(32 nodes) Stem cell proliferation network (Callipepla squamata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ASZ78_014307	TBX domain-containing protein. (732 aa)
	ASZ78_011294	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (726 aa)
	ASZ78_005358	Uncharacterized protein. (1136 aa)
	ASZ78_010889	Uncharacterized protein; Belongs to the heparin-binding growth factors family. (190 aa)
	ASZ78_000652	RBR-type E3 ubiquitin transferase. (490 aa)
	ASZ78_016633	Uncharacterized protein. (391 aa)
	ASZ78_009770	Uncharacterized protein. (71 aa)
	ASZ78_009768	TBX domain-containing protein. (594 aa)
	ASZ78_008782	RING-type domain-containing protein. (802 aa)
	ASZ78_006399	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (796 aa)
	ASZ78_014020	DUF3668 domain-containing protein. (757 aa)
	ASZ78_004922	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (205 aa)
	ASZ78_007211	IF rod domain-containing protein; Belongs to the intermediate filament family. (1698 aa)
	ASZ78_003976	YjeF N-terminal domain-containing protein. (247 aa)
	ASZ78_003963	Uncharacterized protein. (332 aa)
	ASZ78_001705	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1220 aa)
	ASZ78_013373	RING-type domain-containing protein. (829 aa)
	ASZ78_000285	Uncharacterized protein. (428 aa)
	ASZ78_013792	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (214 aa)
	ASZ78_012323	Uncharacterized protein. (1082 aa)
	ASZ78_015335	Uncharacterized protein. (932 aa)
	ASZ78_001082	Homeobox domain-containing protein. (413 aa)
	ASZ78_011068	Uncharacterized protein. (413 aa)
	ASZ78_016523	Uncharacterized protein. (132 aa)
	ASZ78_011455	ANK_REP_REGION domain-containing protein. (123 aa)
	ASZ78_011553	Uncharacterized protein. (514 aa)
	ASZ78_011556	B box-type domain-containing protein. (338 aa)
	ASZ78_008412	Uncharacterized protein. (108 aa)
	ASZ78_008411	Tower domain-containing protein. (2902 aa)
	ASZ78_011818	Uncharacterized protein. (245 aa)
	ASZ78_008243	HMG box domain-containing protein. (496 aa)
	ASZ78_013758	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (113 aa)

Your Current Organism:

Callipepla squamata

NCBI taxonomy Id: 9009
Other names: C. squamata, scaled quail

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASZ78_001705	ASZ78_004922	A0A226MHK7	A0A226MDS5	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.969
ASZ78_001705	ASZ78_010889	A0A226MHK7	A0A226NIE4	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Uncharacterized protein; Belongs to the heparin-binding growth factors family.	0.969
ASZ78_001705	ASZ78_013758	A0A226MHK7	A0A226MMR5	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.987
ASZ78_003963	ASZ78_011294	A0A226MGZ1	A0A226NP07	Uncharacterized protein.	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.	0.406
ASZ78_003963	ASZ78_014020	A0A226MGZ1	A0A226N593	Uncharacterized protein.	DUF3668 domain-containing protein.	0.440
ASZ78_004922	ASZ78_001705	A0A226MDS5	A0A226MHK7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.969
ASZ78_004922	ASZ78_008243	A0A226MDS5	A0A226MR05	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	HMG box domain-containing protein.	0.574
ASZ78_004922	ASZ78_010889	A0A226MDS5	A0A226NIE4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Uncharacterized protein; Belongs to the heparin-binding growth factors family.	0.676
ASZ78_004922	ASZ78_013758	A0A226MDS5	A0A226MMR5	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.479
ASZ78_006399	ASZ78_008411	A0A226N634	A0A226MS07	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.	Tower domain-containing protein.	0.571
ASZ78_006399	ASZ78_008412	A0A226N634	A0A226MS32	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.	Uncharacterized protein.	0.571
ASZ78_006399	ASZ78_011455	A0A226N634	A0A226MVG0	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.	ANK_REP_REGION domain-containing protein.	0.595
ASZ78_008243	ASZ78_004922	A0A226MR05	A0A226MDS5	HMG box domain-containing protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.574
ASZ78_008243	ASZ78_010889	A0A226MR05	A0A226NIE4	HMG box domain-containing protein.	Uncharacterized protein; Belongs to the heparin-binding growth factors family.	0.580
ASZ78_008243	ASZ78_011818	A0A226MR05	A0A226MRW5	HMG box domain-containing protein.	Uncharacterized protein.	0.460
ASZ78_008243	ASZ78_013758	A0A226MR05	A0A226MMR5	HMG box domain-containing protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.578
ASZ78_008411	ASZ78_006399	A0A226MS07	A0A226N634	Tower domain-containing protein.	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.	0.571
ASZ78_008411	ASZ78_008412	A0A226MS07	A0A226MS32	Tower domain-containing protein.	Uncharacterized protein.	0.911
ASZ78_008411	ASZ78_011294	A0A226MS07	A0A226NP07	Tower domain-containing protein.	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.	0.405
ASZ78_008412	ASZ78_006399	A0A226MS32	A0A226N634	Uncharacterized protein.	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.	0.571