(80 nodes) Positive regulation of angiogenesis network (Callipepla squamata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ASZ78_008097	G_PROTEIN_RECEP_F1_2 domain-containing protein. (364 aa)
	ASZ78_014107	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (370 aa)
	ASZ78_008196	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (436 aa)
	ASZ78_003866	Uncharacterized protein. (276 aa)
	ASZ78_016641	SAM domain-containing protein. (196 aa)
	ASZ78_011226	Uncharacterized protein. (59 aa)
	ASZ78_001892	Deacetylase sirtuin-type domain-containing protein. (593 aa)
	ASZ78_011225	SOAR domain-containing protein. (457 aa)
	ASZ78_006150	Uncharacterized protein. (171 aa)
	ASZ78_005022	Uncharacterized protein. (391 aa)
	ASZ78_001705	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1220 aa)
	ASZ78_013721	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1313 aa)
	ASZ78_012087	Integrin beta; Belongs to the integrin beta chain family. (722 aa)
	ASZ78_014060	Uncharacterized protein. (176 aa)
	ASZ78_014090	Uncharacterized protein. (342 aa)
	ASZ78_014087	RING-type domain-containing protein. (1564 aa)
	ASZ78_005115	EMI domain-containing protein. (380 aa)
	ASZ78_005114	C1q domain-containing protein. (166 aa)
	ASZ78_002851	Uncharacterized protein. (759 aa)
	ASZ78_001175	Uncharacterized protein. (502 aa)
	ASZ78_003887	Uncharacterized protein. (283 aa)
	ASZ78_001340	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
	ASZ78_000732	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. (128 aa)
	ASZ78_011722	Uncharacterized protein; Belongs to the cytochrome P450 family. (517 aa)
	ASZ78_008790	Uncharacterized protein. (752 aa)
	ASZ78_008791	Ras-GEF domain-containing protein. (238 aa)
	ASZ78_013758	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (113 aa)
	ASZ78_013118	TIR domain-containing protein; Belongs to the Toll-like receptor family. (896 aa)
	ASZ78_008804	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (516 aa)
	ASZ78_014677	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (632 aa)
	ASZ78_013359	Uncharacterized protein. (695 aa)
	ASZ78_010566	Uncharacterized protein. (291 aa)
	ASZ78_015567	Mothers against decapentaplegic homolog. (438 aa)
	ASZ78_012592	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (470 aa)
	ASZ78_010596	Uncharacterized protein. (134 aa)
	ASZ78_006773	Uncharacterized protein. (1125 aa)
	ASZ78_001492	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (420 aa)
	ASZ78_012641	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (152 aa)
	ASZ78_012640	G_PROTEIN_RECEP_F1_2 domain-containing protein. (156 aa)
	ASZ78_000989	JmjC domain-containing protein. (261 aa)
	ASZ78_000754	Uncharacterized protein. (649 aa)
	ASZ78_005245	Integrin beta; Belongs to the integrin beta chain family. (795 aa)
	ASZ78_006316	Deacetylase sirtuin-type domain-containing protein. (359 aa)
	ASZ78_008149	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (186 aa)
	ASZ78_014801	Uncharacterized protein. (170 aa)
	ASZ78_008036	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (283 aa)
	ASZ78_006877	Uncharacterized protein. (93 aa)
	ASZ78_006875	PH domain-containing protein. (511 aa)
	ASZ78_009016	Uncharacterized protein. (729 aa)
	ASZ78_003652	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (143 aa)
	ASZ78_012778	Uncharacterized protein. (466 aa)
	ASZ78_008780	Uncharacterized protein. (247 aa)
	ASZ78_007384	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (184 aa)
	ASZ78_005043	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (203 aa)
	ASZ78_017111	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (708 aa)
	ASZ78_005072	Uncharacterized protein; Belongs to the cytochrome P450 family. (542 aa)
	ASZ78_008532	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (240 aa)
	ASZ78_015446	Uncharacterized protein. (1071 aa)
	ASZ78_015457	CTCK domain-containing protein. (188 aa)
	ASZ78_006659	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (224 aa)
	ASZ78_006660	Uncharacterized protein. (79 aa)
	ASZ78_002778	BZIP domain-containing protein. (582 aa)
	ASZ78_012471	Uncharacterized protein. (815 aa)
	ASZ78_004254	Uncharacterized protein. (601 aa)
	ASZ78_012987	Uncharacterized protein. (280 aa)
	ASZ78_012472	Ig_Tie2_1 domain-containing protein. (195 aa)
	ASZ78_011944	C3H1-type domain-containing protein. (681 aa)
	ASZ78_013905	Fibrinogen C-terminal domain-containing protein. (420 aa)
	ASZ78_013071	EGF-like domain-containing protein. (344 aa)
	ASZ78_003542	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (131 aa)
	ASZ78_005674	Uncharacterized protein. (1865 aa)
	ASZ78_015782	Uncharacterized protein. (264 aa)
	ASZ78_015795	Uncharacterized protein. (175 aa)
	ASZ78_010725	Uncharacterized protein. (1402 aa)
	ASZ78_005736	Uncharacterized protein. (167 aa)
	ASZ78_016771	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1345 aa)
	ASZ78_008666	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (425 aa)
	ASZ78_000419	Uncharacterized protein. (1041 aa)
	ASZ78_009624	ZP domain-containing protein. (643 aa)
	ASZ78_004908	Uncharacterized protein. (599 aa)

