(124 nodes) Bone development network (Callipepla squamata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ASZ78_013106	Pep_M12B_propep domain-containing protein. (189 aa)
	ASZ78_012615	Uncharacterized protein. (1089 aa)
	ASZ78_014902	Uncharacterized protein. (575 aa)
	ASZ78_013235	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (670 aa)
	ASZ78_008123	LRRCT domain-containing protein. (715 aa)
	ASZ78_013803	Ig-like domain-containing protein. (575 aa)
	ASZ78_011076	WH2 domain-containing protein. (366 aa)
	ASZ78_001079	Uncharacterized protein. (42 aa)
	ASZ78_001090	DUF3528 domain-containing protein. (236 aa)
	ASZ78_000763	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (605 aa)
	ASZ78_001148	Uncharacterized protein. (242 aa)
	ASZ78_001161	Uncharacterized protein. (391 aa)
	ASZ78_006074	Alkaline phosphatase. (525 aa)
	ASZ78_006095	Fe2OG dioxygenase domain-containing protein. (738 aa)
	ASZ78_015019	Uncharacterized protein. (1069 aa)
	ASZ78_013676	Uncharacterized protein. (154 aa)
	ASZ78_013667	Uncharacterized protein. (323 aa)
	ASZ78_008473	Glyco_transf_64 domain-containing protein. (173 aa)
	ASZ78_005799	Mitogen-activated protein kinase. (351 aa)
	ASZ78_016145	Uncharacterized protein. (433 aa)
	ASZ78_013340	Uncharacterized protein. (452 aa)
	ASZ78_002929	Uncharacterized protein. (307 aa)
	ASZ78_017039	Uncharacterized protein. (217 aa)
	ASZ78_007242	Uncharacterized protein. (216 aa)
	ASZ78_006854	Uncharacterized protein. (310 aa)
	ASZ78_016693	Uncharacterized protein. (826 aa)
	ASZ78_004328	Uncharacterized protein. (267 aa)
	ASZ78_013437	Uncharacterized protein. (166 aa)
	ASZ78_011127	Uncharacterized protein. (202 aa)
	ASZ78_012083	Uncharacterized protein. (145 aa)
	ASZ78_015333	Uncharacterized protein. (239 aa)
	ASZ78_014797	Uncharacterized protein. (311 aa)
	ASZ78_009461	BTB domain-containing protein. (389 aa)
	ASZ78_009464	Uncharacterized protein. (189 aa)
	ASZ78_009373	Sema domain-containing protein; Belongs to the semaphorin family. (781 aa)
	ASZ78_006493	SH2 domain-containing protein. (1113 aa)
	ASZ78_013784	Uncharacterized protein. (352 aa)
	ASZ78_013793	Uncharacterized protein. (142 aa)
	ASZ78_008051	Uncharacterized protein. (1759 aa)
	ASZ78_006389	Uncharacterized protein. (144 aa)
	ASZ78_003116	Uncharacterized protein; Belongs to the cytochrome P450 family. (443 aa)
	ASZ78_008028	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (613 aa)
	ASZ78_000353	WD_REPEATS_REGION domain-containing protein. (638 aa)
	ASZ78_016255	BRCT domain-containing protein. (374 aa)
	ASZ78_006965	Uncharacterized protein. (247 aa)
	ASZ78_006066	Peptidase_M50 domain-containing protein. (381 aa)
	ASZ78_008989	NR LBD domain-containing protein. (265 aa)
	ASZ78_004841	TGF_BETA_2 domain-containing protein. (235 aa)
	ASZ78_008962	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1660 aa)
	ASZ78_002895	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (425 aa)
	ASZ78_002083	Uncharacterized protein. (481 aa)
	ASZ78_005935	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1071 aa)
	ASZ78_009949	Uncharacterized protein. (287 aa)
	ASZ78_016295	Uncharacterized protein. (453 aa)
	ASZ78_008328	Uncharacterized protein. (1098 aa)
	ASZ78_007384	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (184 aa)
	ASZ78_008351	60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family. (211 aa)
