(78 nodes) Kidney epithelium development network (Callipepla squamata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ASZ78_013792	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (214 aa)
	ASZ78_006507	MH1 domain-containing protein. (192 aa)
	ASZ78_008673	MH2 domain-containing protein. (207 aa)
	ASZ78_014791	PHB domain-containing protein. (382 aa)
	ASZ78_002334	Uncharacterized protein. (157 aa)
	ASZ78_004211	Mothers against decapentaplegic homolog. (479 aa)
	ASZ78_009133	Uncharacterized protein. (196 aa)
	ASZ78_009132	Uncharacterized protein. (507 aa)
	ASZ78_012609	Uncharacterized protein. (638 aa)
	ASZ78_013843	Uncharacterized protein. (452 aa)
	ASZ78_002835	Homeobox domain-containing protein. (300 aa)
	ASZ78_001340	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
	ASZ78_013143	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (683 aa)
	ASZ78_001771	Uncharacterized protein. (343 aa)
	ASZ78_001766	Uncharacterized protein. (400 aa)
	ASZ78_001130	DAN domain-containing protein. (269 aa)
	ASZ78_013758	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (113 aa)
	ASZ78_003952	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (119 aa)
	ASZ78_003951	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (219 aa)
	ASZ78_014311	Uncharacterized protein. (357 aa)
	ASZ78_014674	ICAT domain-containing protein. (83 aa)
	ASZ78_014376	TGF_BETA_2 domain-containing protein. (404 aa)
	ASZ78_011823	G_PROTEIN_RECEP_F1_2 domain-containing protein. (926 aa)
	ASZ78_008290	Uncharacterized protein. (1064 aa)
	ASZ78_008243	HMG box domain-containing protein. (496 aa)
	ASZ78_005443	Fork-head domain-containing protein. (478 aa)
	ASZ78_015567	Mothers against decapentaplegic homolog. (438 aa)
	ASZ78_007779	Uncharacterized protein. (1877 aa)
	ASZ78_009882	Uncharacterized protein. (830 aa)
	ASZ78_005984	Noggin; Belongs to the noggin family. (223 aa)
	ASZ78_016865	G_PROTEIN_RECEP_F1_2 domain-containing protein. (232 aa)
	ASZ78_016866	G_PROTEIN_RECEP_F1_2 domain-containing protein. (230 aa)
	ASZ78_011479	COMM domain-containing protein. (243 aa)
	ASZ78_002644	Mothers against decapentaplegic homolog. (363 aa)
	ASZ78_012114	Ephrin RBD domain-containing protein; Belongs to the ephrin family. (333 aa)
	ASZ78_001090	DUF3528 domain-containing protein. (236 aa)
	ASZ78_007435	Uncharacterized protein. (3158 aa)
	ASZ78_006142	Fork-head domain-containing protein. (367 aa)
	ASZ78_009725	TGF_BETA_2 domain-containing protein. (192 aa)
	ASZ78_006143	Uncharacterized protein. (180 aa)
	ASZ78_001359	Uncharacterized protein. (382 aa)
	ASZ78_013777	Uncharacterized protein. (284 aa)
	ASZ78_013254	Uncharacterized protein. (740 aa)
	ASZ78_011259	Thyroglobulin type-1 domain-containing protein. (282 aa)
	ASZ78_016797	Uncharacterized protein. (1753 aa)
	ASZ78_013732	Uncharacterized protein. (241 aa)
	ASZ78_002535	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (355 aa)
	ASZ78_009027	Homeobox domain-containing protein. (374 aa)
	ASZ78_003559	Uncharacterized protein. (296 aa)
	ASZ78_003652	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (143 aa)
	ASZ78_004975	Uncharacterized protein. (546 aa)
	ASZ78_016008	Thyroglobulin type-1 domain-containing protein. (303 aa)
	ASZ78_002984	Homeobox domain-containing protein. (453 aa)
	ASZ78_009754	Uncharacterized protein. (352 aa)
	ASZ78_009745	HNF-1_N domain-containing protein. (268 aa)
	ASZ78_006588	Ig-like domain-containing protein. (327 aa)
	ASZ78_017111	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (708 aa)
	ASZ78_014134	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1083 aa)
	ASZ78_015457	CTCK domain-containing protein. (188 aa)
	ASZ78_002714	Uncharacterized protein. (655 aa)
	ASZ78_006643	Uncharacterized protein. (981 aa)
	ASZ78_012993	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (197 aa)
	ASZ78_000663	Uncharacterized protein. (1788 aa)
	ASZ78_015117	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1522 aa)
	ASZ78_015118	Uncharacterized protein. (309 aa)
	ASZ78_010874	Uncharacterized protein. (643 aa)
	ASZ78_005631	Uncharacterized protein. (317 aa)
	ASZ78_010889	Uncharacterized protein; Belongs to the heparin-binding growth factors family. (190 aa)
	ASZ78_006003	BH4_2 domain-containing protein. (226 aa)
	ASZ78_003295	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1068 aa)
	ASZ78_010036	BHLH domain-containing protein. (196 aa)
	ASZ78_016662	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (376 aa)
	ASZ78_010044	WD_REPEATS_REGION domain-containing protein. (949 aa)
	ASZ78_010045	SH3 domain-containing protein. (110 aa)
	ASZ78_002230	Uncharacterized protein. (4309 aa)
	ASZ78_002202	HMG box domain-containing protein. (470 aa)
	ASZ78_003461	Mothers against decapentaplegic homolog. (408 aa)
	ASZ78_011320	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)

