(128 nodes) Stem cell differentiation network (Callipepla squamata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ASZ78_007166	Uncharacterized protein; Belongs to the semaphorin family. (328 aa)
	ASZ78_011418	Homeobox domain-containing protein. (240 aa)
	ASZ78_013143	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (683 aa)
	ASZ78_015617	Uncharacterized protein. (415 aa)
	ASZ78_016949	Uncharacterized protein; Belongs to the semaphorin family. (739 aa)
	ASZ78_001756	Uncharacterized protein; Belongs to the semaphorin family. (602 aa)
	ASZ78_003842	TGF_BETA_2 domain-containing protein. (168 aa)
	ASZ78_013756	Uncharacterized protein. (569 aa)
	ASZ78_001757	Sema domain-containing protein. (106 aa)
	ASZ78_003929	PCI domain-containing protein. (400 aa)
	ASZ78_014307	TBX domain-containing protein. (732 aa)
	ASZ78_000606	Uncharacterized protein. (102 aa)
	ASZ78_004822	Uncharacterized protein. (416 aa)
	ASZ78_004823	Sema domain-containing protein; Belongs to the semaphorin family. (744 aa)
	ASZ78_000836	Uncharacterized protein. (163 aa)
	ASZ78_008243	HMG box domain-containing protein. (496 aa)
	ASZ78_000858	PWWP domain-containing protein. (786 aa)
	ASZ78_006927	Uncharacterized protein; Belongs to the semaphorin family. (789 aa)
	ASZ78_006938	Uncharacterized protein; Belongs to the semaphorin family. (659 aa)
	ASZ78_005443	Fork-head domain-containing protein. (478 aa)
	ASZ78_006932	Uncharacterized protein; Belongs to the semaphorin family. (796 aa)
	ASZ78_005984	Noggin; Belongs to the noggin family. (223 aa)
	ASZ78_016865	G_PROTEIN_RECEP_F1_2 domain-containing protein. (232 aa)
	ASZ78_016866	G_PROTEIN_RECEP_F1_2 domain-containing protein. (230 aa)
	ASZ78_009260	Uncharacterized protein. (602 aa)
	ASZ78_002473	Uncharacterized protein. (893 aa)
	ASZ78_004810	Annexin. (705 aa)
	ASZ78_004801	LisH domain-containing protein. (1026 aa)
	ASZ78_010105	Uncharacterized protein. (95 aa)
	ASZ78_004222	Uncharacterized protein. (329 aa)
	ASZ78_001874	LisH domain-containing protein. (609 aa)
	ASZ78_013803	Ig-like domain-containing protein. (575 aa)
	ASZ78_012312	Uncharacterized protein. (205 aa)
	ASZ78_003584	Uncharacterized protein. (288 aa)
	ASZ78_011084	Phosphatase and actin regulator. (544 aa)
	ASZ78_011069	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (863 aa)
	ASZ78_006142	Fork-head domain-containing protein. (367 aa)
	ASZ78_001155	MTS domain-containing protein. (167 aa)
	ASZ78_006094	Uncharacterized protein. (166 aa)
	ASZ78_009725	TGF_BETA_2 domain-containing protein. (192 aa)
	ASZ78_014419	HMG box domain-containing protein. (497 aa)
	ASZ78_006143	Uncharacterized protein. (180 aa)
	ASZ78_001336	Uncharacterized protein. (496 aa)
	ASZ78_014937	Sema domain-containing protein. (522 aa)
	ASZ78_006311	Sema domain-containing protein; Belongs to the semaphorin family. (944 aa)
	ASZ78_000710	Homeobox domain-containing protein. (302 aa)
	ASZ78_004587	PUM-HD domain-containing protein. (944 aa)
	ASZ78_000725	Uncharacterized protein. (2519 aa)
	ASZ78_010487	G_PROTEIN_RECEP_F1_2 domain-containing protein. (462 aa)
	ASZ78_009373	Sema domain-containing protein; Belongs to the semaphorin family. (781 aa)
	ASZ78_008025	Uncharacterized protein; Belongs to the semaphorin family. (868 aa)
	ASZ78_011259	Thyroglobulin type-1 domain-containing protein. (282 aa)
	ASZ78_003359	Uncharacterized protein. (362 aa)
	ASZ78_003360	Sema domain-containing protein. (61 aa)
	ASZ78_006399	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (796 aa)