	ASZ78_012476	Uncharacterized protein. (863 aa)
	ASZ78_011598	Uncharacterized protein. (866 aa)
	ASZ78_012998	Uncharacterized protein. (232 aa)
	ASZ78_009699	Uncharacterized protein. (361 aa)
	ASZ78_005710	Uncharacterized protein. (182 aa)
	ASZ78_013890	Uncharacterized protein. (1061 aa)
	ASZ78_005709	Uncharacterized protein. (186 aa)
	ASZ78_013093	Uncharacterized protein. (178 aa)
	ASZ78_010246	TPR_REGION domain-containing protein. (222 aa)
	ASZ78_013539	Homeobox domain-containing protein. (149 aa)
	ASZ78_013110	Uncharacterized protein. (1215 aa)
	ASZ78_010889	Uncharacterized protein; Belongs to the heparin-binding growth factors family. (190 aa)
	ASZ78_016713	Homeobox domain-containing protein. (286 aa)
	ASZ78_016773	Uncharacterized protein. (1141 aa)
	ASZ78_014732	Fork-head domain-containing protein. (283 aa)
	ASZ78_012270	Homeobox protein. (333 aa)
	ASZ78_008666	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (425 aa)
	ASZ78_014714	GRIP domain-containing protein. (2051 aa)
	ASZ78_012257	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
	ASZ78_012942	Uncharacterized protein. (976 aa)
	ASZ78_016680	Uncharacterized protein. (924 aa)
	ASZ78_013287	Uncharacterized protein. (740 aa)
	ASZ78_010051	WD_REPEATS_REGION domain-containing protein. (326 aa)
	ASZ78_005358	Uncharacterized protein. (1136 aa)
	ASZ78_011366	Integrin beta; Belongs to the integrin beta chain family. (611 aa)
	ASZ78_005359	Uncharacterized protein. (682 aa)
	ASZ78_003427	Uncharacterized protein. (1964 aa)
	ASZ78_009597	Uncharacterized protein. (565 aa)
	ASZ78_011327	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (408 aa)
	ASZ78_011339	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (828 aa)
	ASZ78_011811	Olfactomedin-like domain-containing protein. (493 aa)
	ASZ78_013288	PX domain-containing protein. (82 aa)
	ASZ78_016438	ZnMc domain-containing protein. (486 aa)
	ASZ78_008243	HMG box domain-containing protein. (496 aa)
	ASZ78_000072	SH3 domain-containing protein. (292 aa)
	ASZ78_001757	Sema domain-containing protein. (106 aa)
	ASZ78_001130	DAN domain-containing protein. (269 aa)
	ASZ78_001131	Uncharacterized protein. (85 aa)
	ASZ78_001756	Uncharacterized protein; Belongs to the semaphorin family. (602 aa)
	ASZ78_001129	Calx-beta domain-containing protein. (249 aa)
	ASZ78_001128	Uncharacterized protein. (1772 aa)
	ASZ78_011428	Uncharacterized protein. (845 aa)
	ASZ78_015638	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (390 aa)
	ASZ78_005141	Uncharacterized protein. (1610 aa)
	ASZ78_002835	Homeobox domain-containing protein. (300 aa)
	ASZ78_016695	Uncharacterized protein. (371 aa)
	ASZ78_016322	MADS-box domain-containing protein. (437 aa)
	ASZ78_009333	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (318 aa)
	ASZ78_013488	Aa_trans domain-containing protein. (1115 aa)
	ASZ78_004357	Uncharacterized protein. (2454 aa)
	ASZ78_007210	MADS-box domain-containing protein. (562 aa)
	ASZ78_003350	Annexin. (657 aa)
	ASZ78_002912	Uncharacterized protein. (1144 aa)
	ASZ78_012041	Mitogen-activated protein kinase. (359 aa)
	ASZ78_010329	IPPc domain-containing protein. (729 aa)
	ASZ78_004922	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (205 aa)
	ASZ78_009102	Uncharacterized protein. (423 aa)