Your Current Organism:

Callipepla squamata

NCBI taxonomy Id: 9009
Other names: C. squamata, scaled quail

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASZ78_001130	ASZ78_003951	A0A226MMR2	A0A226MND9	DAN domain-containing protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.909
ASZ78_001130	ASZ78_003952	A0A226MMR2	A0A226MN36	DAN domain-containing protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.909
ASZ78_001130	ASZ78_013792	A0A226MMR2	A0A226N4M2	DAN domain-containing protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.920
ASZ78_001130	ASZ78_014376	A0A226MMR2	A0A226MNG7	DAN domain-containing protein.	TGF_BETA_2 domain-containing protein.	0.592
ASZ78_001340	ASZ78_003295	A0A226MKX2	A0A226NKL3	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.	0.755
ASZ78_001340	ASZ78_010889	A0A226MKX2	A0A226NIE4	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	Uncharacterized protein; Belongs to the heparin-binding growth factors family.	0.570
ASZ78_001340	ASZ78_012993	A0A226MKX2	A0A226NF45	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.518
ASZ78_001359	ASZ78_002202	A0A226N235	A0A226NN65	Uncharacterized protein.	HMG box domain-containing protein.	0.574
ASZ78_001359	ASZ78_003559	A0A226N235	A0A226N8X8	Uncharacterized protein.	Uncharacterized protein.	0.404
ASZ78_001359	ASZ78_004211	A0A226N235	A0A226MF11	Uncharacterized protein.	Mothers against decapentaplegic homolog.	0.406
ASZ78_001359	ASZ78_008243	A0A226N235	A0A226MR05	Uncharacterized protein.	HMG box domain-containing protein.	0.717
ASZ78_001359	ASZ78_009754	A0A226N235	A0A226NB76	Uncharacterized protein.	Uncharacterized protein.	0.604
ASZ78_001359	ASZ78_010036	A0A226N235	A0A226NL40	Uncharacterized protein.	BHLH domain-containing protein.	0.767
ASZ78_001359	ASZ78_010889	A0A226N235	A0A226NIE4	Uncharacterized protein.	Uncharacterized protein; Belongs to the heparin-binding growth factors family.	0.436
ASZ78_001359	ASZ78_013758	A0A226N235	A0A226MMR5	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.500
ASZ78_001359	ASZ78_014376	A0A226N235	A0A226MNG7	Uncharacterized protein.	TGF_BETA_2 domain-containing protein.	0.561
ASZ78_001359	ASZ78_014791	A0A226N235	A0A226MDD8	Uncharacterized protein.	PHB domain-containing protein.	0.598
ASZ78_002202	ASZ78_001359	A0A226NN65	A0A226N235	HMG box domain-containing protein.	Uncharacterized protein.	0.574
ASZ78_002202	ASZ78_002714	A0A226NN65	A0A226NEJ1	HMG box domain-containing protein.	Uncharacterized protein.	0.676
ASZ78_002230	ASZ78_006643	A0A226NM72	A0A226NES5	Uncharacterized protein.	Uncharacterized protein.	0.996