	ASZ78_003361	Uncharacterized protein; Belongs to the semaphorin family. (568 aa)
	ASZ78_003362	Sema domain-containing protein; Belongs to the semaphorin family. (631 aa)
	ASZ78_002576	Uncharacterized protein; Belongs to the semaphorin family. (716 aa)
	ASZ78_011193	Sema domain-containing protein; Belongs to the semaphorin family. (1020 aa)
	ASZ78_014210	Homeobox domain-containing protein. (237 aa)
	ASZ78_002535	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (355 aa)
	ASZ78_016203	Uncharacterized protein. (2373 aa)
	ASZ78_002083	Uncharacterized protein. (481 aa)
	ASZ78_005959	Neuropilin; Belongs to the neuropilin family. (846 aa)
	ASZ78_014985	Uncharacterized protein. (404 aa)
	ASZ78_009745	HNF-1_N domain-containing protein. (268 aa)
	ASZ78_007379	Uncharacterized protein. (393 aa)
	ASZ78_009768	TBX domain-containing protein. (594 aa)
	ASZ78_013834	Uncharacterized protein. (104 aa)
	ASZ78_008349	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (666 aa)
	ASZ78_007380	Uncharacterized protein. (565 aa)
	ASZ78_009770	Uncharacterized protein. (71 aa)
	ASZ78_006233	Cadherin_C domain-containing protein; Cadherins are calcium-dependent cell adhesion proteins. (123 aa)
	ASZ78_006232	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (701 aa)
	ASZ78_016986	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (463 aa)
	ASZ78_014134	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1083 aa)
	ASZ78_016630	Uncharacterized protein. (1030 aa)
	ASZ78_015041	Sema domain-containing protein. (186 aa)
	ASZ78_015042	Uncharacterized protein. (487 aa)
	ASZ78_016631	Uncharacterized protein. (276 aa)
	ASZ78_015457	CTCK domain-containing protein. (188 aa)
	ASZ78_014609	Sema domain-containing protein; Belongs to the semaphorin family. (608 aa)
	ASZ78_008588	Uncharacterized protein. (239 aa)
	ASZ78_012083	Uncharacterized protein. (145 aa)
	ASZ78_008318	Uncharacterized protein. (88 aa)
	ASZ78_012304	Sema domain-containing protein. (107 aa)
	ASZ78_010864	Uncharacterized protein. (387 aa)
	ASZ78_001405	Uncharacterized protein. (200 aa)
	ASZ78_010654	Uncharacterized protein. (197 aa)
	ASZ78_003866	Uncharacterized protein. (276 aa)
	ASZ78_004920	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)
	ASZ78_013222	Sema domain-containing protein; Belongs to the semaphorin family. (457 aa)
	ASZ78_005215	Uncharacterized protein. (456 aa)
	ASZ78_004211	Mothers against decapentaplegic homolog. (479 aa)
	ASZ78_012607	Uncharacterized protein. (1360 aa)
	ASZ78_006188	Fork-head domain-containing protein. (462 aa)
	ASZ78_003350	Annexin. (657 aa)
	ASZ78_002714	Uncharacterized protein. (655 aa)
	ASZ78_009236	Homeobox domain-containing protein. (278 aa)
	ASZ78_007484	Uncharacterized protein. (1693 aa)
	ASZ78_006376	Uncharacterized protein. (380 aa)
	ASZ78_002298	TGF_BETA_2 domain-containing protein. (199 aa)
	ASZ78_016322	MADS-box domain-containing protein. (437 aa)
	ASZ78_014553	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (542 aa)
	ASZ78_011294	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (726 aa)
	ASZ78_002202	HMG box domain-containing protein. (470 aa)
	ASZ78_012930	Uncharacterized protein. (133 aa)
	ASZ78_016680	Uncharacterized protein. (924 aa)
	ASZ78_014580	BTB domain-containing protein. (575 aa)
	ASZ78_008658	T-box_assoc domain-containing protein. (593 aa)
	ASZ78_016662	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (376 aa)
	ASZ78_012270	Homeobox protein. (333 aa)
	ASZ78_016372	Uncharacterized protein. (633 aa)
	ASZ78_003295	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1068 aa)