	ASZ78_006947	Uncharacterized protein. (321 aa)
	ASZ78_009853	Uncharacterized protein. (433 aa)
	ASZ78_002924	Uncharacterized protein. (203 aa)
	ASZ78_005881	Annexin. (343 aa)
	ASZ78_015567	Mothers against decapentaplegic homolog. (438 aa)
	ASZ78_000526	Uncharacterized protein. (287 aa)
	ASZ78_004771	Uncharacterized protein. (1050 aa)
	ASZ78_004810	Annexin. (705 aa)
	ASZ78_012616	Uncharacterized protein. (217 aa)
	ASZ78_016522	Uncharacterized protein. (395 aa)

Your Current Organism:

Callipepla squamata

NCBI taxonomy Id: 9009
Other names: C. squamata, scaled quail

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASZ78_000072	ASZ78_011076	A0A226MNY1	A0A226MY37	SH3 domain-containing protein.	WH2 domain-containing protein.	0.965
ASZ78_000072	ASZ78_012998	A0A226MNY1	A0A226NG11	SH3 domain-containing protein.	Uncharacterized protein.	0.601
ASZ78_000353	ASZ78_005141	A0A226N6F4	A0A226MJZ1	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.997
ASZ78_000353	ASZ78_008351	A0A226N6F4	A0A226NC55	WD_REPEATS_REGION domain-containing protein.	60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family.	0.442
ASZ78_000353	ASZ78_008962	A0A226N6F4	A0A226N7Z3	WD_REPEATS_REGION domain-containing protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.463
ASZ78_000353	ASZ78_013235	A0A226N6F4	A0A226MX92	WD_REPEATS_REGION domain-containing protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.463
ASZ78_000526	ASZ78_006066	A0A226MU36	A0A226N7N9	Uncharacterized protein.	Peptidase_M50 domain-containing protein.	0.737
ASZ78_000526	ASZ78_006095	A0A226MU36	A0A226MZQ0	Uncharacterized protein.	Fe2OG dioxygenase domain-containing protein.	0.704
ASZ78_000763	ASZ78_004922	A0A226MYZ6	A0A226MDS5	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.496
ASZ78_000763	ASZ78_005799	A0A226MYZ6	A0A226N2T1	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Mitogen-activated protein kinase.	0.658
ASZ78_000763	ASZ78_006493	A0A226MYZ6	A0A226N532	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	SH2 domain-containing protein.	0.760
ASZ78_000763	ASZ78_007384	A0A226MYZ6	A0A226NBT3	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.518
ASZ78_000763	ASZ78_010329	A0A226MYZ6	A0A226MEA8	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	IPPc domain-containing protein.	0.751
ASZ78_000763	ASZ78_010889	A0A226MYZ6	A0A226NIE4	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Uncharacterized protein; Belongs to the heparin-binding growth factors family.	0.476
ASZ78_000763	ASZ78_011366	A0A226MYZ6	A0A226NN38	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Integrin beta; Belongs to the integrin beta chain family.	0.579
ASZ78_000763	ASZ78_012041	A0A226MYZ6	A0A226MFG6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Mitogen-activated protein kinase.	0.658
ASZ78_000763	ASZ78_012998	A0A226MYZ6	A0A226NG11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Uncharacterized protein.	0.619
ASZ78_000763	ASZ78_013793	A0A226MYZ6	A0A226N5C2	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Uncharacterized protein.	0.751
ASZ78_000763	ASZ78_013803	A0A226MYZ6	A0A226MXN6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Ig-like domain-containing protein.	0.794
ASZ78_000763	ASZ78_013890	A0A226MYZ6	A0A226NGJ0	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Uncharacterized protein.	0.540