(76 nodes) Digestive system development network (Callipepla squamata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ASZ78_014096	Uncharacterized protein. (376 aa)
	ASZ78_013089	Nipped-B protein. (2121 aa)
	ASZ78_003552	Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
	ASZ78_010929	Uncharacterized protein. (284 aa)
	ASZ78_016715	Uncharacterized protein. (366 aa)
	ASZ78_006003	BH4_2 domain-containing protein. (226 aa)
	ASZ78_006599	Uncharacterized protein. (822 aa)
	ASZ78_005606	WD_REPEATS_REGION domain-containing protein. (1284 aa)
	ASZ78_015246	Homeobox domain-containing protein. (370 aa)
	ASZ78_010036	BHLH domain-containing protein. (196 aa)
	ASZ78_012270	Homeobox protein. (333 aa)
	ASZ78_010044	WD_REPEATS_REGION domain-containing protein. (949 aa)
	ASZ78_010045	SH3 domain-containing protein. (110 aa)
	SRP54	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (384 aa)
	ASZ78_001339	Uncharacterized protein. (292 aa)
	ASZ78_006531	Uncharacterized protein. (224 aa)
	ASZ78_015499	Uncharacterized protein. (96 aa)
	ASZ78_015498	Uncharacterized protein. (84 aa)
	ASZ78_015496	Uncharacterized protein. (217 aa)
	ASZ78_015497	Uncharacterized protein. (106 aa)
	CXCL8	Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (95 aa)
	ASZ78_006729	Uncharacterized protein. (247 aa)
	ASZ78_009235	Homeobox domain-containing protein. (231 aa)
	ASZ78_009236	Homeobox domain-containing protein. (278 aa)
	ASZ78_012441	DUF3452 domain-containing protein. (326 aa)
	ASZ78_012442	RB_A domain-containing protein. (205 aa)
	ASZ78_002298	TGF_BETA_2 domain-containing protein. (199 aa)
	ASZ78_004821	SAP domain-containing protein. (844 aa)
	ASZ78_005141	Uncharacterized protein. (1610 aa)
	ASZ78_000734	Uncharacterized protein. (797 aa)
	ASZ78_005379	BHLH domain-containing protein. (218 aa)
	ASZ78_013143	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (683 aa)
	ASZ78_003947	Uncharacterized protein. (256 aa)
	ASZ78_008521	RRM domain-containing protein. (197 aa)
	ASZ78_014376	TGF_BETA_2 domain-containing protein. (404 aa)
	ASZ78_011823	G_PROTEIN_RECEP_F1_2 domain-containing protein. (926 aa)
	ASZ78_008243	HMG box domain-containing protein. (496 aa)
	ASZ78_005444	Fork-head domain-containing protein. (303 aa)
	ASZ78_005446	Fork-head domain-containing protein. (406 aa)
	ASZ78_009485	Dynein assembly factor 1, axonemal. (377 aa)
	ASZ78_016865	G_PROTEIN_RECEP_F1_2 domain-containing protein. (232 aa)
	ASZ78_016850	C2H2-type domain-containing protein. (411 aa)
	ASZ78_016866	G_PROTEIN_RECEP_F1_2 domain-containing protein. (230 aa)
	ASZ78_013803	Ig-like domain-containing protein. (575 aa)
	ASZ78_006140	Fork-head domain-containing protein. (387 aa)
	ASZ78_017013	Uncharacterized protein. (829 aa)
	ASZ78_017012	Cobl domain-containing protein. (225 aa)
	ASZ78_001086	Homeobox domain-containing protein. (270 aa)
	ASZ78_013634	Uncharacterized protein. (936 aa)
	ASZ78_002628	Protein kinase domain-containing protein. (452 aa)
	ASZ78_007840	Homeobox domain-containing protein. (177 aa)
	ASZ78_013792	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (214 aa)
	ASZ78_011245	Uncharacterized protein. (459 aa)
	ASZ78_006477	Protein YIPF. (225 aa)
	ASZ78_003868	PIP49_C domain-containing protein. (497 aa)
	ASZ78_006399	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (796 aa)
	ASZ78_008832	Ion_trans domain-containing protein; Belongs to the potassium channel family. (305 aa)
	ASZ78_002535	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (355 aa)
	ASZ78_002044	I/LWEQ domain-containing protein. (966 aa)
	ASZ78_001682	Uncharacterized protein. (401 aa)
	ASZ78_003696	Uncharacterized protein. (162 aa)
	ASZ78_015961	Uncharacterized protein. (345 aa)
	ASZ78_008749	Uncharacterized protein. (303 aa)
	ASZ78_009745	HNF-1_N domain-containing protein. (268 aa)
	ASZ78_001588	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (106 aa)
	ASZ78_001587	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (82 aa)
	ASZ78_016615	Uncharacterized protein. (179 aa)
	ASZ78_001586	Uncharacterized protein. (177 aa)
	ASZ78_014615	Uncharacterized protein. (477 aa)
	ASZ78_004437	Uncharacterized protein. (377 aa)
	ASZ78_015059	FERM domain-containing protein. (751 aa)
	ASZ78_002714	Uncharacterized protein. (655 aa)
	ASZ78_011580	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (175 aa)
	ASZ78_013874	Uncharacterized protein. (493 aa)
	ASZ78_002230	Uncharacterized protein. (4309 aa)
	ASZ78_011327	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (408 aa)