	ASZ78_016373	JmjN domain-containing protein. (646 aa)
	ASZ78_005536	Uncharacterized protein. (418 aa)
	ASZ78_014691	Homeobox domain-containing protein. (265 aa)
	ASZ78_006003	BH4_2 domain-containing protein. (226 aa)
	ASZ78_010875	Sema domain-containing protein; Belongs to the semaphorin family. (786 aa)
	ASZ78_015913	BTB domain-containing protein. (578 aa)
	ASZ78_010961	Uncharacterized protein; Belongs to the cytochrome P450 family. (585 aa)
	ASZ78_013539	Homeobox domain-containing protein. (149 aa)
	ASZ78_003546	BZIP domain-containing protein. (126 aa)
	ASZ78_011594	Uncharacterized protein. (545 aa)
	ASZ78_011901	EF-hand domain-containing protein. (114 aa)
	ASZ78_006665	Uncharacterized protein. (265 aa)
	ASZ78_004821	SAP domain-containing protein. (844 aa)
	ASZ78_007163	Sema domain-containing protein. (224 aa)

Your Current Organism:

Callipepla squamata

NCBI taxonomy Id: 9009
Other names: C. squamata, scaled quail

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASZ78_000710	ASZ78_004920	A0A226N257	A0A226MDU5	Homeobox domain-containing protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.529
ASZ78_000725	ASZ78_002714	A0A226N317	A0A226NEJ1	Uncharacterized protein.	Uncharacterized protein.	0.462
ASZ78_000725	ASZ78_004920	A0A226N317	A0A226MDU5	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.417
ASZ78_000836	ASZ78_015913	A0A226MPV3	A0A226NIM6	Uncharacterized protein.	BTB domain-containing protein.	0.571
ASZ78_000858	ASZ78_006399	A0A226MRS0	A0A226N634	PWWP domain-containing protein.	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.	0.876
ASZ78_000858	ASZ78_010961	A0A226MRS0	A0A226NI78	PWWP domain-containing protein.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.400
ASZ78_000858	ASZ78_011294	A0A226MRS0	A0A226NP07	PWWP domain-containing protein.	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.	0.896
ASZ78_001336	ASZ78_002714	A0A226N0Q7	A0A226NEJ1	Uncharacterized protein.	Uncharacterized protein.	0.874
ASZ78_001336	ASZ78_006094	A0A226N0Q7	A0A226MZN6	Uncharacterized protein.	Uncharacterized protein.	0.555
ASZ78_001336	ASZ78_006232	A0A226N0Q7	A0A226NCL9	Uncharacterized protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.595
ASZ78_001336	ASZ78_006233	A0A226N0Q7	A0A226NCJ7	Uncharacterized protein.	Cadherin_C domain-containing protein; Cadherins are calcium-dependent cell adhesion proteins.	0.595
ASZ78_001336	ASZ78_007379	A0A226N0Q7	A0A226NBH9	Uncharacterized protein.	Uncharacterized protein.	0.923
ASZ78_001336	ASZ78_008349	A0A226N0Q7	A0A226NBR7	Uncharacterized protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.595
ASZ78_001405	ASZ78_002298	A0A226MBP4	A0A226MIE7	Uncharacterized protein.	TGF_BETA_2 domain-containing protein.	0.479
ASZ78_001405	ASZ78_006376	A0A226MBP4	A0A226MIC3	Uncharacterized protein.	Uncharacterized protein.	0.899
ASZ78_001405	ASZ78_010105	A0A226MBP4	A0A226MWE4	Uncharacterized protein.	Uncharacterized protein.	0.899
ASZ78_001756	ASZ78_001757	A0A226MM78	A0A226MMT6	Uncharacterized protein; Belongs to the semaphorin family.	Sema domain-containing protein.	0.429
ASZ78_001756	ASZ78_003361	A0A226MM78	A0A226N666	Uncharacterized protein; Belongs to the semaphorin family.	Uncharacterized protein; Belongs to the semaphorin family.	0.427
ASZ78_001756	ASZ78_004822	A0A226MM78	A0A226MPL1	Uncharacterized protein; Belongs to the semaphorin family.	Uncharacterized protein.	0.416
ASZ78_001756	ASZ78_006094	A0A226MM78	A0A226MZN6	Uncharacterized protein; Belongs to the semaphorin family.	Uncharacterized protein.	0.400