Your Current Organism:

Callipepla squamata

NCBI taxonomy Id: 9009
Other names: C. squamata, scaled quail

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASZ78_000419	ASZ78_000732	A0A226NM03	A0A226M8B6	Uncharacterized protein.	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family.	0.523
ASZ78_000419	ASZ78_001340	A0A226NM03	A0A226MKX2	Uncharacterized protein.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.793
ASZ78_000419	ASZ78_003542	A0A226NM03	A0A226NHE6	Uncharacterized protein.	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	0.787
ASZ78_000419	ASZ78_005043	A0A226NM03	A0A226NCU5	Uncharacterized protein.	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	0.804
ASZ78_000419	ASZ78_006659	A0A226NM03	A0A226NEL9	Uncharacterized protein.	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	0.710
ASZ78_000419	ASZ78_006660	A0A226NM03	A0A226NEM4	Uncharacterized protein.	Uncharacterized protein.	0.710
ASZ78_000419	ASZ78_006773	A0A226NM03	A0A226MVG4	Uncharacterized protein.	Uncharacterized protein.	0.424
ASZ78_000419	ASZ78_006875	A0A226NM03	A0A226N6J3	Uncharacterized protein.	PH domain-containing protein.	0.472
ASZ78_000419	ASZ78_006877	A0A226NM03	A0A226N638	Uncharacterized protein.	Uncharacterized protein.	0.472
ASZ78_000419	ASZ78_007384	A0A226NM03	A0A226NBT3	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.786
ASZ78_000419	ASZ78_008196	A0A226NM03	A0A226MDE6	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.523
ASZ78_000419	ASZ78_008532	A0A226NM03	A0A226ND58	Uncharacterized protein.	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	0.779
ASZ78_000419	ASZ78_012471	A0A226NM03	A0A226NFA1	Uncharacterized protein.	Uncharacterized protein.	0.531
ASZ78_000419	ASZ78_012472	A0A226NM03	A0A226NFQ9	Uncharacterized protein.	Ig_Tie2_1 domain-containing protein.	0.600
ASZ78_000419	ASZ78_013758	A0A226NM03	A0A226MMR5	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.806
ASZ78_000419	ASZ78_013905	A0A226NM03	A0A226NGB6	Uncharacterized protein.	Fibrinogen C-terminal domain-containing protein.	0.569
ASZ78_000419	ASZ78_014677	A0A226NM03	A0A226MNE7	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.523
ASZ78_000419	ASZ78_015782	A0A226NM03	A0A226NHY5	Uncharacterized protein.	Uncharacterized protein.	0.479
ASZ78_000419	ASZ78_015795	A0A226NM03	A0A226NI05	Uncharacterized protein.	Uncharacterized protein.	0.478
ASZ78_000732	ASZ78_000419	A0A226M8B6	A0A226NM03	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.523