Your Current Organism:

Callipepla squamata

NCBI taxonomy Id: 9009
Other names: C. squamata, scaled quail

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASZ78_001339	ASZ78_006531	A0A226MCB3	A0A226MCW7	Uncharacterized protein.	Uncharacterized protein.	0.899
ASZ78_001339	ASZ78_015496	A0A226MCB3	A0A226MDJ2	Uncharacterized protein.	Uncharacterized protein.	0.917
ASZ78_001339	ASZ78_015497	A0A226MCB3	A0A226MDY2	Uncharacterized protein.	Uncharacterized protein.	0.923
ASZ78_001339	ASZ78_015498	A0A226MCB3	A0A226MDD4	Uncharacterized protein.	Uncharacterized protein.	0.899
ASZ78_001586	ASZ78_001587	A0A226NDD5	A0A226ND89	Uncharacterized protein.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.916
ASZ78_001586	ASZ78_001588	A0A226NDD5	A0A226NCL1	Uncharacterized protein.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.961
ASZ78_001587	ASZ78_001586	A0A226ND89	A0A226NDD5	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Uncharacterized protein.	0.916
ASZ78_001587	ASZ78_001588	A0A226ND89	A0A226NCL1	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.611
ASZ78_001588	ASZ78_001586	A0A226NCL1	A0A226NDD5	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Uncharacterized protein.	0.961
ASZ78_001588	ASZ78_001587	A0A226NCL1	A0A226ND89	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.611
ASZ78_002298	ASZ78_003552	A0A226MIE7	A0A226NHF3	TGF_BETA_2 domain-containing protein.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.949
ASZ78_002298	ASZ78_008243	A0A226MIE7	A0A226MR05	TGF_BETA_2 domain-containing protein.	HMG box domain-containing protein.	0.529
ASZ78_002535	ASZ78_013803	A0A226N862	A0A226MXN6	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Ig-like domain-containing protein.	0.468
ASZ78_002535	ASZ78_016865	A0A226N862	A0A226MTP8	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.907
ASZ78_002628	ASZ78_006477	A0A226N313	A0A226N588	Protein kinase domain-containing protein.	Protein YIPF.	0.499
ASZ78_002714	ASZ78_006003	A0A226NEJ1	A0A226NIW8	Uncharacterized protein.	BH4_2 domain-containing protein.	0.467
ASZ78_002714	ASZ78_008243	A0A226NEJ1	A0A226MR05	Uncharacterized protein.	HMG box domain-containing protein.	0.705
ASZ78_002714	ASZ78_010044	A0A226NEJ1	A0A226NL62	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.434
ASZ78_002714	ASZ78_010045	A0A226NEJ1	A0A226NLQ9	Uncharacterized protein.	SH3 domain-containing protein.	0.434
ASZ78_002714	ASZ78_012270	A0A226NEJ1	A0A226NL42	Uncharacterized protein.	Homeobox protein.	0.470