A226N995	A0A226MPJ7	Uncharacterized protein.	Uncharacterized protein.	0.757
ASZ78_001682	ASZ78_013599	A0A226N995	A0A226MNX1	Uncharacterized protein.	Uncharacterized protein.	0.757
ASZ78_001892	ASZ78_003627	A0A226MDM0	A0A226MU44	Deacetylase sirtuin-type domain-containing protein.	C1q domain-containing protein.	0.461
ASZ78_001892	ASZ78_005944	A0A226MDM0	A0A226N9X6	Deacetylase sirtuin-type domain-containing protein.	Uncharacterized protein.	0.521
ASZ78_001892	ASZ78_006316	A0A226MDM0	A0A226N2B5	Deacetylase sirtuin-type domain-containing protein.	Deacetylase sirtuin-type domain-containing protein.	0.924
ASZ78_001892	ASZ78_007837	A0A226MDM0	A0A226MSU0	Deacetylase sirtuin-type domain-containing protein.	Uncharacterized protein.	0.478
ASZ78_001892	ASZ78_007879	A0A226MDM0	A0A226MDM9	Deacetylase sirtuin-type domain-containing protein.	Deacetylase sirtuin-type domain-containing protein.	0.888
ASZ78_001892	PPARG	A0A226MDM0	A0A226MAC1	Deacetylase sirtuin-type domain-containing protein.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.899
ASZ78_001892	PPARG-2	A0A226MDM0	A0A226NCS6	Deacetylase sirtuin-type domain-containing protein.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.899
ASZ78_003627	ASZ78_001892	A0A226MU44	A0A226MDM0	C1q domain-containing protein.	Deacetylase sirtuin-type domain-containing protein.	0.461
ASZ78_003627	ASZ78_003696	A0A226MU44	A0A226N9S5	C1q domain-containing protein.	Uncharacterized protein.	0.560
ASZ78_003627	ASZ78_017087	A0A226MU44	A0A226MH09	C1q domain-containing protein.	CCAAT/enhancer-binding protein.	0.745
ASZ78_003627	PPARG	A0A226MU44	A0A226MAC1	C1q domain-containing protein.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.646
ASZ78_003627	PPARG-2	A0A226MU44	A0A226NCS6	C1q domain-containing protein.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.646
ASZ78_003696	ASZ78_003627	A0A226N9S5	A0A226MU44	Uncharacterized protein.	C1q domain-containing protein.	0.560
ASZ78_004955	ASZ78_004957	A0A226NCF5	A0A226ND33	Uncharacterized protein.	Uncharacterized protein.	0.830
ASZ78_004955	ASZ78_004959	A0A226NCF5	A0A226NCH1	Uncharacterized protein.	SH3 domain-containing protein.	0.890
ASZ78_004957	ASZ78_004955	A0A226ND33	A0A226NCF5	Uncharacterized protein.	Uncharacterized protein.	0.830
ASZ78_004957	ASZ78_004959	A0A226ND33	A0A226NCH1	Uncharacterized protein.	SH3 domain-containing protein.	0.907